3MK6

Substrate and Inhibitor Binding to Pank

Summary for 3MK6

Entry DOI	10.2210/pdb3mk6/pdb
Related	2I7P
Descriptor	Pantothenate kinase 3, ACETYL COENZYME *A, GLYCEROL, ... (4 entities in total)
Functional Keywords	pank, inhibitor, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : Q9H999
Total number of polymer chains	4
Total formula weight	170620.35
Authors	Yun, M.-K.,White, S.W. (deposition date: 2010-04-14, release date: 2010-09-15, Last modification date: 2023-09-06)
Primary citation	Leonardi, R.,Zhang, Y.M.,Yun, M.K.,Zhou, R.,Zeng, F.Y.,Lin, W.,Cui, J.,Chen, T.,Rock, C.O.,White, S.W.,Jackowski, S. Modulation of Pantothenate Kinase 3 Activity by Small Molecules that Interact with the Substrate/Allosteric Regulatory Domain. Chem.Biol., 17:892-902, 2010 Cited by PubMed: 20797618 DOI: 10.1016/j.chembiol.2010.06.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.98 Å)

Structure validation