2I7N
Crystal structure of human PANK1 alpha: the catalytic core domain in complex with AcCoA
Summary for 2I7N
Entry DOI | 10.2210/pdb2i7n/pdb |
Related | 2I7P |
Descriptor | Pantothenate kinase 1, ACETYL COENZYME *A (3 entities in total) |
Functional Keywords | pank, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q8TE04 |
Total number of polymer chains | 2 |
Total formula weight | 81971.52 |
Authors | Hong, B.S.,Wang, L.,Tempel, W.,Loppnau, P.,Allali-Hassani, A.,Arrowsmith, C.H.,Edwards, A.M.,Sundstrom, M.,Weigelt, J.,Bochkarev, A.,Park, H.W. (deposition date: 2006-08-31, release date: 2006-12-26, Last modification date: 2024-02-21) |
Primary citation | Hong, B.S.,Senisterra, G.,Rabeh, W.M.,Vedadi, M.,Leonardi, R.,Zhang, Y.M.,Rock, C.O.,Jackowski, S.,Park, H.W. Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder. J.Biol.Chem., 282:27984-27993, 2007 Cited by PubMed: 17631502DOI: 10.1074/jbc.M701915200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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