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6ELK
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C.ELEGANS MNSOD-3 MUTANT - Q142H
Descriptor:Superoxide dismutase [Mn] 2, mitochondrial, MANGANESE (II) ION, ...
Authors:Hunter, G.J., Trinh, C.H., Hunter, T.
Deposit date:2017-09-29
Release date:2017-12-06
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A Single Mutation is Sufficient to Modify the Metal Selectivity and Specificity of a Eukaryotic Manganese Superoxide Dismutase to Encompass Iron.
Chemistry, 24, 2018
3DC5
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CRYSTAL STRUCTURE OF A MANGANESE SUPEROXIDE DISMUTASES FROM CAENORHABDITIS ELEGANS
Descriptor:Superoxide dismutase [Mn] 2, MANGANESE (II) ION, MALONATE ION
Authors:Trinh, C.H., Hunter, T., Stewart, E.E., Phillips, S.E.V., Hunter, G.J.
Deposit date:2008-06-03
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Purification, crystallization and X-ray structures of the two manganese superoxide dismutases from Caenorhabditis elegans
Acta Crystallogr.,Sect.F, 64, 2008
3DC6
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CRYSTAL STRUCTURE OF A MANGANESE SUPEROXIDE DISMUTASES FROM CAENORHABDITIS ELEGANS
Descriptor:Superoxide dismutase [Mn] 1, MANGANESE (II) ION, SULFATE ION
Authors:Trinh, C.H., Hunter, T., Stewart, E.E., Phillips, S.E.V., Hunter, G.J.
Deposit date:2008-06-03
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Purification, crystallization and X-ray structures of the two manganese superoxide dismutases from Caenorhabditis elegans
Acta Crystallogr.,Sect.F, 64, 2008
4X9Q
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MNSOD-3 ROOM TEMPERATURE STRUCTURE
Descriptor:Superoxide dismutase [Mn] 2, mitochondrial, MANGANESE (II) ION, ...
Authors:Hunter, G.J., Trinh, C.H., Hunter, T., Bonetta, R., Stewart, E.E.
Deposit date:2014-12-11
Release date:2015-11-25
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:The structure of the Caenorhabditis elegans manganese superoxide dismutase MnSOD-3-azide complex.
Protein Sci., 24, 2015
5AG2
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SOD-3 AZIDE COMPLEX
Descriptor:SUPEROXIDE DISMUTASE [MN] 2, MITOCHONDRIAL, MANGANESE (II) ION, ...
Authors:Hunter, G.J., Trinh, C.H., Bonetta, R., Stewart, E.E., Cabelli, D.E., Hunter, T.
Deposit date:2015-01-27
Release date:2016-01-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:The Structure of the Caenorhabditis Elegans Manganese Superoxide Dismutase Mnsod-3-Azide Complex.
Protein Sci., 24, 2015
1PIN
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PIN1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM HOMO SAPIENS
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE, ALANINE, PROLINE, ...
Authors:Noel, J.P., Ranganathan, R., Hunter, T.
Deposit date:1998-06-21
Release date:1998-10-14
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent.
Cell(Cambridge,Mass.), 89, 1997
1F3H
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X-RAY CRYSTAL STRUCTURE OF THE HUMAN ANTI-APOPTOTIC PROTEIN SURVIVIN
Descriptor:SURVIVIN, ZINC ION, SULFATE ION
Authors:Verdecia, M.A., Huang, H., Dutil, E., Hunter, T., Noel, J.P.
Deposit date:2000-06-03
Release date:2000-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement.
Nat.Struct.Biol., 7, 2000
1F8A
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STRUCTURAL BASIS FOR THE PHOSPHOSERINE-PROLINE RECOGNITION BY GROUP IV WW DOMAINS
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1, Y(SEP)PT(SEP)S PEPTIDE
Authors:Verdecia, M.A., Bowman, M.E., Lu, K.P., Hunter, T., Noel, J.P.
Deposit date:2000-06-29
Release date:2000-08-23
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural basis for phosphoserine-proline recognition by group IV WW domains.
Nat.Struct.Biol., 7, 2000
1ND7
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CONFORMATIONAL FLEXIBILITY UNDERLIES UBIQUITIN LIGATION MEDIATED BY THE WWP1 HECT DOMAIN E3 LIGASE
Descriptor:WW domain-containing protein 1
Authors:Verdecia, M.A., Joaziero, C.A.P., Wells, N.J., Ferrer, J.-L., Bowman, M.E., Hunter, T., Noel, J.P.
Deposit date:2002-12-08
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational Flexibility Underlies Ubiquitin Ligation Mediated by the WWP1 HECT domain E3 Ligase
Mol.Cell, 11, 2003
1P13
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CRYSTAL STRUCTURE OF THE SRC SH2 DOMAIN COMPLEXED WITH PEPTIDE (SDPYANFK)
Descriptor:Proto-oncogene tyrosine-protein kinase Src, Peptide, CACODYLATE ION
Authors:Sonnenburg, E.D., Bilwes, A., Hunter, T., Noel, J.P.
Deposit date:2003-04-11
Release date:2003-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region.
Biochemistry, 42, 2003
1P15
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CRYSTAL STRUCTURE OF THE D2 DOMAIN OF RPTPA
Descriptor:Protein-tyrosine phosphatase alpha
Authors:Sonnenburg, E.D., Bilwes, A., Hunter, T., Noel, J.P.
Deposit date:2003-04-11
Release date:2003-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region.
Biochemistry, 42, 2003
1NMV
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SOLUTION STRUCTURE OF HUMAN PIN1
Descriptor:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Bayer, E., Goettsch, S., Mueller, J.W., Griewel, B., Guiberman, E., Mayr, L., Bayer, P.
Deposit date:2003-01-11
Release date:2003-08-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Analysis of the Mitotic Regulator hPin1 in Solution: INSIGHTS INTO DOMAIN ARCHITECTURE AND SUBSTRATE BINDING.
J.Biol.Chem., 278, 2003
1NMW
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SOLUTION STRUCTURE OF THE PPIASE DOMAIN OF HUMAN PIN1
Descriptor:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION
Authors:Bayer, E., Goettsch, S., Mueller, J.W., Griewel, B., Guiberman, E., Mayr, L., Bayer, P.
Deposit date:2003-01-12
Release date:2003-07-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Analysis of the Mitotic Regulator hPin1 in Solution: INSIGHTS INTO DOMAIN ARCHITECTURE AND SUBSTRATE BINDING.
J.Biol.Chem., 278, 2003
1YFO
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RECEPTOR PROTEIN TYROSINE PHOSPHATASE ALPHA, DOMAIN 1 FROM MOUSE
Descriptor:RECEPTOR PROTEIN TYROSINE PHOSPHATASE ALPHA
Authors:Bilwes, A.M., Noel, J.P.
Deposit date:1996-12-11
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for inhibition of receptor protein-tyrosine phosphatase-alpha by dimerization.
Nature, 382, 1996
2ITK
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HUMAN PIN1 BOUND TO D-PEPTIDE
Descriptor:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, D-Peptide, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL
Authors:Noel, J.P., Zhang, Y.
Deposit date:2006-10-19
Release date:2007-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural basis for high-affinity peptide inhibition of human Pin1.
Acs Chem.Biol., 2, 2007
2Q5A
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HUMAN PIN1 BOUND TO L-PEPTIDE
Descriptor:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Five residue peptide, 3,6,9,12,15,18-HEXAOXAICOSANE
Authors:Noel, J.P., Zhang, Y.
Deposit date:2007-05-31
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for high-affinity peptide inhibition of human Pin1.
Acs Chem.Biol., 2, 2007
3NG2
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CRYSTAL STRUCTURE OF THE RNF4 RING DOMAIN DIMER
Descriptor:RING finger protein 4, ZINC ION, SULFATE ION
Authors:Liew, C.W., Day, C.L.
Deposit date:2010-06-10
Release date:2010-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:RING domain dimerization is essential for RNF4 function
Biochem.J., 431, 2010
4UY9
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STRUCTURE OF MLK1 KINASE DOMAIN WITH LEUCINE ZIPPER 1
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9
Authors:Read, J.A., Brassington, C., Pollard, H.K., Phillips, C., Green, I., Overmann, R., Collier, M.
Deposit date:2014-08-29
Release date:2015-09-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Recurrent Mlk4 Loss-of-Function Mutations Suppress Jnk Signaling to Promote Colon Tumorigenesis.
Cancer Res., 76, 2016
4UYA
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STRUCTURE OF MLK4 KINASE DOMAIN WITH ATPGAMMAS
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE MLK4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MAGNESIUM ION
Authors:Read, J.A., Brassington, C., Pollard, H.K., Phillips, C., Green, I., Overmann, R., Collier, M.
Deposit date:2014-08-29
Release date:2015-09-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Recurrent Mlk4 Loss-of-Function Mutations Suppress Jnk Signaling to Promote Colon Tumorigenesis.
Cancer Res., 76, 2016
1FQ1
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CRYSTAL STRUCTURE OF KINASE ASSOCIATED PHOSPHATASE (KAP) IN COMPLEX WITH PHOSPHO-CDK2
Descriptor:CYCLIN-DEPENDENT KINASE INHIBITOR 3, CELL DIVISION PROTEIN KINASE 2, MAGNESIUM ION, ...
Authors:Song, H., Hanlon, N., Brown, N.R., Noble, M.E.M., Johnson, L.N., Barford, D.
Deposit date:2000-09-01
Release date:2001-05-09
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2.
Mol.Cell, 7, 2001