Author results

2GG4
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CP4 EPSP SYNTHASE (UNLIGANDED)
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase
Authors:Schonbrunn, E., Funke, T.
Deposit date:2006-03-23
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis for the herbicide resistance of Roundup Ready crops.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GG6
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CP4 EPSP SYNTHASE LIGANDED WITH S3P
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, SULFATE ION, SHIKIMATE-3-PHOSPHATE
Authors:Schonbrunn, E., Funke, T.
Deposit date:2006-03-23
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Molecular basis for the herbicide resistance of Roundup Ready crops.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GGA
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CP4 EPSP SYNTHASE LIGANDED WITH S3P AND GLYPHOSATE
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, SHIKIMATE-3-PHOSPHATE, GLYPHOSATE
Authors:Schonbrunn, E., Funke, T.
Deposit date:2006-03-23
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis for the herbicide resistance of Roundup Ready crops.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GGD
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CP4 EPSP SYNTHASE ALA100GLY LIGANDED WITH S3P AND GLYPHOSATE
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, SHIKIMATE-3-PHOSPHATE, GLYPHOSATE
Authors:Schonbrunn, E., Funke, T.
Deposit date:2006-03-23
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis for the herbicide resistance of Roundup Ready crops.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2PQ9
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E. COLI EPSPS LIGANDED WITH (R)-DIFLUOROMETHYL TETRAHEDRAL REACTION INTERMEDIATE ANALOG
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, (3R,4S,5R)-5-[(1R)-1-CARBOXY-2,2-DIFLUORO-1-(PHOSPHONOOXY)ETHOXY]-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID, FORMIC ACID
Authors:Healy-Fried, M.L., Funke, T., Han, H., Schonbrunn, E.
Deposit date:2007-05-01
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues.
Biochemistry, 46, 2007
2PQB
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CP4 EPSPS LIGANDED WITH (R)-DIFLUOROMETHYL TETRAHEDRAL INTERMEDIATE ANALOG
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, (3R,4S,5R)-5-[(1R)-1-CARBOXY-2,2-DIFLUORO-1-(PHOSPHONOOXY)ETHOXY]-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID
Authors:Healy-Fried, M.L., Funke, T., Han, H., Schonbrunn, E.
Deposit date:2007-05-01
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues.
Biochemistry, 46, 2007
2PQC
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CP4 EPSPS LIGANDED WITH (R)-PHOSPHONATE TETRAHEDRAL REACTION INTERMEDIATE ANALOG
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, [3R-[3A,4A,5B(R*)]]-5-(1-CARBOXY-1-PHOSPHONOETHOXY)-4-HYDROXY-3-(PHOSPHONOOXY)-1-CYCLOHEXENE-1-CARBOXYLIC ACID
Authors:Healy-Fried, M.L., Funke, T., Han, H., Schonbrunn, E.
Deposit date:2007-05-01
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues.
Biochemistry, 46, 2007
2PQD
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A100G CP4 EPSPS LIGANDED WITH (R)-DIFLUOROMETHYL TETRAHEDRAL REACTION INTERMEDIATE ANALOG
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, (3R,4S,5R)-5-[(1R)-1-CARBOXY-2,2-DIFLUORO-1-(PHOSPHONOOXY)ETHOXY]-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID
Authors:Healy-Fried, M.L., Funke, T., Han, H., Schonbrunn, E.
Deposit date:2007-05-01
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues.
Biochemistry, 46, 2007
3N56
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CRYSTAL STRUCTURE OF HUMAN INSULIN-DEGRADING ENZYME (IDE) IN COMPLEX WITH HUMAN B-TYPE NATRIURETIC PEPTIDE (BNP)
Descriptor:Insulin-degrading enzyme, Natriuretic peptides B, ZINC ION, ...
Authors:Funke, T., Guo, Q., Tang, W.-J.
Deposit date:2010-05-24
Release date:2010-11-17
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:Crystal Structure of human Insulin-degrading enzyme (IDE) in complex with human B-type natriuretic peptide (BNP)
To be Published
3N57
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CRYSTAL STRUCTURE OF HUMAN INSULIN-DEGRADING ENZYME (IDE) IN COMPLEX WITH HUMAN ATRIAL NATRIURETIC PEPTIDE (ANP)
Descriptor:Insulin-degrading enzyme, Atrial natriuretic factor, ZINC ION
Authors:Funke, T., Guo, Q., Tang, W.-J.
Deposit date:2010-05-24
Release date:2010-11-17
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Crystal Structure of human Insulin-degrading enzyme (IDE) in complex with human atrial natriuretic peptide (ANP)
To be Published
2AA9
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EPSP SYNTHASE LIGANDED WITH SHIKIMATE
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, FORMIC ACID
Authors:Priestman, M.A., Healy, M.L., Funke, T., Becker, A., Schonbrunn, E.
Deposit date:2005-07-13
Release date:2006-02-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate.
Febs Lett., 579, 2005
2AAY
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EPSP SYNTHASE LIGANDED WITH SHIKIMATE AND GLYPHOSATE
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, GLYPHOSATE, ...
Authors:Priestman, M.A., Healy, M.L., Funke, T., Becker, A.
Deposit date:2005-07-14
Release date:2006-02-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate.
Febs Lett., 579, 2005
3FJX
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E. COLI EPSP SYNTHASE (T97I) LIGANDED WITH S3P
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, SHIKIMATE-3-PHOSPHATE, FORMIC ACID
Authors:Schonbrunn, E.
Deposit date:2008-12-15
Release date:2009-02-17
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli.
J.Biol.Chem., 284, 2009
3FJZ
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E. COLI EPSP SYNTHASE (T97I) LIGANDED WITH S3P AND GLYPHOSATE
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, SERINE, N-(phosphonomethyl)glycine, ...
Authors:Schonbrunn, E.
Deposit date:2008-12-15
Release date:2009-02-17
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli.
J.Biol.Chem., 284, 2009
3FK0
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E. COLI EPSP SYNTHASE (TIPS MUTATION) LIGANDED WITH S3P
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, SHIKIMATE-3-PHOSPHATE, FORMIC ACID
Authors:Schonbrunn, E.
Deposit date:2008-12-15
Release date:2009-02-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli.
J.Biol.Chem., 284, 2009
3FK1
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E. COLI EPSP SYNTHASE (TIPS MUTATION) LIGANDED WITH S3P AND GLYPHOSATE
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, SHIKIMATE-3-PHOSPHATE, N-(phosphonomethyl)glycine, ...
Authors:Schonbrunn, E.
Deposit date:2008-12-15
Release date:2009-02-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli.
J.Biol.Chem., 284, 2009
3ELL
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STRUCTURE OF THE HEMOPHORE FROM PSEUDOMONAS AERUGINOSA (HASAP)
Descriptor:HasAp (Heme acquisition protein HasAp), PROTOPORPHYRIN IX CONTAINING FE
Authors:Schonbrunn, E., Rivera, M.
Deposit date:2008-09-22
Release date:2009-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural characterization of the hemophore HasAp from Pseudomonas aeruginosa: NMR spectroscopy reveals protein-protein interactions between Holo-HasAp and hemoglobin.
Biochemistry, 48, 2009
2QFQ
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E. COLI EPSP SYNTHASE PRO101LEU LIGANDED WITH S3P
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, SHIKIMATE-3-PHOSPHATE, FORMIC ACID
Authors:Schonbrunn, E., Healy-Fried, M.L.
Deposit date:2007-06-27
Release date:2007-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.
J.Biol.Chem., 282, 2007
2QFS
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E.COLI EPSP SYNTHASE PRO101SER LIGANDED WITH S3P
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, SHIKIMATE-3-PHOSPHATE, FORMIC ACID
Authors:Schonbrunn, E., Healy-Fried, M.L.
Deposit date:2007-06-28
Release date:2007-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.
J.Biol.Chem., 282, 2007
2QFT
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E.COLI EPSP SYNTHASE PRO101SER LIGANDED WITH S3P AND GLYPHOSATE
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, GLYPHOSATE, SHIKIMATE-3-PHOSPHATE, ...
Authors:Schonbrunn, E., Healy-Fried, M.L.
Deposit date:2007-06-28
Release date:2007-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.
J.Biol.Chem., 282, 2007
2QFU
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E.COLI EPSP SYNTHASE PRO101LEU LIGANDED WITH S3P AND GLYPHOSATE
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, GLYPHOSATE, SHIKIMATE-3-PHOSPHATE, ...
Authors:Schonbrunn, E., Healy-Fried, M.L.
Deposit date:2007-06-28
Release date:2007-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.
J.Biol.Chem., 282, 2007