2PQD
A100G CP4 EPSPS liganded with (R)-difluoromethyl tetrahedral reaction intermediate analog
Summary for 2PQD
Entry DOI | 10.2210/pdb2pqd/pdb |
Related | 1Q36 1X8R 1X8T 2GGA 2GGD 2PQ9 2PQB 2PQC |
Descriptor | 3-phosphoshikimate 1-carboxyvinyltransferase, (3R,4S,5R)-5-[(1R)-1-CARBOXY-2,2-DIFLUORO-1-(PHOSPHONOOXY)ETHOXY]-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID (3 entities in total) |
Functional Keywords | inside-out alpha/beta barrel, transferase |
Biological source | Agrobacterium sp. |
Cellular location | Cytoplasm (Probable): Q9R4E4 |
Total number of polymer chains | 1 |
Total formula weight | 47109.40 |
Authors | Healy-Fried, M.L.,Funke, T.,Han, H.,Schonbrunn, E. (deposition date: 2007-05-01, release date: 2008-03-11, Last modification date: 2023-08-30) |
Primary citation | Funke, T.,Healy-Fried, M.L.,Han, H.,Alberg, D.G.,Bartlett, P.A.,Schonbrunn, E. Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues. Biochemistry, 46:13344-13351, 2007 Cited by PubMed: 17958399DOI: 10.1021/bi701095u PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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