2PQD
A100G CP4 EPSPS liganded with (R)-difluoromethyl tetrahedral reaction intermediate analog
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| A | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| A | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
| A | 0004765 | molecular_function | shikimate kinase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0009635 | biological_process | response to herbicide |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE GG9 A 501 |
| Chain | Residue |
| A | LYS28 |
| A | ILE325 |
| A | ASP326 |
| A | LYS353 |
| A | GLU354 |
| A | ARG357 |
| A | ARG405 |
| A | HOH505 |
| A | HOH521 |
| A | HOH524 |
| A | HOH536 |
| A | SER29 |
| A | HOH609 |
| A | HOH625 |
| A | HOH765 |
| A | ARG33 |
| A | GLY100 |
| A | THR101 |
| A | ARG128 |
| A | SER173 |
| A | ALA174 |
| A | GLN175 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00210 |
| Chain | Residue | Details |
| A | ASP326 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00210 |
| Chain | Residue | Details |
| A | ARG128 | |
| A | GLN175 | |
| A | ARG357 | |
| A | ARG405 | |
| A | LYS28 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16916934, ECO:0007744|PDB:2GG6, ECO:0007744|PDB:2GGA, ECO:0007744|PDB:2GGD |
| Chain | Residue | Details |
| A | ALA174 | |
| A | ASP326 | |
| A | LYS353 | |
| A | SER29 | |
| A | SER173 | |
| A | ARG33 |
