2AAY

EPSP synthase liganded with shikimate and glyphosate

Summary for 2AAY

Entry DOI	10.2210/pdb2aay/pdb
Related	1G6S 1G6T 1MI4 1Q36 1X8R 1X8T
Descriptor	3-phosphoshikimate 1-carboxyvinyltransferase, (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, GLYPHOSATE, ... (5 entities in total)
Functional Keywords	inside-out alpha/beta barrel, transferase
Biological source	Escherichia coli
Cellular location	Cytoplasm : P0A6D3
Total number of polymer chains	1
Total formula weight	46900.07
Authors	Priestman, M.A.,Healy, M.L.,Funke, T.,Becker, A. (deposition date: 2005-07-14, release date: 2006-02-14, Last modification date: 2023-08-23)
Primary citation	Priestman, M.A.,Healy, M.L.,Funke, T.,Becker, A. Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate. Febs Lett., 579:5773-5780, 2005 Cited by PubMed: 16225867 DOI: 10.1016/j.febslet.2005.09.066 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation