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5AEA
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CRYSTAL STRUCTURE OF HUMAN NCAM DOMAIN 1
Descriptor:NEURAL CELL ADHESION MOLECULE 1, CITRATE ANION
Authors:Kvansakul, M., Griffiths, K., Foley, M.
Deposit date:2015-08-27
Release date:2016-04-13
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:I-Bodies, Human Single Domain Antibodies that Antagonize Chemokine Receptor Cxcr4.
J.Biol.Chem., 291, 2016
5V37
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CRYSTAL STRUCTURE OF SMYD3 WITH SAM AND EPZ028862
Descriptor:Histone-lysine N-methyltransferase SMYD3, ZINC ION, S-ADENOSYLMETHIONINE, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2017-03-06
Release date:2018-03-07
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:SMYD Enzyme Disruption by Gene Ablation and Small Molecule Inhibitors Confer Discordant Phenotypes in Cancer Cells
to be published
5V3H
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CRYSTAL STRUCTURE OF SMYD2 WITH SAM AND EPZ033294
Descriptor:N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ZINC ION, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2017-03-07
Release date:2018-04-25
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:SMYD Enzyme Disruption by Gene Ablation and Small Molecule Inhibitors Confer Discordant Phenotypes in Cancer Cells
to be published
1HN6
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SOLUTION STRUCTURE OF PLASMODIUM FALCIPARUM APICAL MEMBRANE ANTIGEN 1 (RESIDUES 436-545)
Descriptor:APICAL MEMBRANE ANTIGEN 1
Authors:Nair, M.
Deposit date:2000-12-07
Release date:2002-10-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of domain III of the blood-stage malaria vaccine candidate, Plasmodium falciparum apical membrane antigen 1 (AMA1).
J.Mol.Biol., 322, 2002
5CCL
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CRYSTAL STRUCTURE OF SMYD3 WITH SAM AND OXINDOLE COMPOUND
Descriptor:Histone-lysine N-methyltransferase SMYD3, ZINC ION, S-ADENOSYLMETHIONINE, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2015-07-02
Release date:2015-09-09
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor.
Acs Med.Chem.Lett., 7, 2016
5CCM
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CRYSTAL STRUCTURE OF SMYD3 WITH SAM AND EPZ030456
Descriptor:Histone-lysine N-methyltransferase SMYD3, ZINC ION, S-ADENOSYLMETHIONINE, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2015-07-02
Release date:2015-09-09
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor.
Acs Med.Chem.Lett., 7, 2016
2Q8A
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STRUCTURE OF THE MALARIA ANTIGEN AMA1 IN COMPLEX WITH A GROWTH-INHIBITORY ANTIBODY
Descriptor:Apical membrane antigen 1, 1F9 light chain, 1F9 heavy chain
Authors:Gupta, A., Murphy, V.J., Anders, R.F., Batchelor, A.H.
Deposit date:2007-06-10
Release date:2007-10-09
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody.
PLoS Pathog., 3, 2007
2Q8B
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STRUCTURE OF THE MALARIA ANTIGEN AMA1 IN COMPLEX WITH A GROWTH-INHIBITORY ANTIBODY
Descriptor:Apical membrane antigen 1, 1F9 light chain, 1F9 heavy chain
Authors:Gupta, A., Murphy, V.J., Anders, R.F., Batchelor, A.H.
Deposit date:2007-06-10
Release date:2007-10-09
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Malaria Antigen AMA1 in Complex with a Growth-Inhibitory Antibody
Plos Pathog., 3, 2007
2YWY
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STRUCTURE OF NEW ANTIGEN RECEPTOR VARIABLE DOMAIN FROM SHARKS
Descriptor:new antigen receptor variable domain
Authors:Streltsov, V.A.
Deposit date:2007-04-23
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Shark IgNAR antibody mimotopes target a murine immunoglobulin through extended CDR3 loop structures
Proteins, 71, 2007
2YWZ
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STRUCTURE OF NEW ANTIGEN RECEPTOR VARIABLE DOMAIN FROM SHARKS
Descriptor:new antigen receptor variable domain
Authors:Streltsov, V.A.
Deposit date:2007-04-23
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Shark IgNAR antibody mimotopes target a murine immunoglobulin through extended CDR3 loop structures
Proteins, 71, 2007
2Z8V
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STRUCTURE OF AN IGNAR-AMA1 COMPLEX
Descriptor:Apical membrane antigen 1, New antigen receptor variable domain
Authors:Streltsov, V.A., Henderson, K.A., Batchelor, A.H., Coley, A.M., Nuttall, S.D.
Deposit date:2007-09-11
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of an IgNAR-AMA1 Complex: Targeting a Conserved Hydrophobic Cleft Broadens Malarial Strain Recognition
Structure, 15, 2007
2Z8W
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STRUCTURE OF AN IGNAR-AMA1 COMPLEX
Descriptor:Apical membrane antigen 1, New antigen receptor variable domain
Authors:Streltsov, V.A., Henderson, K.A., Batchelor, A.H., Coley, A.M., Nuttall, S.D.
Deposit date:2007-09-11
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of an IgNAR-AMA1 Complex: Targeting a Conserved Hydrophobic Cleft Broadens Malarial Strain Recognition
Structure, 15, 2007
1PSM
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SOLUTION STRUCTURE OF A POLYPEPTIDE CONTAINING FOUR HEPTAD REPEATS FROM A MEROZOITE SURFACE ANTIGEN OF PLASMODIUM FALCIPARUM
Descriptor:SPAM-H1
Authors:Mulhern, T.D., Norton, R.S.
Deposit date:1994-12-01
Release date:1995-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a polypeptide containing four heptad repeat units from a merozoite surface antigen of Plasmodium falciparum.
Biochemistry, 34, 1995
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