Author results

9HVP
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DESIGN, ACTIVITY AND 2.8 ANGSTROMS CRYSTAL STRUCTURE OF A C2 SYMMETRIC INHIBITOR COMPLEXED TO HIV-1 PROTEASE
分子名称:HIV-1 PROTEASE, benzyl [(1R,4S,6S,9R)-4,6-dibenzyl-5-hydroxy-1,9-bis(1-methylethyl)-2,8,11-trioxo-13-phenyl-12-oxa-3,7,10-triazatridec-1-yl]carbamate
著者Neidhart, D.J., Erickson, J.
登録日1990-11-06
公開日1992-04-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease.
Science, 249, 1990
1RWJ
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C7-TYPE THREE-HEME CYTOCHROME DOMAIN
分子名称:Cytochrome c family protein, PROTOPORPHYRIN IX CONTAINING FE
著者Pokkuluri, P.R., Londer, Y.Y., Duke, N.E.C., Erickson, J., Pessanha, M., Salgueiro, C.A., Schiffer, M.
登録日2003-12-16
公開日2004-08-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of a novel c7-type three-heme cytochrome domain from a multidomain cytochrome c polymer.
Protein Sci., 13, 2004
4FE6
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CRYSTAL STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH AN ENAMINO-OXINDOLE INHIBITOR
分子名称:HIV protease, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[({(3Z)-3-[1-(methylamino)ethylidene]-2-oxo-2,3-dihydro-1H-indol-5-yl}sulfonyl)(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate
著者Silva, A.M., Eissenstat, M., Guerassina, T., Gulnik, S., Afonina, E., Yu, B., Erickson, J., Ludke, D., Yokoe, H.
登録日2012-05-29
公開日2012-07-18
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Enamino-oxindole HIV protease inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
1LYW
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CATHEPSIN D AT PH 7.5
分子名称:CATHEPSIN D, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
著者Lee, A.Y., Gulnik, S.V., Erickson, J.W.
登録日1998-06-30
公開日1999-07-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Conformational switching in an aspartic proteinase.
Nat.Struct.Biol., 5, 1998
1LYA
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CRYSTAL STRUCTURES OF NATIVE AND INHIBITED FORMS OF HUMAN CATHEPSIN D: IMPLICATIONS FOR LYSOSOMAL TARGETING AND DRUG DESIGN
分子名称:CATHEPSIN D, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Baldwin, E.T., Bhat, T.N., Gulnik, S., Erickson, J.W.
登録日1993-04-22
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.
Proc.Natl.Acad.Sci.USA, 90, 1993
1LYB
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CRYSTAL STRUCTURES OF NATIVE AND INHIBITED FORMS OF HUMAN CATHEPSIN D: IMPLICATIONS FOR LYSOSOMAL TARGETING AND DRUG DESIGN
分子名称:CATHEPSIN D, PEPSTATIN, N-ACETYL-D-GLUCOSAMINE, ...
著者Baldwin, E.T., Bhat, T.N., Gulnik, S., Erickson, J.W.
登録日1993-04-22
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.
Proc.Natl.Acad.Sci.USA, 90, 1993
1PSA
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STRUCTURE OF A PEPSIN(SLASH)RENIN INHIBITOR COMPLEX REVEALS A NOVEL CRYSTAL PACKING INDUCED BY MINOR CHEMICAL ALTERATIONS IN THE INHIBITOR
分子名称:PEPSIN A, N-(ethoxycarbonyl)-L-leucyl-N-[(1R,2S,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-leucinamide
著者Chen, L., Abad-Zapatero, C.
登録日1991-10-22
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of a pepsin/renin inhibitor complex reveals a novel crystal packing induced by minor chemical alterations in the inhibitor.
Acta Crystallogr.,Sect.B, 48, 1992
3PEP
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REVISED 2.3 ANGSTROMS STRUCTURE OF PORCINE PEPSIN. EVIDENCE FOR A FLEXIBLE SUBDOMAIN
分子名称:PEPSIN, ETHANOL
著者Abad-Zapatero, C., Erickson, J.W.
登録日1989-10-24
公開日1990-04-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Revised 2.3 A structure of porcine pepsin: evidence for a flexible subdomain
Proteins, 8, 1990
3OUE
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STRUCTURE OF C-TERMINAL HEXAHEME FRAGMENT OF GSU1996
分子名称:Cytochrome c family protein, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE
著者Pokkuluri, P.R., Schiffer, M.
登録日2010-09-14
公開日2010-12-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of a novel dodecaheme cytochrome c from Geobacter sulfurreducens reveals an extended 12nm protein with interacting hemes.
J.Struct.Biol., 174, 2011
3OUQ
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STRUCTURE OF N-TERMINAL HEXAHEME FRAGMENT OF GSU1996
分子名称:Cytochrome c family protein, PROTOPORPHYRIN IX CONTAINING FE
著者Pokkuluri, P.R., Schiffer, M.
登録日2010-09-15
公開日2010-12-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a novel dodecaheme cytochrome c from Geobacter sulfurreducens reveals an extended 12nm protein with interacting hemes.
J.Struct.Biol., 174, 2011
3OV0
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STRUCTURE OF DODECAHEME CYTOCHROME C GSU1996
分子名称:Cytochrome c family protein, PROTOPORPHYRIN IX CONTAINING FE
著者Pokkuluri, P.R., Schiffer, M.
登録日2010-09-15
公開日2010-12-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of a novel dodecaheme cytochrome c from Geobacter sulfurreducens reveals an extended 12nm protein with interacting hemes.
J.Struct.Biol., 174, 2011
3H33
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PPCC, A CYTOCHROME C7 FROM GEOBACTER SULFURREDUCENS
分子名称:Cytochrome c7, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Pokkuluri, P.R., Schiffer, M.
登録日2009-04-15
公開日2009-12-29
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural characterization of a family of cytochromes c(7) involved in Fe(III) respiration by Geobacter sulfurreducens.
Biochim.Biophys.Acta, 1797, 2010
3H34
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PPCE, A CYTOCHROME C7 FROM GEOBACTER SULFURREDUCENS
分子名称:Cytochrome c7, PROTOPORPHYRIN IX CONTAINING FE
著者Pokkuluri, P.R., Schiffer, M.
登録日2009-04-15
公開日2009-12-29
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural characterization of a family of cytochromes c(7) involved in Fe(III) respiration by Geobacter sulfurreducens.
Biochim.Biophys.Acta, 1797, 2010
3H4N
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PPCD, A CYTOCHROME C7 FROM GEOBACTER SULFURREDUCENS
分子名称:Cytochrome c7, PROTOPORPHYRIN IX CONTAINING FE
著者Pokkuluri, P.R., Schiffer, M.
登録日2009-04-20
公開日2009-12-29
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural characterization of a family of cytochromes c(7) involved in Fe(III) respiration by Geobacter sulfurreducens.
Biochim.Biophys.Acta, 1797, 2010
4PHV
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X-RAY CRYSTAL STRUCTURE OF THE HIV PROTEASE COMPLEX WITH L-700,417, AN INHIBITOR WITH PSEUDO C2 SYMMETRY
分子名称:HIV-1 PROTEASE, N,N-BIS(2-HYDROXY-1-INDANYL)-2,6- DIPHENYLMETHYL-4-HYDROXY-1,7-HEPTANDIAMIDE
著者Bone, R.
登録日1991-10-04
公開日1993-10-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-Ray Crystal Structure of the HIV Protease Complex with L-700,417, an Inhibitor with Pseudo C2 Symmetry
J.Am.Chem.Soc., 113, 1991