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6L92
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BU of 6l92 by Molmil
A basket type G-quadruplex in WNT DNA promoter
Descriptor: DNA (5'-D(*GP*GP*GP*CP*CP*AP*CP*CP*GP*GP*GP*CP*AP*GP*TP*GP*GP*GP*CP*GP*GP*G)-3')
Authors:Wang, Z.F, Li, M.H, Chu, I.T, Winnerdy, F.R, Phan, A.T, Chang, T.C.
Deposit date:2019-11-08
Release date:2019-12-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter.
Nucleic Acids Res., 48, 2020
6L8M
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BU of 6l8m by Molmil
WNT DNA promoter mutant G-quadruplex
Descriptor: DNA (5'-D(*GP*GP*GP*TP*CP*AP*CP*CP*GP*GP*GP*CP*AP*GP*TP*GP*GP*GP*CP*GP*GP*G)-3')
Authors:Wang, Z.F, Li, M.H, Chu, I.T, Winnerdy, F.R, Phan, A.T, Chang, T.C.
Deposit date:2019-11-06
Release date:2019-12-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter.
Nucleic Acids Res., 48, 2020
6NLH
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BU of 6nlh by Molmil
Structure of human triose phosphate isomerase R189A
Descriptor: BROMIDE ION, PHOSPHATE ION, SODIUM ION, ...
Authors:Richards, K.R, Roland, B.P, Palladino, M.J, VanDemark, A.P.
Deposit date:2019-01-08
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
Biochim Biophys Acta Mol Basis Dis, 1865, 2019
8TH5
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BU of 8th5 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein P13L mutant
Descriptor: Nucleoprotein, Ras GTPase-activating protein-binding protein 1
Authors:Hughes, M.P, Taylor, J.P.
Deposit date:2023-07-13
Release date:2024-03-20
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH1
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BU of 8th1 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein D3L mutant
Descriptor: Nucleoprotein, Ras GTPase-activating protein-binding protein 1
Authors:Hughes, M.P, Taylor, J.P.
Deposit date:2023-07-13
Release date:2023-12-27
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH7
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BU of 8th7 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide
Descriptor: Caprin-1, Ras GTPase-activating protein-binding protein 1
Authors:Hughes, M.P, Taylor, J.P.
Deposit date:2023-07-14
Release date:2024-03-20
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH6
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BU of 8th6 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to USP10 peptide
Descriptor: 1,2-ETHANEDIOL, Ras GTPase-activating protein-binding protein 1, Ubiquitin carboxyl-terminal hydrolase 10
Authors:Hughes, M.P, Taylor, J.P.
Deposit date:2023-07-14
Release date:2024-03-20
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
6JJ0
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BU of 6jj0 by Molmil
NMR structure of the 1:1 complex of a carbazole derivative BMVC bound to c-MYC G-quadruplex
Descriptor: 3,6-bis[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]-9H-carbazole, MycG4
Authors:Liu, W, Lin, C, Yang, D.
Deposit date:2019-02-24
Release date:2019-10-30
Last modified:2022-03-23
Method:SOLUTION NMR
Cite:Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition.
Nucleic Acids Res., 47, 2019
6O2L
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BU of 6o2l by Molmil
NMR structure of the 2:1 complex of a carbazole derivative BMVC bound to c-MYC G-quadruplex
Descriptor: 3,6-bis[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]-9H-carbazole, DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3')
Authors:Lin, C, Liu, W, Yang, D.
Deposit date:2019-02-24
Release date:2019-10-23
Last modified:2020-05-06
Method:SOLUTION NMR
Cite:Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition.
Nucleic Acids Res., 47, 2019

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