Author results

4FE1
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IMPROVING THE ACCURACY OF MACROMOLECULAR STRUCTURE REFINEMENT AT 7 A RESOLUTION
Descriptor:Photosystem I P700 chlorophyll a apoprotein A1, Photosystem I P700 chlorophyll a apoprotein A2, Photosystem I iron-sulfur center, ...
Authors:Fromme, R., Adams, P.D., Fromme, P., Levitt, M., Schroeder, G.F., Brunger, A.T.
Deposit date:2012-05-29
Release date:2012-08-15
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (4.9228 Å)
Cite:Improving the accuracy of macromolecular structure refinement at 7 A resolution.
Structure, 20, 2012
1BAF
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2.9 ANGSTROMS RESOLUTION STRUCTURE OF AN ANTI-DINITROPHENYL-SPIN-LABEL MONOCLONAL ANTIBODY FAB FRAGMENT WITH BOUND HAPTEN
Descriptor:IGG1-KAPPA AN02 FAB (LIGHT CHAIN), IGG1-KAPPA AN02 FAB (HEAVY CHAIN), N-(2-AMINO-ETHYL)-4,6-DINITRO-N'-(2,2,6,6-TETRAMETHYL-1-OXY-PIPERIDIN-4-YL)-BENZENE-1,3-DIAMINE
Authors:Leahy, D.J., Brunger, A.T., Fox, R.O., Hynes, T.R.
Deposit date:1992-01-16
Release date:1994-01-31
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:2.9 A resolution structure of an anti-dinitrophenyl-spin-label monoclonal antibody Fab fragment with bound hapten.
J.Mol.Biol., 221, 1991
2ISE
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BOTULINUM NEUROTOXIN A LIGHT CHAIN WT CRYSTAL FORM A
Descriptor:Neurotoxin BoNT/A, ZINC ION
Authors:Brunger, A.T., Stegmann, C.M.
Deposit date:2006-10-17
Release date:2006-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
J.Biol.Chem., 282, 2007
2ISG
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BOTULINUM NEUROTOXIN A LIGHT CHAIN WT CRYSTAL FORM B
Descriptor:Neurotoxin BoNT/A, ZINC ION, NICKEL (II) ION
Authors:Brunger, A.T., Stegmann, C.M.
Deposit date:2006-10-17
Release date:2006-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
J.Biol.Chem., 282, 2007
2ISH
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BOTULINUM NEUROTOXIN A LIGHT CHAIN WT CRYSTAL FORM C
Descriptor:Neurotoxin BoNT/A, ZINC ION
Authors:Brunger, A.T., Stegmann, C.M.
Deposit date:2006-10-17
Release date:2006-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
J.Biol.Chem., 282, 2007
3TX8
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CRYSTAL STRUCTURE OF A SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (ARGE) FROM CORYNEBACTERIUM GLUTAMICUM ATCC 13032 AT 2.97 A RESOLUTION
Descriptor:Succinyl-diaminopimelate desuccinylase, PHOSPHATE ION, CHLORIDE ION
Authors:Joint Center for Structural Genomics (JCSG), Brunger, A.T., Terwilliger, T.C., Read, R.J., Adams, P.D., Levitt, M., Schroder, G.F.
Deposit date:2011-09-22
Release date:2011-10-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.972 Å)
Cite:Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum.
Acta Crystallogr.,Sect.D, 68, 2012
3CF1
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STRUCTURE OF P97/VCP IN COMPLEX WITH ADP/ADP.ALFX
Descriptor:Transitional endoplasmic reticulum ATPase, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE
Authors:Davies, J.M., Delabarre, B., Brunger, A.T., Weis, W.I.
Deposit date:2008-03-01
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change.
Structure, 16, 2008
3CF2
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STRUCTURE OF P97/VCP IN COMPLEX WITH ADP/AMP-PNP
Descriptor:Transitional endoplasmic reticulum ATPase, ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Davies, J.M., Delabarre, B., Brunger, A.T., Weis, W.I.
Deposit date:2008-03-01
Release date:2008-04-22
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change.
Structure, 16, 2008
3CF3
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STRUCTURE OF P97/VCP IN COMPLEX WITH ADP
Descriptor:Transitional endoplasmic reticulum ATPase, ADENOSINE-5'-DIPHOSPHATE
Authors:Davies, J.M., Delabarre, B., Brunger, A.T., Weis, W.I.
Deposit date:2008-03-01
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.25 Å)
Cite:Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change.
Structure, 16, 2008
1GTO
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HIGH RESOLUTION STRUCTURE OF A HYPERSTABLE HELICAL BUNDLE PROTEIN MUTANT
Descriptor:ROP
Authors:Agrawal, V., Predki, P., Regan, L., Brunger, A.T.
Deposit date:1996-04-23
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Amino-acid substitutions in a surface turn modulate protein stability.
Nat.Struct.Biol., 3, 1996
1BBG
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RAGWEED POLLEN ALLERGEN FROM AMBROSIA TRIFIDA V, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:POLLEN ALLERGEN 5
Authors:Warren, G.L., Tuner, C.J., Petsko, G.A., Brunger, A.T.
Deposit date:1998-04-24
Release date:1998-06-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Highly Precise Solution 1H NMR Structure of Ragweed Allergen Amb. T. V
To be Published
1CE5
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BOVINE PANCREAS BETA-TRYPSIN IN COMPLEX WITH BENZAMIDINE
Descriptor:PROTEIN (TRYPSIN), CALCIUM ION, CHLORIDE ION, ...
Authors:Ota, N., Stroupe, C., Ferreira-Da-Silva, J.M.S., Shah, S.S., Mares-Guia, M., Brunger, A.T.
Deposit date:1999-03-16
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Non-Boltzmann thermodynamic integration (NBTI) for macromolecular systems: relative free energy of binding of trypsin to benzamidine and benzylamine.
Proteins, 37, 1999
1DQV
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CRYSTAL STRUCTURE OF SYNAPTOTAGMIN III C2A/C2B
Descriptor:SYNAPTOTAGMIN III, MAGNESIUM ION, SULFATE ION
Authors:Sutton, R.B., Ernst, J.A., Brunger, A.T.
Deposit date:2000-01-05
Release date:2000-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interaction.
J.Cell Biol., 147, 1999
1EDU
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CRYSTAL STRUCTURE OF THE ENTH DOMAIN OF RAT EPSIN 1
Descriptor:EH domain binding protein EPSIN, 1,2-ETHANEDIOL
Authors:Hyman, J.H., Chen, H., Decamilli, P., Brunger, A.T.
Deposit date:2000-01-28
Release date:2000-05-10
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZF).
J.Cell Biol., 149, 2000
1EXR
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THE 1.0 ANGSTROM CRYSTAL STRUCTURE OF CA+2 BOUND CALMODULIN
Descriptor:CALMODULIN, CALCIUM ION
Authors:Wilson, M.A., Brunger, A.T.
Deposit date:2000-05-03
Release date:2000-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:The 1.0 A crystal structure of Ca(2+)-bound calmodulin: an analysis of disorder and implications for functionally relevant plasticity
J.Mol.Biol., 301, 2000
1F4M
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P3(2) CRYSTAL STRUCTURE OF ALA2ILE2-6, A VERSION OF ROP WITH A REPACKED HYDROPHOBIC CORE AND A NEW FOLD.
Descriptor:ROP ALA2ILE2-6, CALCIUM ION
Authors:Willis, M.A., Bishop, B., Regan, L., Brunger, A.T.
Deposit date:2000-06-08
Release date:2001-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Dramatic structural and thermodynamic consequences of repacking a protein's hydrophobic core.
Structure Fold.Des., 8, 2000
1F4N
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C2 CRYSTAL STRUCTURE OF ALA2ILE2-6, A VERSION OF ROP WITH A REPACKED HYDROPHOBIC CORE AND A NEW FOLD.
Descriptor:ROP ALA2ILE2-6, CALCIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Willis, M.A., Bishop, B., Regan, L., Brunger, A.T.
Deposit date:2000-06-08
Release date:2001-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Dramatic structural and thermodynamic consequences of repacking a protein's hydrophobic core.
Structure Fold.Des., 8, 2000
1G16
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CRYSTAL STRUCTURE OF SEC4-GDP
Descriptor:RAS-RELATED PROTEIN SEC4, COBALT (II) ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Stroupe, C., Brunger, A.T.
Deposit date:2000-10-10
Release date:2000-12-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of a Rab protein in its inactive and active conformations.
J.Mol.Biol., 304, 2000
1G17
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CRYSTAL STRUCTURE OF SEC4-GUANOSINE-5'-(BETA,GAMMA)-IMIDOTRIPHOSPHATE
Descriptor:RAS-RELATED PROTEIN SEC4, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Stroupe, C., Brunger, A.T.
Deposit date:2000-10-10
Release date:2000-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of a Rab protein in its inactive and active conformations.
J.Mol.Biol., 304, 2000
1GBN
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HUMAN ORNITHINE AMINOTRANSFERASE COMPLEXED WITH THE NEUROTOXIN GABACULINE
Descriptor:ORNITHINE AMINOTRANSFERASE, 3-AMINOBENZOIC ACID, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Shah, S.A., Shen, B.W., Brunger, A.T.
Deposit date:1997-05-29
Release date:1998-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human ornithine aminotransferase complexed with L-canaline and gabaculine: structural basis for substrate recognition.
Structure, 5, 1997
1JXM
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CRYSTAL STRUCTURE OF THE GMP BOUND SH3-HOOK-GK FRAGMENT OF PSD-95
Descriptor:POSTSYNAPTIC DENSITY PROTEIN, GUANOSINE-5'-MONOPHOSPHATE, GUANIDINE, ...
Authors:Tavares, G.A., Panepucci, E.H., Brunger, A.T.
Deposit date:2001-09-07
Release date:2002-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95.
Mol.Cell, 8, 2001
1JXO
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CRYSTAL STRUCTURE OF THE SH3-HOOK-GK FRAGMENT OF PSD-95
Descriptor:postsynaptic density protein
Authors:Tavares, G.A., Panepucci, E.H., Brunger, A.T.
Deposit date:2001-09-07
Release date:2002-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95.
Mol.Cell, 8, 2001
1KWA
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HUMAN CASK/LIN-2 PDZ DOMAIN
Descriptor:HCASK/LIN-2 PROTEIN, SULFATE ION
Authors:Daniels, D.L., Cohen, A.R., Anderson, J.M., Brunger, A.T.
Deposit date:1998-01-16
Release date:1998-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition
Nat.Struct.Biol., 5, 1998
1N0Y
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CRYSTAL STRUCTURE OF PB-BOUND CALMODULIN
Descriptor:Calmodulin, LEAD (II) ION, CACODYLATE ION, ...
Authors:Wilson, M.A., Brunger, A.T.
Deposit date:2002-10-15
Release date:2003-09-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Domain flexibility in the 1.75 A resolution structure of Pb2+-calmodulin.
Acta Crystallogr.,Sect.D, 59, 2003
1N7S
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HIGH RESOLUTION STRUCTURE OF A TRUNCATED NEURONAL SNARE COMPLEX
Descriptor:vesicle-associated membrane protein 2, Syntaxin 1A, SNAP-25A, ...
Authors:Ernst, J.A., Brunger, A.T.
Deposit date:2002-11-16
Release date:2002-12-27
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High Resolution Structure, Stability, and Synaptotagmin Binding of a Truncated Neuronal SNARE Complex
J.Biol.Chem., 278, 2003