Author results

6M6Z
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A DE NOVO DESIGNED TRANSMEMBRANE NANOPORE, TMH4C4
Descriptor:TMH4C4
Authors:Lu, P., Xu, C., Reggiano, G., Xu, Q., DiMaio, F., Baker, D.
Deposit date:2020-03-16
Release date:2020-06-24
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Computational Design of Transmembrane Pores
Nature, 2020
6TJ1
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED HEXAMERIC HELICAL-BUNDLE PROTEIN
Descriptor:De novo designed WSHC6, purification tag
Authors:Xu, C., Pei, X.Y., Luisi, B.F., Baker, D.
Deposit date:2019-11-23
Release date:2020-04-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Computational Design of Transmembrane Pores
Nature, 2020
6TMS
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED HEXAMERIC HELICAL-BUNDLE PROTEIN
Descriptor:a novel designed pore protein, affinity purification tag, SULFATE ION
Authors:Xu, C., Pei, X.Y., Luisi, B.F., Baker, D.
Deposit date:2019-12-05
Release date:2020-04-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Computational Design of Transmembrane Pores
Nature, 2020
6NX2
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CRYSTAL STRUCTURE OF COMPUTATIONALLY DESIGNED PROTEIN AAA
Descriptor:Design construct AAA, BROMIDE ION
Authors:Wei, K.Y., Bick, M.J.
Deposit date:2019-02-07
Release date:2020-04-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NXM
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CRYSTAL STRUCTURE OF COMPUTATIONALLY DESIGNED PROTEIN XAA_GVDQ
Descriptor:Design construct XAA_GVDQ
Authors:Wei, K.Y., Bick, M.J.
Deposit date:2019-02-08
Release date:2020-04-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NY8
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CRYSTAL STRUCTURE OF COMPUTATIONALLY DESIGNED PROTEIN XAA_GVDQ WITH CALCIUM
Descriptor:Design construct XAA_GVDQ, CHLORIDE ION, CALCIUM ION
Authors:Wei, K.Y., Bick, M.J.
Deposit date:2019-02-11
Release date:2020-04-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NYE
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CRYSTAL STRUCTURE OF COMPUTATIONALLY DESIGNED PROTEIN XAX
Descriptor:Design construct XAX
Authors:Wei, K.Y., Bick, M.J.
Deposit date:2019-02-11
Release date:2020-04-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NYI
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CRYSTAL STRUCTURE OF COMPUTATIONALLY DESIGNED PROTEIN XXA
Descriptor:Design construct XXA
Authors:Wei, K.Y., Bick, M.J.
Deposit date:2019-02-11
Release date:2020-04-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NYK
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CRYSTAL STRUCTURE OF COMPUTATIONALLY DESIGNED PROTEIN XAX_GGDQ
Descriptor:Design construct XAX_GGDQ
Authors:Wei, K.Y., Bick, M.J.
Deposit date:2019-02-11
Release date:2020-04-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NZ1
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CRYSTAL STRUCTURE OF COMPUTATIONALLY DESIGNED PROTEIN XXA_GVDQ
Descriptor:Design construct XXA_GVDQ
Authors:Wei, K.Y., Bick, M.J.
Deposit date:2019-02-12
Release date:2020-04-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NZ3
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CRYSTAL STRUCTURE OF COMPUTATIONALLY DESIGNED PROTEIN XAA_GGHN
Descriptor:Design construct XAA_GGHN, CHLORIDE ION
Authors:Wei, K.Y., Bick, M.J.
Deposit date:2019-02-12
Release date:2020-04-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6O0C
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NMR ENSEMBLE OF COMPUTATIONALLY DESIGNED PROTEIN XAA_GVDQ MUTANT M4L
Descriptor:Design construct XAA_GVDQ mutant M4L
Authors:Wei, K.Y., Moschidi, D., Nerli, S., Sgourakis, N., Baker, D.
Deposit date:2019-02-15
Release date:2020-04-22
Method:SOLUTION NMR
Cite:Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6O0I
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NMR ENSEMBLE OF COMPUTATIONALLY DESIGNED PROTEIN XAA
Descriptor:Design construct XAA
Authors:Wei, K.Y., Moschidi, D., Nerli, S., Sgourakis, N., Baker, D.
Deposit date:2019-02-16
Release date:2020-04-22
Method:SOLUTION NMR
Cite:Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WI5
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DE NOVO DESIGNED PROTEIN FOLDIT4
Descriptor:De novo designed protein Foldit4
Authors:Bera, A.K., Koepnick, B., Boykov, A., Baker, D.
Deposit date:2020-04-08
Release date:2020-04-22
Last modified:2020-05-20
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:De novo designed protein Foldit4
To Be Published
6W2Q
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JUNCTION 34, DHR53-DHR4
Descriptor:Junction 34, CALCIUM ION
Authors:Bick, M.J., Brunette, T.J., Baker, D.
Deposit date:2020-03-08
Release date:2020-04-15
Last modified:2020-04-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W2R
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JUNCTION 19, DHR54-DHR79
Descriptor:Junction 19 DHR54-DHR79
Authors:Bick, M.J., Brunette, T.J., Baker, D.
Deposit date:2020-03-08
Release date:2020-04-15
Last modified:2020-04-29
Method:X-RAY DIFFRACTION (2.344 Å)
Cite:Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W2V
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JUNCTION 23, DHR14-DHR18
Descriptor:Junction 23 DHR14-DHR18
Authors:Bick, M.J., Brunette, T.J., Baker, D.
Deposit date:2020-03-08
Release date:2020-04-15
Last modified:2020-04-29
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W2W
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JUNCTION 24, DHR14-DHR18
Descriptor:Junction 24 DHR14-DHR18
Authors:Bick, M.J., Brunette, T.J., Baker, D.
Deposit date:2020-03-08
Release date:2020-04-15
Last modified:2020-04-29
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W3D
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RD1NTF2_05 WITH LONG SHEET
Descriptor:Rd1NTF2_05
Authors:Bick, M.J., Basanta, B., Baker, D.
Deposit date:2020-03-09
Release date:2020-04-15
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:A generative algorithm for de novo design of proteins with diverse pockets
To Be Published
6W3F
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RD1NTF2_05_I64F_A80G_T94P_D101K_L106W
Descriptor:Rd1NTF2_05_I64F_A80G_T94P_D101K_L106W
Authors:Bick, M.J., Basanta, B., Baker, D.
Deposit date:2020-03-09
Release date:2020-04-15
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:A generative algorithm for de novo design of proteins with diverse pockets
To Be Published
6W3G
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RD1NTF2_04 WITH LONG SHEET
Descriptor:Rd1NTF2_04
Authors:Bick, M.J., Basanta, B., Baker, D.
Deposit date:2020-03-09
Release date:2020-04-15
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:A generative algorithm for de novo design of proteins with diverse pockets
To Be Published
6W3W
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A GENERATIVE ALGORITHM FOR DE NOVO DESIGN OF PROTEINS WITH DIVERSE POCKETS
Descriptor:DENOVO NTF2, NITRATE ION
Authors:Bera, A.K., Basanta, B., Dimaio, F., Sankaran, B., Baker, D.
Deposit date:2020-03-09
Release date:2020-04-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A generative algorithm for de novo design of proteins with diverse pockets
To Be Published
6W40
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A GENERATIVE ALGORITHM FOR DE NOVO DESIGN OF PROTEINS WITH DIVERSE POCKETS
Descriptor:DENOVO NTF2
Authors:Bera, A.K., Basanta, B., Sankaran, B., Baker, D.
Deposit date:2020-03-09
Release date:2020-04-08
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:A generative algorithm for de novo design of proteins with diverse pockets
To Be Published
6O35
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED OCTAMERIC HELICAL-BUNDLE PROTEIN
Descriptor:de novo designed WSHC8
Authors:Bick, M.J., Xu, C., Sankaran, B., Baker, D.
Deposit date:2019-02-25
Release date:2020-03-18
Last modified:2020-04-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Computational Design of Transmembrane Channels
To Be Published
6N9H
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DE NOVO DESIGNED HOMO-TRIMERIC AMANTADINE-BINDING PROTEIN
Descriptor:amantadine-binding protein, (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, SODIUM ION
Authors:Park, J., Baker, D.
Deposit date:2018-12-03
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.039 Å)
Cite:De novo design of a homo-trimeric amantadine-binding protein.
Elife, 8, 2019