Author results

6S1U
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CRYSTAL STRUCTURE OF DIMERIC M-PMV PROTEASE C7A/D26N/C106A MUTANT IN COMPLEX WITH INHIBITOR
Descriptor:Gag-Pro-Pol polyprotein, PRO-0A1-VAL-PSA-ALA-MET-THR
Authors:Wosicki, S., Gilski, M., Jaskolski, M., Zabranska, H., Pichova, I.
Deposit date:2019-06-19
Release date:2019-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comparison of a retroviral protease in monomeric and dimeric states.
Acta Crystallogr D Struct Biol, 75, 2019
6S1V
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CRYSTAL STRUCTURE OF DIMERIC M-PMV PROTEASE D26N MUTANT IN COMPLEX WITH INHIBITOR
Descriptor:Gag-Pro-Pol polyprotein, PRO-0A1-VAL-PSA-ALA-MET-THR
Authors:Wosicki, S., Gilski, M., Jaskolski, M., Zabranska, H., Pichova, I.
Deposit date:2019-06-19
Release date:2019-10-16
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Comparison of a retroviral protease in monomeric and dimeric states.
Acta Crystallogr D Struct Biol, 75, 2019
6S1W
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CRYSTAL STRUCTURE OF DIMERIC M-PMV PROTEASE D26N MUTANT
Descriptor:Gag-Pro-Pol polyprotein
Authors:Wosicki, S., Gilski, M., Jaskolski, M., Zabranska, H., Pichova, I.
Deposit date:2019-06-19
Release date:2019-10-16
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Comparison of a retroviral protease in monomeric and dimeric states.
Acta Crystallogr D Struct Biol, 75, 2019
6P6F
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BG505 SOSIP-I53-50NP
Descriptor:I53-50A.1NT1, I53-50B.4PT1
Authors:Berndsen, Z.T., Ward, A.B.
Deposit date:2019-06-03
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle.
Nat Commun, 10, 2019
6NUK
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DE NOVO DESIGNED PROTEIN FERREDOG-DIESEL
Descriptor:Ferredog-Diesel
Authors:Koepnick, B., Bick, M.J., DiMaio, F., Norgard-Solano, T., Baker, D.
Deposit date:2019-02-01
Release date:2019-06-12
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:De novo protein design by citizen scientists.
Nature, 570, 2019
6NE4
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DESIGNED REPEAT PROTEIN SPECIFICALLY IN COMPLEX WITH FZ7CRD
Descriptor:Designed repeat binding protein, Frizzled-7, SULFATE ION, ...
Authors:Miao, Y., Jude, K.M., Garcia, K.C.
Deposit date:2018-12-16
Release date:2019-05-15
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.648 Å)
Cite:Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
6NE1
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DESIGNED REPEAT PROTEIN IN COMPLEX WITH FZ4
Descriptor:Frizzled-4, Pfs, NACHT and Ankyrin domain protein, ...
Authors:Miao, Y., Jude, K.M., Garcia, K.C.
Deposit date:2018-12-15
Release date:2019-05-15
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (3.011 Å)
Cite:Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
6NE2
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DESIGNED REPEAT PROTEIN IN COMPLEX WITH FZ7
Descriptor:Designed repeat protein binder, Frizzled-7, ACETATE ION, ...
Authors:Miao, Y., Jude, K.M., Garcia, K.C.
Deposit date:2018-12-15
Release date:2019-05-15
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.299 Å)
Cite:Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
6NDZ
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DESIGNED REPEAT PROTEIN IN COMPLEX WITH FZ8
Descriptor:Frizzled-8, Designed repeat binding protein, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Miao, Y., Jude, K.M., Garcia, K.C.
Deposit date:2018-12-14
Release date:2019-05-15
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.264 Å)
Cite:Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
6Q4Q
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THE CRYSTAL STRUCTURE OF CK2A BOUND TO P2-C4
Descriptor:Casein kinase II subunit alpha, Stapled peptide, GLYCEROL, ...
Authors:Brear, P., Iegre, J., Baker, D., Tan, Y., Sore, H., Donovan, D., Spring, D., Chandra, V., Hyvonen, M.
Deposit date:2018-12-06
Release date:2019-04-24
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Efficient development of stable and highly functionalised peptides targeting the CK2 alpha /CK2 beta protein-protein interaction.
Chem Sci, 10, 2019
6NAF
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DE NOVO DESIGNED HOMO-TRIMERIC AMANTADINE-BINDING PROTEIN
Descriptor:amantadine-binding protein, (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, SODIUM ION
Authors:Selvaraj, B., Park, J., Cuneo, M.J., Myles, D.A.A., Baker, D.
Deposit date:2018-12-05
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.923 Å), NEUTRON DIFFRACTION
Cite:De novo design of a homo-trimeric amantadine-binding protein.
Elife, 8, 2019
6N9H
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DE NOVO DESIGNED HOMO-TRIMERIC AMANTADINE-BINDING PROTEIN
Descriptor:amantadine-binding protein, (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, SODIUM ION
Authors:Park, J., Baker, D.
Deposit date:2018-12-03
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.039 Å)
Cite:De novo design of a homo-trimeric amantadine-binding protein.
Elife, 8, 2019
6Q38
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THE CRYSTAL STRUCTURE OF CK2A BOUND TO P1-C4
Descriptor:Casein kinase II subunit alpha, Stapled Peptide, BENZOIC ACID
Authors:Brear, P., Iegre, J., Baker, D., Tan, Y., Sore, H., Donovan, D., Spring, D., Chandra, V., Hyvonen, M.
Deposit date:2018-12-03
Release date:2019-04-24
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Efficient development of stable and highly functionalised peptides targeting the CK2 alpha /CK2 beta protein-protein interaction.
Chem Sci, 10, 2019
6N4N
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CRYSTAL STRUCTURE OF THE DESIGNED PROTEIN DNCR2/DANOPREVIR/NS3A COMPLEX
Descriptor:NS3 protease, Rosetta-designed danoprevir/NS3a complex reader 2, ZINC ION, ...
Authors:Wang, Z., Foight, G.W., Baker, D., Maly, D.J.
Deposit date:2018-11-19
Release date:2019-09-11
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Multi-input chemical control of protein dimerization for programming graded cellular responses.
Nat.Biotechnol., 37, 2019
6MSP
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DE NOVO DESIGNED PROTEIN FOLDIT3
Descriptor:De novo Designed Protein Foldit3
Authors:Liu, G., Ishida, Y., Swapna, G.V.T., Kleinfelter, S., Koepnick, B., Baker, D., Montelione, G.T.
Deposit date:2018-10-17
Release date:2019-06-12
Last modified:2019-07-03
Method:SOLUTION NMR
Cite:De novo protein design by citizen scientists.
Nature, 570, 2019
6MSQ
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CRYSTAL STRUCTURE OF PRO-2.3
Descriptor:pRO-2.3
Authors:Boyken, S.E., Bick, M.J., Baker, D.
Deposit date:2018-10-17
Release date:2019-05-08
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:De novo design of tunable, pH-driven conformational changes.
Science, 364, 2019
6MSR
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CRYSTAL STRUCTURE OF PRO-2.5
Descriptor:pRO-2.5
Authors:Bick, M.J., Boyken, S.E., Baker, D.
Deposit date:2018-10-17
Release date:2019-05-08
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:De novo design of tunable, pH-driven conformational changes.
Science, 364, 2019
6MRR
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DE NOVO DESIGNED PROTEIN FOLDIT1
Descriptor:Foldit1
Authors:Koepnick, B., Bick, M.J., Estep, R.D., Kleinfelter, S., Wei, L., Baker, D.
Deposit date:2018-10-15
Release date:2019-06-12
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:De novo protein design by citizen scientists.
Nature, 570, 2019
6MRS
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DE NOVO DESIGNED PROTEIN PEAK6
Descriptor:Peak6, SULFATE ION
Authors:Koepnick, B., Boykov, A., Baker, D.
Deposit date:2018-10-15
Release date:2019-06-12
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.541 Å)
Cite:De novo protein design by citizen scientists.
Nature, 570, 2019
6MOE
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MONOMERIC DARPIN E2 COMPLEX WITH EPOR
Descriptor:E2 DARPin, Erythropoietin receptor, PHOSPHATE ION, ...
Authors:Jude, K.M., Mohan, K., Garcia, K.C.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOF
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MONOMERIC DARPIN G2 COMPLEX WITH EPOR
Descriptor:G2 DARPin, Erythropoietin receptor, 1,2-ETHANEDIOL
Authors:Jude, K.M., Mohan, K., Garcia, K.C.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.894 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOG
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DIMERIC DARPIN C_R3
Descriptor:DARPin C_R3, 1,2-ETHANEDIOL, TRIETHYLENE GLYCOL
Authors:Jude, K.M., Mohan, K., Garcia, K.C.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOH
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DIMERIC DARPIN C_R3 COMPLEX WITH EPOR
Descriptor:Dimeric DARPin E2C (C_R3), Erythropoietin receptor, PHOSPHATE ION, ...
Authors:Jude, K.M., Mohan, K., Garcia, K.C.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOI
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DIMERIC DARPIN C_ANGLE_R5 COMPLEX WITH EPOR
Descriptor:Dimeric DARPing CCR5 (C_angle_R5), Erythropoietin receptor, SULFATE ION, ...
Authors:Jude, K.M., Mohan, K., Garcia, K.C., Guo, Y.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.065 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOJ
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DIMERIC DARPIN A_ANGLE_R5 COMPLEX WITH EPOR
Descriptor:Dimeric DARPin ACR5 (A_angle_R5), Erythropoietin receptor, D(-)-TARTARIC ACID, ...
Authors:Jude, K.M., Mohan, K., Garcia, K.C.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.431 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019