Author results

1G7C
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YEAST EEF1A:EEF1BA IN COMPLEX WITH GDPNP
Descriptor:ELONGATION FACTOR 1-ALPHA, ELONGATION FACTOR 1-BETA, GUANOSINE-5'-MONOPHOSPHATE
Authors:Andersen, G.R., Valente, L., Pedersen, L., Kinzy, T.G., Nyborg, J.
Deposit date:2000-11-10
Release date:2000-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1IJE
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NUCLEOTIDE EXCHANGE INTERMEDIATES IN THE EEF1A-EEF1BA COMPLEX
Descriptor:elongation factor 1-alpha, elongation factor 1-beta, GUANOSINE-5'-DIPHOSPHATE
Authors:Andersen, G.R., Valente, L., Pedersen, L., Kinzy, T.G., Nyborg, J.
Deposit date:2001-04-26
Release date:2001-05-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1IJF
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NUCLEOTIDE EXCHANGE MECHANISMS IN THE EEF1A-EEF1BA COMPLEX
Descriptor:elongation factor 1-alpha, elongation factor 1-beta, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Andersen, G.R., Valente, L., Pedersen, L., Kinzy, T.G., Nyborg, J.
Deposit date:2001-04-26
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1D2E
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CRYSTAL STRUCTURE OF MITOCHONDRIAL EF-TU IN COMPLEX WITH GDP
Descriptor:ELONGATION FACTOR TU (EF-TU), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Andersen, G.R., Thirup, S., Spremulli, L.L., Nyborg, J.
Deposit date:1999-09-23
Release date:1999-09-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:High resolution crystal structure of bovine mitochondrial EF-Tu in complex with GDP.
J.Mol.Biol., 297, 2000
1F60
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CRYSTAL STRUCTURE OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
Descriptor:ELONGATION FACTOR EEF1A, ELONGATION FACTOR EEF1BA
Authors:Andersen, G.R., Pedersen, L., Valente, L., Kinzy, T.G., Nyborg, J.
Deposit date:2000-06-19
Release date:2000-07-04
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha.
Mol.Cell, 6, 2000
3EX7
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THE CRYSTAL STRUCTURE OF EJC IN ITS TRANSITION STATE
Descriptor:Protein mago nashi homolog, RNA-binding protein 8A, Eukaryotic initiation factor 4A-III, ...
Authors:Andersen, G.R., Nielsen, K.H.
Deposit date:2008-10-16
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Mechanism of ATP turnover inhibition in the EJC
Rna, 15, 2009
5I8K
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HHH1 FAB FRAGMENT
Descriptor:HHH1 Fab Light chain, HHH1 Fab Heavy chain
Authors:Andersen, G.R., Spillner, E.
Deposit date:2016-02-19
Release date:2016-03-23
Method:X-RAY DIFFRACTION (1.771 Å)
Cite:HHH1 Fab fragment
To be published
5I8O
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HMM5 FAB IN COMPLEX WITH DISACCHARIDE
Descriptor:HMM5 antibody heavy chain, HMM5 antibody light chain, ALPHA-L-FUCOSE, ...
Authors:Andersen, G.R., Tjerrild, L.M., Spillner, E.
Deposit date:2016-02-19
Release date:2016-03-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of HMM5 Fab with a bound disaccharide
To be published
4F4O
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STRUCTURE OF THE HAPTOGLOBIN-HAEMOGLOBIN COMPLEX
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, Haptoglobin, ...
Authors:Andersen, C.B.F., Torvund-Jensen, M., Nielsen, M.J., Oliveira, C.L.P., Hersleth, H.P., Andersen, N.H., Pedersen, J.S., Andersen, G.R., Moestrup, S.K.
Deposit date:2012-05-11
Release date:2012-08-29
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the haptoglobin-haemoglobin complex.
Nature, 489, 2012
2B7B
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YEAST GUANINE NUCLEOTIDE EXCHANGE FACTOR EEF1BALPHA K205A MUTANT IN COMPLEX WITH EEF1A AND GDP
Descriptor:Elongation factor 1-alpha, elongation factor-1 beta, GUANOSINE-5'-DIPHOSPHATE
Authors:Pittman, Y.R., Valente, L., Jeppesen, M.G., Andersen, G.R., Patel, S., Kinzy, T.G.
Deposit date:2005-10-04
Release date:2006-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha
J.Biol.Chem., 281, 2006
2B7C
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YEAST GUANINE NUCLEOTIDE EXCHANGE FACTOR EEF1BALPHA K205A MUTANT IN COMPLEX WITH EEF1A
Descriptor:Elongation factor 1-alpha, elongation factor-1 beta
Authors:Pittman, Y.R., Valente, L., Jeppesen, M.G., Andersen, G.R., Patel, S., Kinzy, T.G.
Deposit date:2005-10-04
Release date:2006-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha
J.Biol.Chem., 281, 2006
2HYI
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STRUCTURE OF THE HUMAN EXON JUNCTION COMPLEX WITH A TRAPPED DEAD-BOX HELICASE BOUND TO RNA
Descriptor:5'-R(*UP*UP*UP*UP*UP*U)-3', Protein mago nashi homolog, RNA-binding protein 8A, ...
Authors:Andersen, C.B.F., Le Hir, H., Andersen, G.R.
Deposit date:2006-08-06
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
Science, 313, 2006
2IW3
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ELONGATION FACTOR 3 IN COMPLEX WITH ADP
Descriptor:ELONGATION FACTOR 3A, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION
Authors:Andersen, C.B.F., Becker, T., Blau, M., Anand, M., Halic, M., Balar, B., Mielke, T., Boesen, T., Pedersen, J.S., Spahn, C.M.T., Kinzy, T.G., Andersen, G.R., Beckmann, R.
Deposit date:2006-06-26
Release date:2006-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site.
Nature, 443, 2006
2IWH
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STRUCTURE OF YEAST ELONGATION FACTOR 3 IN COMPLEX WITH ADPNP
Descriptor:ELONGATION FACTOR 3A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION
Authors:Andersen, C.B.F., Becker, T., Blau, M., Anand, M., Halic, M., Balar, B., Mielke, T., Boesen, T., Pedersen, J.S., Spahn, C.M.T., Kinzy, T.G., Andersen, G.R., Beckmann, R.
Deposit date:2006-06-30
Release date:2006-08-09
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site.
Nature, 443, 2006
2IX3
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STRUCTURE OF YEAST ELONGATION FACTOR 3
Descriptor:ELONGATION FACTOR 3, SULFATE ION
Authors:Andersen, C.B.F., Becker, T., Blau, M., Anand, M., Halic, M., Balar, B., Mielke, T., Boesen, T., Pedersen, J.S., Spahn, C.M.T., Kinzy, T.G., Andersen, G.R., Beckmann, R.
Deposit date:2006-07-06
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site.
Nature, 443, 2006
2IX8
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MODEL FOR EEF3 BOUND TO AN 80S RIBOSOME
Descriptor:ELONGATION FACTOR 3A
Authors:Andersen, C.B.F., Becker, T., Blau, M., Anand, M., Halic, M., Balar, B., Mielke, T., Boesen, T., Pedersen, J.S., Spahn, C.M.T., Kinzy, T.G., Andersen, G.R., Beckmann, R.
Deposit date:2006-07-07
Release date:2007-07-10
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site.
Nature, 443, 2006
3KQ4
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STRUCTURE OF INTRINSIC FACTOR-COBALAMIN BOUND TO ITS RECEPTOR CUBILIN
Descriptor:Gastric intrinsic factor, Cubilin, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Andersen, C.B.F., Madsen, M., Moestrup, S.K., Andersen, G.R.
Deposit date:2009-11-17
Release date:2010-03-09
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for receptor recognition of vitamin-B(12)-intrinsic factor complexes.
Nature, 464, 2010
3PRX
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STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH CVF AND SSL7
Descriptor:Complement C5, Cobra venom factor, Superantigen-like protein 7, ...
Authors:Laursen, N.S., Andersen, G.R., Sottrup-Jensen, L., Andersen, K.R., Spillner, E., Braren, I.
Deposit date:2010-11-30
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
3PVM
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STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH CVF
Descriptor:Complement C5, Cobra venom factor, N-ACETYL-D-GLUCOSAMINE
Authors:Laursen, N.S., Andersen, K.R., Braren, I., Sottrup-Jensen, L., Spillner, E., Andersen, G.R.
Deposit date:2010-12-07
Release date:2011-01-19
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
5NLU
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STRUCTURE OF NB36 CRYSTAL FORM 1
Descriptor:single domain llama antibody Nb36, SULFATE ION
Authors:Hansen, S.B., Andersen, K.R., Laursen, N.S., Andersen, G.R.
Deposit date:2017-04-05
Release date:2017-05-31
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.193 Å)
Cite:Introducing site-specific cysteines into nanobodies for mercury labelling allows de novo phasing of their crystal structures.
Acta Crystallogr D Struct Biol, 73, 2017
5NLW
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STRUCTURE OF NB36 CRYSTAL FORM 2
Descriptor:nanobody Nb36, SULFATE ION
Authors:Hansen, S.B., Andersen, K.R., Laursen, N.S., Andersen, G.R.
Deposit date:2017-04-05
Release date:2017-05-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Introducing site-specific cysteines into nanobodies for mercury labelling allows de novo phasing of their crystal structures.
Acta Crystallogr D Struct Biol, 73, 2017
5NM0
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NB36 SER85CYS WITH HG, CRYSTAL FORM 1
Descriptor:Nb36, MERCURY (II) ION
Authors:Hansen, S.B., Andersen, K.R., Laursen, N.S., Andersen, G.R.
Deposit date:2017-04-05
Release date:2017-06-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Introducing site-specific cysteines into nanobodies for mercury labelling allows de novo phasing of their crystal structures.
Acta Crystallogr D Struct Biol, 73, 2017
5NML
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NB36 SER85CYS WITH HG BOUND
Descriptor:Nanobody Nb36 Ser85Cys, MERCURY (II) ION, 1,2-ETHANEDIOL
Authors:Hansen, S.B., Andersen, K.R., Laursen, N.S., Andersen, G.R.
Deposit date:2017-04-06
Release date:2017-06-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Introducing site-specific cysteines into nanobodies for mercury labelling allows de novo phasing of their crystal structures.
Acta Crystallogr D Struct Biol, 73, 2017
6EHG
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COMPLEMENT COMPONENT C3B IN COMPLEX WITH A NANOBODY
Descriptor:Complement C3, hC3Nb1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Jensen, R.K., Andersen, K.R., Gadeberg, T.A.F., Laursen, N.S., Andersen, G.R.
Deposit date:2017-09-13
Release date:2018-02-14
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.
J. Biol. Chem., 293, 2018
1N0U
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CRYSTAL STRUCTURE OF YEAST ELONGATION FACTOR 2 IN COMPLEX WITH SORDARIN
Descriptor:Elongation factor 2, [1R-(1.ALPHA.,3A.BETA.,4.BETA.,4A.BETA.,7.BETA.,7A.ALPHA.,8A.BETA.)]8A-[(6-DEOXY-4-O-METHYL-BETA-D-ALTROPYRANOSYLOXY)METHYL]-4-FORMYL-4,4A,5,6,7,7A,8,8A-OCTAHYDRO-7-METHYL-3-(1-METHYLETHYL)-1,4-METHANO-S-INDACENE-3A(1H)-CARBOXYLIC ACID
Authors:Joergensen, R., Ortiz, P.A., Carr-Schmid, A., Nissen, P., Kinzy, T.G., Andersen, G.R.
Deposit date:2002-10-15
Release date:2003-02-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase.
Nat. Struct. Biol., 10, 2003