8R61

Structure of IgE delta epsilon 3-4 in complex with a kappa binding nanobody

Summary for 8R61

Entry DOI	10.2210/pdb8r61/pdb
Descriptor	Immunoglobulin E VH-Ceps1-Ceps1, HMM5 IgE light chain, kappa binding nanobody (3 entities in total)
Functional Keywords	adaptive immune system ige allergy, immune system
Biological source	Homo sapiens More
Total number of polymer chains	18
Total formula weight	442671.84
Authors	Andersen, G.R.,Gandini, R. (deposition date: 2023-11-20, release date: 2023-11-29, Last modification date: 2024-11-13)
Primary citation	Jensen, R.K.,Miehe, M.,Gandini, R.,Jorgensen, M.H.,Spillner, E.,Andersen, G.R. The dynamics of hinge flexibility in receptor bound immunoglobulin E revealed by electron microscopy Biorxiv, 2023 Cited by DOI: 10.1101/2023.02.17.528943 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation