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6IF2
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COMPLEX STRUCTURE OF RAB35 AND ITS EFFECTOR RUSC2
Descriptor:Ras-related protein Rab-35, Iporin, MAGNESIUM ION, ...
Authors:Lin, L., Zhu, J., Zhang, R.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
6IF3
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COMPLEX STRUCTURE OF RAB35 AND ITS EFFECTOR ACAP2
Descriptor:Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, Ras-related protein Rab-35, ...
Authors:Lin, L., Zhu, J., Zhang, R.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
6IYN
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SOLUTION STRUCTURE OF CAMELID NANOBODY NB26 AGAINST AFLATOXIN B1
Descriptor:Nb26
Authors:Nie, Y., He, T., Zhu, J., Li, S.L., Hu, R., Yang, Y.H.
Deposit date:2018-12-17
Release date:2019-01-23
Last modified:2019-04-10
Method:SOLUTION NMR
Cite:Chemical shift assignments of a camelid nanobody against aflatoxin B1.
Biomol NMR Assign, 13, 2019
6JIP
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE SP_0782 (RESIDUES 7-79) IN COMPLEX WITH SINGLE-STRANDED DNA DT6
Descriptor:SP_0782, DNA (5'-D(*TP*TP*TP*TP*T)-3'), PENTAETHYLENE GLYCOL
Authors:Fang, X., Lu, G., Li, S., Zhu, J., Yang, Y., Gong, P.
Deposit date:2019-02-22
Release date:2019-11-27
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (1.659 Å)
Cite:Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins.
Nucleic Acids Res., 48, 2020
6JIQ
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE SP_0782 (RESIDUES 7-79) IN COMPLEX WITH SINGLE-STRANDED DNA DT6
Descriptor:SP_0782, DNA (5'-D(*TP*TP*TP*TP*T)-3')
Authors:Fang, X., Lu, G., Li, S., Zhu, J., Yang, Y., Gong, P.
Deposit date:2019-02-22
Release date:2019-11-27
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins.
Nucleic Acids Res., 48, 2020
6K2I
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SOLUTION STRUCTURE OF CAMELID NANOBODY NB11 AGAINST AFLATOXIN B1
Descriptor:camelid nanobody Nb11
Authors:Nie, Y., Li, S.L., He, T., Zhu, J., Yang, Y.H.
Deposit date:2019-05-14
Release date:2019-06-05
Method:SOLUTION NMR
Cite:Solution structure of camelid nanobody Nb11 against aflatoxin B1
To Be Published
6L1W
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ZINC-FINGER ANTIVIRAL PROTEIN (ZAP) BOUND TO RNA
Descriptor:Zinc finger CCCH-type antiviral protein 1, RNA (5'-R(*CP*GP*UP*CP*GP*U)-3'), ZINC ION
Authors:Luo, X., Wang, X., Gao, Y., Zhu, J., Liu, S., Gao, G., Gao, P.
Deposit date:2019-09-30
Release date:2020-01-01
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein.
Cell Rep, 30, 2020
6UYD
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STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2MC3-V1 REDESIGNED CORE FROM GENOTYPE 1A BOUND TO BROADLY NEUTRALIZING ANTIBODY AR3C
Descriptor:Envelope glycoprotein E2, Fab AR3C heavy chain, Fab AR3C light chain, ...
Authors:Tzarum, N., Wilson, I.A., Zhu, J.
Deposit date:2019-11-13
Release date:2020-04-22
Last modified:2020-06-17
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6UYF
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STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2MC3-V1 REDESIGNED CORE FROM GENOTYPE 6A BOUND TO BROADLY NEUTRALIZING ANTIBODY AR3B
Descriptor:Fab AR3B heavy chain, Fab AR3B light chain, Envelope glycoprotein E2, ...
Authors:Tzarum, N., Wilson, I.A., Zhu, J.
Deposit date:2019-11-13
Release date:2020-04-22
Last modified:2020-06-17
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6UYG
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STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2C3 CORE FROM GENOTYPE 6A BOUND TO BROADLY NEUTRALIZING ANTIBODY AR3B AND NON NEUTRALIZING ANTIBODY E1
Descriptor:Envelope glycoprotein E2, Fab AR3A heavy chain, Fab AR3A light chain, ...
Authors:Tzarum, N., Wilson, I.A., Zhu, J.
Deposit date:2019-11-13
Release date:2020-04-22
Last modified:2020-06-17
Method:X-RAY DIFFRACTION (3.375 Å)
Cite:Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6UYM
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STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2MC3-V6 REDESIGNED CORE FROM GENOTYPE 1A BOUND TO BROADLY NEUTRALIZING ANTIBODY AR3C
Descriptor:Envelope glycoprotein E2, Fab AR3C heavy chain, Fab AR3C light chain, ...
Authors:Tzarum, N., Wilson, I.A., Zhu, J.
Deposit date:2019-11-13
Release date:2020-04-22
Last modified:2020-06-17
Method:X-RAY DIFFRACTION (2.848 Å)
Cite:Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6VYP
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CRYSTAL STRUCTURE OF THE LSD1/COREST HISTONE DEMETHYLASE BOUND TO ITS NUCLEOSOME SUBSTRATE
Descriptor:Histone H3, Histone H4, Histone H2A type 1, ...
Authors:Kim, S., Zhu, J., Eek, P., Yennawar, N., Song, T.
Deposit date:2020-02-27
Release date:2020-05-27
Last modified:2020-06-17
Method:X-RAY DIFFRACTION (4.99 Å)
Cite:Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate.
Mol.Cell, 78, 2020
3NIF
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THE CLOSED HEADPIECE OF INTEGRIN IIB 3 AND ITS COMPLEX WITH AN IIB 3 -SPECIFIC ANTAGONIST THAT DOES NOT INDUCE OPENING
Descriptor:Integrin alphaIIB beta3, Integrin beta-3, Monoclonal antibody 10E5 heavy chain, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2010-06-15
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening.
Blood, 116, 2010
3NIG
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THE CLOSED HEADPIECE OF INTEGRIN IIB 3 AND ITS COMPLEX WITH AN IIB 3 -SPECIFIC ANTAGONIST THAT DOES NOT INDUCE OPENING
Descriptor:Integrin alpha-IIb, Integrin beta-3, Monoclonal antibody 10E5 heavy chain, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2010-06-15
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening.
Blood, 116, 2010
3ZDX
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INTEGRIN ALPHAIIB BETA3 HEADPIECE AND RGD PEPTIDE COMPLEX
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, 10E5 FAB, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2012-12-03
Release date:2013-06-05
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZDY
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INTEGRIN ALPHAIIB BETA3 HEADPIECE AND RGD PEPTIDE COMPLEX
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, 10E5 FAB HEAVY CHAIN, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2012-12-03
Release date:2013-06-05
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZDZ
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INTEGRIN ALPHAIIB BETA3 HEADPIECE AND RGD PEPTIDE COMPLEX
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, 10E5 FAB HEAVY CHAIN, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2012-12-03
Release date:2013-06-05
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZE0
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INTEGRIN ALPHAIIB BETA3 HEADPIECE AND RGD PEPTIDE COMPLEX
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, 10E5 FAB HEAVY CHAIN, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2012-12-03
Release date:2013-06-05
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZE1
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INTEGRIN ALPHAIIB BETA3 HEADPIECE AND RGD PEPTIDE COMPLEX
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, 10E5 FAB HEAVY CHAIN, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2012-12-03
Release date:2013-06-05
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZE2
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INTEGRIN ALPHAIIB BETA3 HEADPIECE AND RGD PEPTIDE COMPLEX
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, 10E5 FAB HEAVY CHAIN, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2012-12-03
Release date:2013-06-05
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
5EIC
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN CREBBP IN COMPLEX WITH AYC
Descriptor:CREB-binding protein, 1,2-ETHANEDIOL, 2-[(chloroacetyl)amino]-5-[(E)-(4-sulfophenyl)diazenyl]benzenesulfonic acid
Authors:Dong, J., Caflisch, A.
Deposit date:2015-10-29
Release date:2016-11-16
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
5ENG
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN CREBBP IN COMPLEX WITH UP39
Descriptor:CREB-binding protein, methyl 2-[2-(3,5-dihydro-2~{H}-pyrazin-4-yl)ethoxy]-5-[(5-ethanoyl-2-ethoxy-phenyl)carbamoyl]benzoate
Authors:Dong, J., Caflisch, A.
Deposit date:2015-11-09
Release date:2016-11-23
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
5EP7
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN CREBBP IN COMPLEX WITH UN32
Descriptor:CREB-binding protein, 3-[(1-methyl-6-oxidanylidene-pyridin-3-yl)carbonylamino]benzoic acid
Authors:Dong, J., Caflisch, A.
Deposit date:2015-11-11
Release date:2016-11-23
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.198 Å)
Cite:Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
5H85
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN CREBBP IN COMPLEX WITH UO37D
Descriptor:CREB-binding protein, methyl 3-(7~{H}-purin-6-ylcarbamoyl)benzoate
Authors:Dong, J., Caflisch, A.
Deposit date:2015-12-23
Release date:2017-01-11
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
3RO2
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STRUCTURES OF THE LGN/NUMA COMPLEX
Descriptor:G-protein-signaling modulator 2, peptide of Nuclear mitotic apparatus protein 1, GLYCEROL
Authors:Shang, Y., Wei, Z.
Deposit date:2011-04-25
Release date:2012-03-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways
Mol.Cell, 43, 2011