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2YHX
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BU of 2yhx by Molmil
SEQUENCING A PROTEIN BY X-RAY CRYSTALLOGRAPHY. II. REFINEMENT OF YEAST HEXOKINASE B CO-ORDINATES AND SEQUENCE AT 2.1 ANGSTROMS RESOLUTION
Descriptor: 2-deoxy-2-{[(2-methylphenyl)carbonyl]amino}-alpha-D-glucopyranose, HEXOKINASE B
Authors:Steitz, T.A, Anderson, C.M, Stenkamp, R.E.
Deposit date:1978-03-20
Release date:1978-05-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Sequencing a protein by x-ray crystallography. II. Refinement of yeast hexokinase B co-ordinates and sequence at 2.1 A resolution.
J.Mol.Biol., 123, 1978
3HVT
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BU of 3hvt by Molmil
STRUCTURAL BASIS OF ASYMMETRY IN THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE HETERODIMER
Descriptor: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66)
Authors:Steitz, T.A, Smerdon, S.J, Jaeger, J, Wang, J, Kohlstaedt, L.A, Chirino, A.J, Friedman, J.M, Rice, P.A.
Deposit date:1994-07-25
Release date:1994-10-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
Proc.Natl.Acad.Sci.Usa, 91, 1994
2QA4
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BU of 2qa4 by Molmil
A more complete structure of the the L7/L12 stalk of the Haloarcula marismortui 50S large ribosomal subunit
Descriptor: 23S RIBOSOMAL RNA, 50S RIBOSOMAL PROTEIN L31E, 50S ribosomal protein L10e, ...
Authors:Steitz, T.A, Kavran, J.M.
Deposit date:2007-06-14
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the base of the L7/L12 stalk of the Haloarcula marismortui large ribosomal subunit: Analysis of L11 movements
J.Mol.Biol., 371, 2007
2ZIM
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BU of 2zim by Molmil
Pyrrolysyl-tRNA synthetase bound to adenylated pyrrolysine and pyrophosphate
Descriptor: (2R)-2-AMINO-6-({[(2S,3R)-3-METHYLPYRROLIDIN-2-YL]CARBONYL}AMINO)HEXANOYL [(2S,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL HYDROGEN (R)-PHOSPHATE, 1,2-ETHANEDIOL, PYROPHOSPHATE 2-, ...
Authors:Steitz, T.A, Kavran, J.M.
Deposit date:2008-02-19
Release date:2008-03-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3HIF
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BU of 3hif by Molmil
The crystal structure of apo wild type CAP at 3.6 A resolution.
Descriptor: Catabolite gene activator
Authors:Steitz, T.A, Sharma, H, Wang, J, Kong, J, Yu, S.
Deposit date:2009-05-19
Release date:2009-09-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Structure of apo-CAP reveals that large conformational changes are necessary for DNA binding.
Proc.Natl.Acad.Sci.USA, 106, 2009
1HKG
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BU of 1hkg by Molmil
STRUCTURAL DYNAMICS OF YEAST HEXOKINASE DURING CATALYSIS
Descriptor: HEXOKINASE A
Authors:Bennett Jr, W.S, Steitz, T.A.
Deposit date:1980-12-22
Release date:1981-02-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural dynamics of yeast hexokinase during catalysis.
Philos.Trans.R.Soc.London,Ser.B, 293, 1981
2ODR
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BU of 2odr by Molmil
Methanococcus Maripaludis Phosphoseryl-tRNA synthetase
Descriptor: phosphoseryl-tRNA synthetase
Authors:Steitz, T.A, Kamtekar, S.
Deposit date:2006-12-26
Release date:2007-02-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.228 Å)
Cite:Toward understanding phosphoseryl-tRNACys formation: the crystal structure of Methanococcus maripaludis phosphoseryl-tRNA synthetase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4V8A
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BU of 4v8a by Molmil
The structure of thermorubin in complex with the 70S ribosome from Thermus thermophilus.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Bulkley, D, Johnson, F.A, Steitz, T.A.
Deposit date:2011-12-05
Release date:2014-07-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge b2a of the ribosome.
J.Mol.Biol., 416, 2012
2REB
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BU of 2reb by Molmil
THE STRUCTURE OF THE E. COLI RECA PROTEIN MONOMER AND POLYMER
Descriptor: REC A
Authors:Story, R.M, Steitz, T.A.
Deposit date:1992-03-06
Release date:1993-10-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of the E. coli recA protein monomer and polymer.
Nature, 355, 1992
7JNH
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BU of 7jnh by Molmil
Crystal structure of a double-ENE RNA stability element in complex with a 28-mer poly(A) RNA
Descriptor: 28-mer poly(A) RNA, COBALT HEXAMMINE(III), Core double ENE RNA (Xtal construct) from Oryza sativa transposon,Core double ENE RNA (Xtal construct) from Oryza sativa transposon, ...
Authors:Torabi, S.F, Vaidya, A.T, Tycowski, K.T, DeGregorio, S.J, Wang, J, Shu, M.D, Steitz, T.A, Steitz, J.A.
Deposit date:2020-08-04
Release date:2021-01-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Science, 371, 2021
2RSL
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BU of 2rsl by Molmil
REFINEMENT OF GAMMA DELTA RESOLVASE REVEALS A STRIKINGLY FLEXIBLE MOLECULE
Descriptor: GAMMA DELTA-RESOLVASE, SULFATE ION
Authors:Rice, P.A, Steitz, T.A.
Deposit date:1993-09-08
Release date:1994-04-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Refinement of gamma delta resolvase reveals a strikingly flexible molecule.
Structure, 2, 1994
1KLN
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BU of 1kln by Molmil
DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7) MUTANT/DNA COMPLEX
Descriptor: DNA (5'-D(*GP*CP*CP*GP*CP*GP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*CP*GP*CP*GP*GP*CP*GP*GP*C)-3'), PROTEIN (DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7)), ...
Authors:Beese, L.S, Derbyshire, V, Steitz, T.A.
Deposit date:1994-05-24
Release date:1994-11-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of DNA polymerase I Klenow fragment bound to duplex DNA.
Science, 260, 1993
4PLX
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BU of 4plx by Molmil
Crystal structure of the triple-helical stability element at the 3' end of MALAT1
Descriptor: Core ENE hairpin and A-rich tract from MALAT1
Authors:Brown, J.A, Bulkley, D, Wang, J, Valenstein, M.L, Yario, T.A, Steitz, T.A, Steitz, J.A.
Deposit date:2014-05-19
Release date:2014-06-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix.
Nat.Struct.Mol.Biol., 21, 2014
1K73
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BU of 1k73 by Molmil
Co-crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit
Descriptor: 23S RRNA, 5S RRNA, ANISOMYCIN, ...
Authors:Hansen, J, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
Deposit date:2001-10-18
Release date:2003-07-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
J.Mol.Biol., 330, 2003
1TAQ
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BU of 1taq by Molmil
STRUCTURE OF TAQ DNA POLYMERASE
Descriptor: 2-O-octyl-beta-D-glucopyranose, TAQ DNA POLYMERASE, ZINC ION
Authors:Kim, Y, Eom, S.H, Wang, J, Lee, D.-S, Suh, S.W, Steitz, T.A.
Deposit date:1996-06-04
Release date:1996-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of Thermus aquaticus DNA polymerase.
Nature, 376, 1995
4M6F
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BU of 4m6f by Molmil
Dimer of the G-Segment Invertase bound to a DNA substrate
Descriptor: DNA-invertase, gix site analog
Authors:Ritacco, C.J, Wang, J, Steitz, T.A.
Deposit date:2013-08-09
Release date:2014-03-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.99 Å)
Cite:Exploiting large non-isomorphous differences for phase determination of a G-segment invertase-DNA complex.
Acta Crystallogr.,Sect.D, 70, 2014
1KFS
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BU of 1kfs by Molmil
DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7) MUTANT/DNA COMPLEX
Descriptor: DNA (5'-D(*GP*CP*TP*TP*AP*CP*G)-3'), MAGNESIUM ION, PROTEIN (DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7)), ...
Authors:Brautigam, C.A, Steitz, T.A.
Deposit date:1997-08-18
Release date:1998-02-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates.
J.Mol.Biol., 277, 1998
430D
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BU of 430d by Molmil
STRUCTURE OF SARCIN/RICIN LOOP FROM RAT 28S RRNA
Descriptor: MAGNESIUM ION, SARCIN/RICIN LOOP FROM RAT 28S R-RNA
Authors:Correll, C.C, Munishkin, A, Chan, Y.L, Ren, Z, Wool, I.G, Steitz, T.A.
Deposit date:1998-10-04
Release date:1998-10-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the ribosomal RNA domain essential for binding elongation factors.
Proc.Natl.Acad.Sci.USA, 95, 1998
4W2F
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BU of 4w2f by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with amicoumacin, mRNA and three deacylated tRNAs in the A, P and E sites
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
Deposit date:2014-09-12
Release date:2014-10-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4W2G
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BU of 4w2g by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (soaked), mRNA and three deacylated tRNAs in the A, P and E sites
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
Deposit date:2014-09-12
Release date:2014-10-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
5W2F
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BU of 5w2f by Molmil
Crystal Structure of the C-terminal Domain of Human eIF2D at 1.4 A resolution
Descriptor: Eukaryotic translation initiation factor 2D, FORMIC ACID
Authors:Vaidya, A.T, Lomakin, I.B, Joseph, N.N, Dmitriev, S.E, Steitz, T.A.
Deposit date:2017-06-06
Release date:2017-08-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of the C-terminal Domain of Human eIF2D and Its Implications on Eukaryotic Translation Initiation.
J. Mol. Biol., 429, 2017
2R6C
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BU of 2r6c by Molmil
Crystal Form BH2
Descriptor: DnaG Primase, Helicase Binding Domain, Replicative helicase
Authors:Bailey, S, Eliason, W.K, Steitz, T.A.
Deposit date:2007-09-05
Release date:2008-06-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of hexameric DnaB helicase and its complex with a domain of DnaG primase
Science, 318, 2007
4W2H
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BU of 4w2h by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (co-crystallized), mRNA and deacylated tRNA in the P site
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
Deposit date:2014-09-12
Release date:2014-10-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
3UJ3
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BU of 3uj3 by Molmil
Crystal Structure of the synaptic tetramer of the G-Segment Invertase (Gin)
Descriptor: DNA-invertase
Authors:Ritacco, C.J, Wang, J, Kamtekar, S, Steitz, T.A.
Deposit date:2011-11-07
Release date:2012-12-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Crystal structure of an intermediate of rotating dimers within the synaptic tetramer of the G-segment invertase.
Nucleic Acids Res., 41, 2013
3NCI
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BU of 3nci by Molmil
RB69 DNA Polymerase Ternary Complex with dCTP Opposite dG at 1.8 angstrom resolution
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Wang, M, Blaha, G, Steitz, T.A, Konigsberg, W.H, Wang, J.
Deposit date:2010-06-04
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Insights into base selectivity from the 1.8 A resolution structure of an RB69 DNA polymerase ternary complex.
Biochemistry, 50, 2011

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