4V5H | | E.COLI 70S RIBOSOME STALLED DURING TRANSLATION OF TNAC LEADER PEPTIDE. | | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Seidelt, B., Innis, C.A., Wilson, D.N., Gartmann, M., Armache, J., Villa, E., Trabuco, L.G., Becker, T., Mielke, T., Schulten, K., Steitz, T.A., Beckmann, R. | | Deposit date: | 2009-10-26 | | Release date: | 2014-07-09 | | Last modified: | 2018-04-18 | | Method: | ELECTRON MICROSCOPY (5.8 Å) | | Cite: | Structural insight into nascent polypeptide chain-mediated translational stalling.
Science, 326, 2009
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4V7W | | STRUCTURE OF THE THERMUS THERMOPHILUS RIBOSOME COMPLEXED WITH CHLORAMPHENICOL. | | Descriptor: | 16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ... | | Authors: | Bulkley, D.P., Innis, C.A., Blaha, G., Steitz, T.A. | | Deposit date: | 2010-08-16 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc.Natl.Acad.Sci.USA, 107, 2010
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4V7X | | STRUCTURE OF THE THERMUS THERMOPHILUS RIBOSOME COMPLEXED WITH ERYTHROMYCIN. | | Descriptor: | 16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ... | | Authors: | Bulkley, D.P., Innis, C.A., Blaha, G., Steitz, T.A. | | Deposit date: | 2010-08-17 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc.Natl.Acad.Sci.USA, 107, 2010
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4V7Y | | STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH AZITHROMYCIN. | | Descriptor: | 16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ... | | Authors: | Bulkley, D.P., Innis, C.A., Blaha, G., Steitz, T.A. | | Deposit date: | 2010-08-18 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc.Natl.Acad.Sci.USA, 107, 2010
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4V7Z | | STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH TELITHROMYCIN. | | Descriptor: | 16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ... | | Authors: | Bulkley, D.P., Innis, C.A., Blaha, G., Steitz, T.A. | | Deposit date: | 2010-08-18 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc.Natl.Acad.Sci.USA, 107, 2010
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4V8A | | THE STRUCTURE OF THERMORUBIN IN COMPLEX WITH THE 70S RIBOSOME FROM THERMUS THERMOPHILUS. | | Descriptor: | 23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Bulkley, D., Johnson, F.A., Steitz, T.A. | | Deposit date: | 2011-12-05 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge b2a of the ribosome.
J.Mol.Biol., 416, 2012
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4V8G | | CRYSTAL STRUCTURE OF RMF BOUND TO THE 70S RIBOSOME. | | Descriptor: | 16S Ribosomal RNA, 30S Ribosomal Protein S2, 30S Ribosomal Protein S3, ... | | Authors: | Polikanov, Y.S., Blaha, G.M., Steitz, T.A. | | Deposit date: | 2011-12-11 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.
Science, 336, 2012
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4V8H | | CRYSTAL STRUCTURE OF HPF BOUND TO THE 70S RIBOSOME. | | Descriptor: | 16S Ribosomal RNA, 30S Ribosomal Protein S2, 30S Ribosomal Protein S3, ... | | Authors: | Polikanov, Y.S., Blaha, G.M., Steitz, T.A. | | Deposit date: | 2011-12-11 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis.
Science, 336, 2012
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4V8I | | CRYSTAL STRUCTURE OF YFIA BOUND TO THE 70S RIBOSOME. | | Descriptor: | 16S Ribosomal RNA, 30S Ribosomal Protein S2, 30S Ribosomal Protein S3, ... | | Authors: | Polikanov, Y.S., Blaha, G.M., Steitz, T.A. | | Deposit date: | 2011-12-12 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.
Science, 336, 2012
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4V95 | | CRYSTAL STRUCTURE OF YAEJ BOUND TO THE 70S RIBOSOME | | Descriptor: | 16S Ribosomal RNA, 30S Ribosomal Protein S2, 30S Ribosomal Protein S3, ... | | Authors: | Gagnon, M.G., Seetharaman, S.V., Bulkley, D.P., Steitz, T.A. | | Deposit date: | 2012-01-27 | | Release date: | 2014-07-09 | | Last modified: | 2018-07-11 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome.
Science, 335, 2012
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4V9R | | CRYSTAL STRUCTURE OF ANTIBIOTIC DITYROMYCIN BOUND TO 70S RIBOSOME | | Descriptor: | 16S Ribosomal RNA, 30S Ribosomal Protein S2, 30S Ribosomal Protein S3, ... | | Authors: | Bulkley, D.P., Brandi, L., Polikanov, Y.S., Fabbretti, A., O'Connor, M., Gualerzi, C.O., Steitz, T.A. | | Deposit date: | 2013-12-05 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
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4V9S | | CRYSTAL STRUCTURE OF ANTIBIOTIC GE82832 BOUND TO 70S RIBOSOME | | Descriptor: | 16S Ribosomal RNA, 30S Ribosomal Protein S2, 30S Ribosomal Protein S3, ... | | Authors: | Bulkley, D.P., Brandi, L., Polikanov, Y.S., Fabbretti, A., O'Connor, M., Gualerzi, C.O., Steitz, T.A. | | Deposit date: | 2013-12-05 | | Release date: | 2014-07-09 | | Last modified: | 2018-06-27 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
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4W2E | | CRYSTAL STRUCTURE OF ELONGATION FACTOR 4 (EF4/LEPA) BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME | | Descriptor: | 23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Gagnon, M.G., Lin, J., Steitz, T.A. | | Deposit date: | 2014-06-04 | | Release date: | 2014-10-01 | | Last modified: | 2017-08-16 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome.
Science, 345, 2014
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4W2I | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH NEGAMYCIN, MRNA AND THREE DEACYLATED TRNAS IN THE A, P AND E SITES | | Descriptor: | 16S Ribosomal RNA, 30S Ribosomal Protein S2, 30S Ribosomal Protein S3, ... | | Authors: | Polikanov, Y.S., Szal, T., Jiang, F., Gupta, P., Matsuda, R., Shiozuka, M., Steitz, T.A., Vazquez-Laslop, N., Mankin, A.S. | | Deposit date: | 2014-09-12 | | Release date: | 2014-10-15 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Negamycin Interferes with Decoding and Translocation by Simultaneous Interaction with rRNA and tRNA.
Mol.Cell, 56, 2014
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4WPO | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH ELONGATION FACTOR G IN THE PRE-TRANSLOCATIONAL STATE | | Descriptor: | 23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L1, ... | | Authors: | Lin, J., Gagnon, M.G., Steitz, T.A. | | Deposit date: | 2014-10-20 | | Release date: | 2015-01-28 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
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4WQF | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH ELONGATION FACTOR G AND FUSIDIC ACID IN THE POST-TRANSLOCATIONAL STATE | | Descriptor: | 23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L1, ... | | Authors: | Lin, J., Gagnon, M.G., Steitz, T.A. | | Deposit date: | 2014-10-21 | | Release date: | 2015-01-28 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
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4WQU | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH ELONGATION FACTOR G TRAPPED BY THE ANTIBIOTIC DITYROMYCIN | | Descriptor: | 23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L1, ... | | Authors: | Lin, J., Gagnon, M.G., Steitz, T.A. | | Deposit date: | 2014-10-22 | | Release date: | 2015-01-28 | | Last modified: | 2016-05-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
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4WQY | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH ELONGATION FACTOR G IN THE POST-TRANSLOCATIONAL STATE (WITHOUT FUSITIC ACID) | | Descriptor: | 23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L1, ... | | Authors: | Lin, J., Gagnon, M.G., Steitz, T.A. | | Deposit date: | 2014-10-22 | | Release date: | 2015-01-28 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
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4Y4O | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME WITH RRNA MODIFICATIONS AND BOUND TO PROTEIN Y (YFIA) AT 2.3A RESOLUTION | | Descriptor: | 23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Polikanov, Y.S., Melnikov, S.V., Soll, D., Steitz, T.A. | | Deposit date: | 2015-02-10 | | Release date: | 2015-03-18 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol., 22, 2015
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4Y4P | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME WITH RRNA MODIFICATIONS AND BOUND TO MRNA AND A-, P- AND E-SITE TRNAS AT 2.5A RESOLUTION | | Descriptor: | 23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Polikanov, Y.S., Melnikov, S.V., Soll, D., Steitz, T.A. | | Deposit date: | 2015-02-10 | | Release date: | 2015-03-18 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol., 22, 2015
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4YLN | | E. COLI TRANSCRIPTION INITIATION COMPLEX - 17-BP SPACER AND 4-NT RNA | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zuo, Y., Steitz, T.A. | | Deposit date: | 2015-03-05 | | Release date: | 2015-04-22 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (5.5 Å) | | Cite: | Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble.
Mol.Cell, 58, 2015
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4YLO | | E. COLI TRANSCRIPTION INITIATION COMPLEX - 16-BP SPACER AND 4-NT RNA | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zuo, Y., Steitz, T.A. | | Deposit date: | 2015-03-05 | | Release date: | 2015-04-22 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (6 Å) | | Cite: | Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble.
Mol.Cell, 58, 2015
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4YLP | | E. COLI TRANSCRIPTION INITIATION COMPLEX - 16-BP SPACER AND 5-NT RNA | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zuo, Y., Steitz, T.A. | | Deposit date: | 2015-03-05 | | Release date: | 2015-04-22 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (5.5 Å) | | Cite: | Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble.
Mol.Cell, 58, 2015
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4Z3S | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH ANTIBIOTIC A201A, MRNA AND THREE TRNAS IN THE A, P AND E SITES AT 2.65A RESOLUTION | | Descriptor: | 23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Polikanov, Y.S., Starosta, A.L., Juette, M.F., Altman, R.B., Terry, D.S., Lu, W., Burnett, B.J., Dinos, G., Reynolds, K., Blanchard, S.C., Steitz, T.A., Wilson, D.N. | | Deposit date: | 2015-03-31 | | Release date: | 2015-06-03 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
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4Z8C | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME BOUND TO TRANSLATION INHIBITOR ONCOCIN | | Descriptor: | 23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Roy, R.N., Lomakin, I.B., Gagnon, M.G., Steitz, T.A. | | Deposit date: | 2015-04-08 | | Release date: | 2015-05-20 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin.
Nat.Struct.Mol.Biol., 22, 2015
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