Author results

4J9T
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CRYSTAL STRUCTURE OF A PUTATIVE, DE NOVO DESIGNED UNNATURAL AMINO ACID DEPENDENT METALLOPROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR61
Descriptor:designed unnatural amino acid dependent metalloprotein, GLYCEROL, ARSENIC
Authors:Forouhar, F., Lew, S., Seetharaman, J., Mills, J.H., Khare, S.D., Everett, J.K., Baker, D., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-02-17
Release date:2013-03-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Computational design of an unnatural amino Acid dependent metalloprotein with atomic level accuracy.
J.Am.Chem.Soc., 135, 2013
4JCA
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CRYSTAL STRUCTURE OF THE APO FORM OF THE EVOLVED VARIANT OF THE COMPUTATIONALLY DESIGNED SERINE HYDROLASE, OSH55.4_H1. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR273
Descriptor:serine hydrolase, RUBIDIUM ION, CITRIC ACID
Authors:Kuzin, A.P., Lew, S., Rajagopalan, S., Seetharaman, J., Tong, S., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-02-21
Release date:2013-03-20
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (2.411 Å)
Cite:Design of activated serine-containing catalytic triads with atomic-level accuracy.
Nat.Chem.Biol., 10, 2014
4JLL
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CRYSTAL STRUCTURE OF THE EVOLVED VARIANT OF THE COMPUTATIONALLY DESIGNED SERINE HYDROLASE, OSH55.4_H1 COVALENTLY BOUND WITH FP-ALKYNE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR273
Descriptor:Evolved variant of computationally designed serine hydrolase OSH55.4_H1, ethyl (R)-{10-[(hept-6-yn-1-ylcarbamoyl)oxy]decyl}phosphonofluoridate, CHLORIDE ION, ...
Authors:Kuzin, A., Lew, S., Rajagopalan, S., Seetharaman, J., Tong, S., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-03-12
Release date:2013-04-10
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Design of activated serine-containing catalytic triads with atomic-level accuracy.
Nat.Chem.Biol., 10, 2014
4JVV
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CRYSTAL STRUCTURE OF THE EVOLVED VARIANT OF THE COMPUTATIONALLY DESIGNED SERINE HYDROLASE, OSH55.4_H1, COVALENTLY BOUND WITH DIISOPROPYL FLUOROPHOSPHATE (DFP), NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR273
Descriptor:evolved variant of the computationally designed serine hydrolase
Authors:Kuzin, A., Lew, S., Rajagopalan, S., Seetharaman, J., Tong, S., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-03-26
Release date:2013-04-24
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2.288 Å)
Cite:Design of activated serine-containing catalytic triads with atomic-level accuracy.
Nat.Chem.Biol., 10, 2014
4LNY
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR422
Descriptor:Engineered Protein OR422, CADMIUM ION, CHLORIDE ION
Authors:Vorobiev, S., Su, M., Bjelic, S., Kipnis, Y., Wang, L., Sahdev, S., Xiao, R., Maglaqui, M., Kogan, S., Baker, D., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-07-12
Release date:2013-08-07
Method:X-RAY DIFFRACTION (1.929 Å)
Cite:Crystal Structure of Engineered Protein OR422.
To be Published
4LT9
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR404
Descriptor:Engineered Protein OR404
Authors:Vorobiev, S., Su, M., Bjelic, S., Kipnis, Y., Wang, L., Sahdev, S., Xiao, R., Kogan, S., Maglaqui, M., Baker, D., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-07-23
Release date:2013-08-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Engineered Protein OR404.
To be Published
4NE7
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CRYSTAL STRUCTURE OF ENGINEERED KUMAMOLISIN-AS FROM ALICYCLOBACILLUS SENDAIENSIS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR367
Descriptor:Kumamolisin-As, ZINC ION
Authors:Guan, R., Pultz, I.S., Siegel, J.B., Seetharaman, J., Kornhaber, G., Maglaqui, M., Mao, L., Xiao, R., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-10-28
Release date:2013-11-20
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Northeast Structural Genomics Consortium Target OR367
To be Published
4NEY
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CRYSTAL STRUCTURE OF AN ENGINEERED PROTEIN WITH FERREDOXIN FOLD, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR277
Descriptor:Engineered protein OR277, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, tetrabutylphosphonium
Authors:Guan, R., Lin, Y.-R., Koga, N., Koga, R., Castellanos, J., Seetharaman, J., Maglaqui, M., Sahdev, S., Mao, L., Xiao, R., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-10-30
Release date:2014-01-15
Method:X-RAY DIFFRACTION (2.323 Å)
Cite:Northeast Structural Genomics Consortium Target OR277
To be published
4NEZ
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CRYSTAL STRUCTURE OF AN ENGINEERED PROTEIN WITH FERREDOXIN FOLD, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR276
Descriptor:Engineered protein OR276, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, tetrabutylphosphonium
Authors:Guan, R., Lin, Y.-R., Koga, N., Koga, R., Castellanos, J., Seetharaman, J., Maglaqui, M., Sahdev, S., Mao, L., Xiao, R., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-10-30
Release date:2014-01-15
Method:X-RAY DIFFRACTION (2.395 Å)
Cite:Northeast Structural Genomics Consortium Target OR276
To be published
4NWN
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE T32-28
Descriptor:Uncharacterized protein, Propanediol utilization: polyhedral bodies pduT
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4NWO
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE T33-15
Descriptor:Molybdenum cofactor biosynthesis protein MogA, Chorismate mutase AroH, CALCIUM ION
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4NWP
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE, T33-21, CRYSTALLIZED IN SPACE GROUP R32
Descriptor:Putative uncharacterized protein, Uncharacterized protein, SULFATE ION, ...
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4NWQ
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE, T33-21, CRYSTALLIZED IN SPACE GROUP F4132
Descriptor:Putative uncharacterized protein PH0671, Uncharacterized protein, SULFATE ION
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4NWR
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE T33-28
Descriptor:integron gene cassette protein, Macrophage migration inhibitory factor-like protein
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4PQ8
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR465
Descriptor:DESIGNED PROTEIN OR465, CHLORIDE ION
Authors:Vorobiev, S., Parmeggiani, F., Seetharaman, J., Janjua, H., Xiao, R., Maglaqui, M., Park, K., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-02-28
Release date:2014-03-12
Method:X-RAY DIFFRACTION (1.833 Å)
Cite:Crystal Structure of Engineered Protein OR465.
To be Published
4PSJ
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR464.
Descriptor:OR464
Authors:Vorobiev, S., Parmeggiani, F., Seetharaman, J., Huang, P.-S., Janjua, H., Xiao, R., Maglaqui, M., Park, K., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-03-07
Release date:2014-03-26
Method:X-RAY DIFFRACTION (1.992 Å)
Cite:Crystal Structure of Engineered Protein OR464.
To be Published
4PWW
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR494.
Descriptor:OR494, PHOSPHATE ION, ACETIC ACID
Authors:Vorobiev, S., Lin, Y.-R., Seetharaman, J., Xiao, R., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-03-21
Release date:2014-04-09
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.471 Å)
Cite:Crystal Structure of Engineered Protein OR494.
To be Published
4QPZ
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CRYSTAL STRUCTURE OF THE FORMOLASE FLS_V2 IN SPACE GROUP P 21
Descriptor:Formolase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
Authors:Shen, B.W., Siegel, J.B., Stoddard, B.L., Baker, D.
Deposit date:2014-06-25
Release date:2015-03-11
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Computational protein design enables a novel one-carbon assimilation pathway.
Proc.Natl.Acad.Sci.USA, 112, 2015
4R80
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED BETA SHEET PROTEIN, CYSTATIN FOLD, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR486
Descriptor:OR486
Authors:Guan, R., Marcos, E., O'Connell, P., Seetharaman, J., Janjua, H., Xiao, R., Maglaqui, M., Acton, T.B., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-08-29
Release date:2014-09-24
Method:X-RAY DIFFRACTION (2.445 Å)
Cite:Crystal Structure of an engineered protein with denovo beta sheet design, Northeast Structural Genomics Consortium (NESG) Target OR486
To be Published
4RJV
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED FERREDOXIN FOLD, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR461
Descriptor:OR461
Authors:O'Connell, P.T., Lin, Y.-R., Guan, R., Koga, N., Koga, R., Seetharaman, J., Janjua, H., Xiao, R., Maglaqui, M., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-10-09
Release date:2014-10-22
Method:X-RAY DIFFRACTION (1.523 Å)
Cite:Northeast Structural Genomics Consortium Target OR461
To be published
4RV1
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR497.
Descriptor:Engineered Protein OR497, ACETATE ION
Authors:Vorobiev, S., Parmeggiani, F., Seetharaman, J., Xiao, R., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-11-24
Release date:2014-12-10
Method:X-RAY DIFFRACTION (2.573 Å)
Cite:Crystal Structure of Engineered Protein OR497.
To be Published
4RZP
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR366.
Descriptor:Engineered Protein OR366
Authors:Vorobiev, S., Parmeggiani, F., Dimaio, F., Seetharaman, J., Sahdev, S., Xiao, R., Kogan, S., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-12-23
Release date:2015-01-07
Last modified:2015-03-04
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Crystal Structure of Engineered Protein OR366
To be Published
4S02
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BIPHENYLALANINE MODIFIED THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI: I11BIF, F42W, Y79A, AND F123Y MUTANT
Descriptor:Threonine--tRNA ligase, DI(HYDROXYETHYL)ETHER
Authors:Pearson, A.D., Mills, J.H., Song, Y., Nasertorabi, F., Han, G.W., Baker, D., Stevens, R.C., Schultz, P.G.
Deposit date:2014-12-30
Release date:2015-03-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Transition states. Trapping a transition state in a computationally designed protein bottle.
Science, 347, 2015
4S03
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BIPHENYLALANINE MODIFIED THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI: I11BIF, Y79I, AND F123A MUTANT
Descriptor:Threonine--tRNA ligase
Authors:Pearson, A.D., Mills, J.H., Song, Y., Nasertorabi, F., Han, G.W., Baker, D., Stevens, R.C., Schultz, P.G.
Deposit date:2014-12-30
Release date:2015-03-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Transition states. Trapping a transition state in a computationally designed protein bottle.
Science, 347, 2015
4S0I
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BIPHENYLALANINE MODIFIED THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI: 11BIF, 42F, 79S, AND 123A MUTANT
Descriptor:Threonine--tRNA ligase
Authors:Pearson, A.D., Mills, J.H., Song, Y., Nasertorabi, F., Han, G.W., Baker, D., Stevens, R.C., Schultz, P.G.
Deposit date:2014-12-31
Release date:2015-03-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Transition states. Trapping a transition state in a computationally designed protein bottle.
Science, 347, 2015