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4WBP
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CRYSTAL STRUCTURE OF THE HR-1 DOMAIN OF HUMAN CAPRIN-1 IN THE P3121 SPACE GROUP
Descriptor:Caprin-1
Authors:Wu, Y., Zhu, J., Huang, X., Du, Z.
Deposit date:2014-09-03
Release date:2015-10-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the HR-1 domain of human caprin-1 in the P3121 space group
To be published
4Z7N
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INTEGRIN ALPHAIIBBETA3 IN COMPLEX WITH AGDV PEPTIDE
Descriptor:Integrin alpha-IIb, Integrin beta-3, Monoclonal antibody 10E5 heavy chain, ...
Authors:Lin, F.-Y., Zhu, J., Springer, T.A.
Deposit date:2015-04-07
Release date:2015-12-16
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.599 Å)
Cite:beta-Subunit Binding Is Sufficient for Ligands to Open the Integrin alpha IIb beta 3 Headpiece.
J.Biol.Chem., 291, 2016
4Z7O
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INTEGRIN ALPHAIIBBETA3 IN COMPLEX WITH AGDV PEPTIDE
Descriptor:Integrin alpha-IIb, Integrin beta-3, Monoclonal antibody 10E5 Fab heavy chain, ...
Authors:Lin, F.Y., Zhu, J., Springer, T.A.
Deposit date:2015-04-07
Release date:2016-01-27
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:beta-Subunit Binding Is Sufficient for Ligands to Open the Integrin alpha IIb beta 3 Headpiece.
J.Biol.Chem., 291, 2016
4Z7Q
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INTEGRIN ALPHAIIBBETA3 IN COMPLEX WITH AGDV-NH2 PEPTIDE
Descriptor:Integrin alpha-IIb, Integrin beta-3, Monoclonal antibody 10E5 heavy chain, ...
Authors:Lin, F.-Y., Zhu, J., Springer, T.A.
Deposit date:2015-04-07
Release date:2015-12-16
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:beta-Subunit Binding Is Sufficient for Ligands to Open the Integrin alpha IIb beta 3 Headpiece.
J.Biol.Chem., 291, 2016
5C14
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CRYSTAL STRUCTURE OF PECAM-1 D1D2 DOMAIN
Descriptor:Platelet endothelial cell adhesion molecule, GLYCEROL, COPPER (II) ION, ...
Authors:Zhou, D., Paddock, C., Newman, P., Zhu, J.
Deposit date:2015-06-12
Release date:2016-01-06
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for PECAM-1 homophilic binding.
Blood, 127, 2016
5J97
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DIMERIZATION DOMAIN OF CYTOPLASMIC ACTIVATION/PROLIFERATION-ASSOCIATED PROTEIN-2 (CAPRIN-2)
Descriptor:Caprin-2
Authors:Wu, Y., Zhu, J., Huang, X., Du, Z.
Deposit date:2016-04-08
Release date:2017-08-09
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Dimerization domain of cytoplasmic activation/proliferation-associated protein-2 (caprin-2)
To Be Published
5L6O
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EPHB3 KINASE DOMAIN COVALENTLY BOUND TO AN IRREVERSIBLE INHIBITOR (COMPOUND 3)
Descriptor:Ephrin type-B receptor 3, 1-(4-phenylazanylquinazolin-7-yl)ethanone, 1,4-DIETHYLENE DIOXIDE
Authors:Schimpl, M., Overman, R., Kung, A., Chen, Y.-C., Ni, F., Zhu, J., Turner, M., Molina, H., Zhang, C.
Deposit date:2016-05-30
Release date:2016-08-10
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Development of Specific, Irreversible Inhibitors for a Receptor Tyrosine Kinase EphB3.
J.Am.Chem.Soc., 138, 2016
5L6P
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EPHB3 KINASE DOMAIN COVALENTLY BOUND TO AN IRREVERSIBLE INHIBITOR (COMPOUND 6)
Descriptor:Ephrin type-B receptor 3, ~{N}-(4-phenylazanylquinazolin-7-yl)ethanamide, 1,4-DIETHYLENE DIOXIDE
Authors:Schimpl, M., Overman, R., Kung, A., Chen, Y.-C., Ni, F., Zhu, J., Turner, M., Molina, H., Zhang, C.
Deposit date:2016-05-30
Release date:2016-08-10
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Development of Specific, Irreversible Inhibitors for a Receptor Tyrosine Kinase EphB3.
J.Am.Chem.Soc., 138, 2016
5ZKL
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE SP_0782 (RESIDUES 7-79) IN COMPLEX WITH SINGLE-STRANDED DNA DT12
Descriptor:SP_0782, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3')
Authors:Lu, G., Li, S., Zhu, J., Yang, Y., Gong, P.
Deposit date:2018-03-24
Release date:2019-03-27
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA dT12
To be published
5ZKM
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE SP_0782 (RESIDUES 7-79) IN COMPLEX WITH SINGLE-STRANDED DNA TCTTCC
Descriptor:SP_0782, DNA (5'-D(P*TP*CP*TP*TP*CP*C)-3')
Authors:Lu, G., Li, S., Zhu, J., Yang, Y., Gong, P.
Deposit date:2018-03-24
Release date:2019-03-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA TCTTCC
To be published
6BXB
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CRYSTAL STRUCTURE OF AN EXTENDED B3 INTEGRIN P33
Descriptor:Chimera protein of Integrin beta-3 and Integrin alpha-L, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zhou, D., Zhu, J.
Deposit date:2017-12-18
Release date:2018-08-01
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure of an extended beta3integrin.
Blood, 132, 2018
6BXF
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CRYSTAL STRUCTURE OF AN EXTENDED B3 INTEGRIN L33
Descriptor:Chimera protein of Integrin beta-3 and Integrin alpha-L, GLYCEROL, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zhou, D., Zhu, J.
Deposit date:2017-12-18
Release date:2018-08-01
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of an extended beta3integrin.
Blood, 132, 2018
6BXJ
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STRUCTURE OF A SINGLE-CHAIN BETA3 INTEGRIN
Descriptor:Chimera protein of Integrin beta-3 and Integrin alpha-L, MAGNESIUM ION, N-ACETYL-D-GLUCOSAMINE
Authors:Thinn, A.M.M., Wang, Z., Zhou, D., Zhao, Y., Curtis, B.R., Zhu, J.
Deposit date:2017-12-18
Release date:2018-10-03
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.092 Å)
Cite:Autonomous conformational regulation of beta3integrin and the conformation-dependent property of HPA-1a alloantibodies.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C45
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CRYSTAL STRUCTURE OF HUMAN INORGANIC PYROPHOSPHATASE IN THE P212121 SPACE GROUP
Descriptor:Inorganic pyrophosphatase
Authors:Niu, H., Zhu, J., Huang, X., Du, Z.
Deposit date:2018-01-11
Release date:2019-01-16
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.388 Å)
Cite:Expression, purification and crystallization of the human protein PPA1
To be Published
6CKB
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CRYSTAL STRUCTURE OF AN EXTENDED BETA3 INTEGRIN P33
Descriptor:Chimera protein of Integrin beta-3 and Integrin alpha-L, MAGNESIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zhou, D., Zhu, J.
Deposit date:2018-02-27
Release date:2018-08-01
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of an extended beta3integrin.
Blood, 132, 2018
6IF2
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COMPLEX STRUCTURE OF RAB35 AND ITS EFFECTOR RUSC2
Descriptor:Ras-related protein Rab-35, Iporin, MAGNESIUM ION, ...
Authors:Lin, L., Zhu, J., Zhang, R.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
6IF3
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COMPLEX STRUCTURE OF RAB35 AND ITS EFFECTOR ACAP2
Descriptor:Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, Ras-related protein Rab-35, ...
Authors:Lin, L., Zhu, J., Zhang, R.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
6IYN
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SOLUTION STRUCTURE OF CAMELID NANOBODY NB26 AGAINST AFLATOXIN B1
Descriptor:Nb26
Authors:Nie, Y., He, T., Zhu, J., Li, S.L., Hu, R., Yang, Y.H.
Deposit date:2018-12-17
Release date:2019-01-23
Last modified:2019-04-10
Method:SOLUTION NMR
Cite:Chemical shift assignments of a camelid nanobody against aflatoxin B1.
Biomol NMR Assign, 13, 2019
6K2I
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SOLUTION STRUCTURE OF CAMELID NANOBODY NB11 AGAINST AFLATOXIN B1
Descriptor:camelid nanobody Nb11
Authors:Nie, Y., Li, S.L., He, T., Zhu, J., Yang, Y.H.
Deposit date:2019-05-14
Release date:2019-06-05
Method:SOLUTION NMR
Cite:Solution structure of camelid nanobody Nb11 against aflatoxin B1
To Be Published
3NIF
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THE CLOSED HEADPIECE OF INTEGRIN IIB 3 AND ITS COMPLEX WITH AN IIB 3 -SPECIFIC ANTAGONIST THAT DOES NOT INDUCE OPENING
Descriptor:Integrin alphaIIB beta3, Integrin beta-3, Monoclonal antibody 10E5 heavy chain, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2010-06-15
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening.
Blood, 116, 2010
3NIG
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THE CLOSED HEADPIECE OF INTEGRIN IIB 3 AND ITS COMPLEX WITH AN IIB 3 -SPECIFIC ANTAGONIST THAT DOES NOT INDUCE OPENING
Descriptor:Integrin alpha-IIb, Integrin beta-3, Monoclonal antibody 10E5 heavy chain, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2010-06-15
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening.
Blood, 116, 2010
3ZDX
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INTEGRIN ALPHAIIB BETA3 HEADPIECE AND RGD PEPTIDE COMPLEX
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, 10E5 FAB, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2012-12-03
Release date:2013-06-05
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZDY
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INTEGRIN ALPHAIIB BETA3 HEADPIECE AND RGD PEPTIDE COMPLEX
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, 10E5 FAB HEAVY CHAIN, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2012-12-03
Release date:2013-06-05
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZDZ
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INTEGRIN ALPHAIIB BETA3 HEADPIECE AND RGD PEPTIDE COMPLEX
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, 10E5 FAB HEAVY CHAIN, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2012-12-03
Release date:2013-06-05
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZE0
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INTEGRIN ALPHAIIB BETA3 HEADPIECE AND RGD PEPTIDE COMPLEX
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, 10E5 FAB HEAVY CHAIN, ...
Authors:Zhu, J.H., Zhu, J.Q., Springer, T.A.
Deposit date:2012-12-03
Release date:2013-06-05
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013