Author results

2RI7
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CRYSTAL STRUCTURE OF PHD FINGER-LINKER-BROMODOMAIN Y17E MUTANT FROM HUMAN BPTF IN THE H3(1-9)K4ME2 BOUND STATE
分子名称:Nucleosome-remodeling factor subunit BPTF, histone H3.1, ZINC ION, ...
著者Li, H., Patel, D.J.
登録日2007-10-10
公開日2007-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2TOB
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SOLUTION STRUCTURE OF THE TOBRAMYCIN-RNA APTAMER COMPLEX, NMR, 13 STRUCTURES
分子名称:RNA (5'-R(*AP*CP*UP*UP*GP*GP*UP*UP*UP*AP*GP*GP*UP*AP*AP*UP*GP*AP*GP*U)-3'), 3-DEOXY-3-AMINO GLUCOSE, 2,3,6-TRIDEOXY-2,6-DIAMINO GLUCOSE, ...
著者Jiang, L., Patel, D.J.
登録日1998-06-17
公開日1999-06-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the tobramycin-RNA aptamer complex.
Nat.Struct.Biol., 5, 1998
3CZ3
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CRYSTAL STRUCTURE OF TOMATO ASPERMY VIRUS 2B IN COMPLEX WITH SIRNA
分子名称:RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*A)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*G)-3'), Protein 2b
著者Ma, J.B., Li, F., Ding, S.W., Patel, D.J.
登録日2008-04-27
公開日2009-05-05
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献Structural Basis for siRNA Recognition by 2b, a Viral Suppressor of Non-Cell Autonomous RNA Silencing
To be Published
3D1B
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TETRAGONAL CRYSTAL STRUCTURE OF TAS3 C-TERMINAL ALPHA MOTIF
分子名称:RNA-induced transcriptional silencing complex protein tas3
著者Li, H., Patel, D.J.
登録日2008-05-05
公開日2009-04-21
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
3D1D
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HEXAGONAL CRYSTAL STRUCTURE OF TAS3 C-TERMINAL ALPHA MOTIF
分子名称:RNA-induced transcriptional silencing complex protein tas3
著者Li, H., Patel, D.J.
登録日2008-05-05
公開日2009-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
3D2N
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CRYSTAL STRUCTURE OF MBNL1 TANDEM ZINC FINGER 1 AND 2 DOMAIN
分子名称:Muscleblind-like protein 1, ZINC ION
著者Teplova, M., Patel, D.J.
登録日2008-05-08
公開日2008-12-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1.
Nat.Struct.Mol.Biol., 15, 2008
3D2Q
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CRYSTAL STRUCTURE OF MBNL1 TANDEM ZINC FINGER 3 AND 4 DOMAIN
分子名称:Muscleblind-like protein 1, ZINC ION
著者Teplova, M., Patel, D.J.
登録日2008-05-08
公開日2008-12-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1.
Nat.Struct.Mol.Biol., 15, 2008
3D2S
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CRYSTAL STRUCTURE OF MBNL1 TANDEM ZINC FINGER 3 AND 4 DOMAIN IN COMPLEX WITH CGCUGU RNA
分子名称:5'-R(*CP*GP*CP*UP*GP*U)-3', Muscleblind-like protein 1, ZINC ION
著者Teplova, M., Patel, D.J.
登録日2008-05-08
公開日2008-12-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1.
Nat.Struct.Mol.Biol., 15, 2008
3DLB
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CRYSTAL STRUCTURE OF THE GUIDE-STRAND-CONTAINING ARGONAUTE PROTEIN SILENCING COMPLEX
分子名称:argonaute, DNA (5'-D(*DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DA)-3')
著者Wang, Y., Sheng, G., Patel, D.J.
登録日2008-06-26
公開日2008-09-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the guide-strand-containing argonaute silencing complex.
Nature, 456, 2008
3DLH
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CRYSTAL STRUCTURE OF THE GUIDE-STRAND-CONTAINING ARGONAUTE PROTEIN SILENCING COMPLEX
分子名称:Argonaute, DNA (5'-D(DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DAP*DGP*DGP*DTP*DTP*DGP*DTP*DAP*DTP*DAP*DGP*DT)-3'), MAGNESIUM ION, ...
著者Wang, Y., Sheng, G., Patel, D.J.
登録日2008-06-27
公開日2008-09-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the guide-strand-containing argonaute silencing complex.
Nature, 456, 2008
3F73
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ALIGNMENT OF GUIDE-TARGET SEED DUPLEX WITHIN AN ARGONAUTE SILENCING COMPLEX
分子名称:ARGONAUTE, DNA (5'-D(P*DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DAP*DGP*DGP*DTP*DTP*DGP*DTP*DA*DTP*DAP*DGP*DT)-3'), RNA (5'-R(*UP*AP*UP*AP*CP*AP*A*CP*UP*CP*AP*CP*UP*AP*CP*CP*UP*CP*GP*U)-3'), ...
著者Wang, Y., Li, H., Sheng, G., Juranek, S., Tuschl, T., Patel, D.J.
登録日2008-11-07
公開日2008-12-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex.
Nature, 456, 2008
3GII
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DPO4 EXTENSION TERNARY COMPLEX WITH DISORDERED A OPPOSITE AN OXOG IN ANTI CONFORMATION
分子名称:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DA))-3', 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', ...
著者Rechkoblit, O., Malinina, L., Patel, D.J.
登録日2009-03-05
公開日2009-05-19
最終更新日2011-12-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3GIJ
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DPO4 EXTENSION TERNARY COMPLEX WITH OXOG(SYN)-A(ANTI) AND OXOG(ANTI)-A(SYN) PAIRS
分子名称:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DA))-3', 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', ...
著者Rechkoblit, O., Malinina, L., Patel, D.J.
登録日2009-03-05
公開日2009-05-19
最終更新日2011-12-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3GIK
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DPO4 EXTENSION TERNARY COMPLEX WITH THE OXOG(ANTI)-C(ANTI) PAIR
分子名称:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(DOC))-3', 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', ...
著者Rechkoblit, O., Malinina, L., Patel, D.J.
登録日2009-03-05
公開日2009-05-19
最終更新日2011-12-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3GIL
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DPO4 EXTENSION TERNARY COMPLEX WITH OXOG(ANTI)-T(ANTI) PAIR
分子名称:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DT))-3', 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', ...
著者Rechkoblit, O., Malinina, L., Patel, D.J.
登録日2009-03-05
公開日2009-05-19
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3GIM
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DPO4 EXTENSION TERNARY COMPLEX WITH OXOG(ANTI)-G(SYN) PAIR
分子名称:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(DDG))-3', 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', ...
著者Rechkoblit, O., Malinina, L., Patel, D.J.
登録日2009-03-05
公開日2009-05-19
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3GL6
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CRYSTAL STRUCTURE OF JARID1A-PHD3 COMPLEXED WITH H3(1-9)K4ME3 PEPTIDE
分子名称:Histone demethylase JARID1A, Histone H3, ZINC ION
著者Wang, Z., Song, J., Patel, D.J.
登録日2009-03-11
公開日2009-05-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
3HJF
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CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE E546 MUTANT PROTEIN COMPLEXED WITH DNA GUIDE STRAND AND 15-NT RNA TARGET STRAND
分子名称:Argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', 5'-R(*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', ...
著者Wang, Y., Li, H., Sheng, G., Patel, D.J.
登録日2009-05-21
公開日2009-10-06
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.056 Å)
主引用文献Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
3HK2
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CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE N478 MUTANT PROTEIN COMPLEXED WITH DNA GUIDE STRAND AND 19-NT RNA TARGET STRAND
分子名称:Argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', 5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', ...
著者Wang, Y., Li, H., Sheng, G., Patel, D.J.
登録日2009-05-22
公開日2009-10-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
3HM9
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CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE COMPLEXED WITH DNA GUIDE STRAND AND 19-NT RNA TARGET STRAND
分子名称:Argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', 5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', ...
著者Wang, Y., Li, H., Sheng, G., Patel, D.J.
登録日2009-05-28
公開日2009-10-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
3HO1
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CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE N546 MUTANT PROTEIN COMPLEXED WITH DNA GUIDE STRAND AND 12-NT RNA TARGET STRAND
分子名称:argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*T*AP*GP*T)-3', 5'-R(P*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', ...
著者Wang, Y., Li, H., Sheng, G., Patel, D.J.
登録日2009-06-01
公開日2009-10-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
3HVR
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CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE COMPLEXED WITH DNA GUIDE STRAND AND 19-NT RNA TARGET STRAND WITH TWO MG2+ AT THE CLEAVAGE SITE
分子名称:Argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*TP*GP*AP*TP*AP*GP*T)-3', 5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', ...
著者Wang, Y., Li, H., Sheng, G., Patel, D.J.
登録日2009-06-16
公開日2009-10-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.211 Å)
主引用文献Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
3HXM
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STRUCTURE OF AN ARGONAUTE COMPLEXED WITH GUIDE DNA AND TARGET RNA DUPLEX CONTAINING TWO MISMATCHES.
分子名称:Argonaute, DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), RNA (5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*UP*CP*AP*CP*UP*AP*CP*CP*UP*CP*GP*U)-3'), ...
著者Wang, Y., Li, H., Sheng, G., Patel, D.J.
登録日2009-06-21
公開日2009-10-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
3K94
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CRYSTAL STRUCTURE OF THIAMIN PYROPHOSPHOKINASE FROM GEOBACILLUS THERMODENITRIFICANS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET GTR2
分子名称:Thiamin pyrophosphokinase
著者Kuzin, A., Su, M., Seetharaman, J., Janjua, J., Xiao, R., Patel, D.J., Ciccosanti, C., Lee, D., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
登録日2009-10-15
公開日2010-02-09
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Northeast Structural Genomics Consortium Target GtR2
To be Published
3KHG
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DPO4 EXTENSION TERNARY COMPLEX WITH MISINSERTED A OPPOSITE THE 2-AMINOFLUORENE-GUANINE [AF]G LESION
分子名称:DNA polymerase IV, 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DA))-3', 5'-D(*C*CP*TP*AP*AP*CP*GP*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', ...
著者Rechkoblit, O., Malinina, L., Patel, D.J.
登録日2009-10-30
公開日2010-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4.
Nat.Struct.Mol.Biol., 17, 2010