Author results

4RLI
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CRYSTAL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE (DHODH) WITH DH03A048
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Zhu, L., Ren, X., Zhu, J., Li, H.
Deposit date:2014-10-17
Release date:2015-11-04
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048
TO BE PUBLISHED
4RR4
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CRYSTAL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE (DHODH) WITH DH03A367
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Zhu, L., Ren, X., Zhu, J., Li, H.
Deposit date:2014-11-06
Release date:2015-11-25
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A367
TO BE PUBLISHED
5EGG
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CRYSTAL STRUCTURE OF HUMAN UBIQUITIN-CONJUGATING ENZYME UBCH5C
Descriptor:Ubiquitin-conjugating enzyme E2 D3
Authors:Zhu, L., Li, H., Wu, F., Zhu, J.
Deposit date:2015-10-27
Release date:2016-11-02
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c
Acta Pharm Sin B, 7, 2017
5GNV
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STRUCTURE OF PSD-95/MAP1A COMPLEX REVEALS UNIQUE TARGET RECOGNITION MODE OF MAGUK GK DOMAIN
Descriptor:Disks large homolog 4, Microtubule-associated protein 1A, SULFATE ION
Authors:Shang, Y., Xia, Y., Zhu, R., Zhu, J.
Deposit date:2016-07-25
Release date:2017-08-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain
Biochem. J., 474, 2017
3JBH
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TWO HEAVY MEROMYOSIN INTERACTING-HEADS MOTIFS FLEXIBLE DOCKED INTO TARANTULA THICK FILAMENT 3D-MAP ALLOWS IN DEPTH STUDY OF INTRA- AND INTERMOLECULAR INTERACTIONS
Descriptor:MYOSIN 2 HEAVY CHAIN STRIATED MUSCLE, MYOSIN 2 ESSENTIAL LIGHT CHAIN STRIATED MUSCLE, MYOSIN 2 REGULATORY LIGHT CHAIN STRIATED MUSCLE
Authors:Alamo, L., Qi, D., Wriggers, W., Pinto, A., Zhu, J., Bilbao, A., Gillilan, R.E., Hu, S., Padron, R.
Deposit date:2015-09-01
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis.
J. Mol. Biol., 428, 2016
4G5S
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STRUCTURE OF LGN GL3/GALPHAI3 COMPLEX
Descriptor:Guanine nucleotide-binding protein G(k) subunit alpha, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
1T48
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ALLOSTERIC INHIBITION OF PROTEIN TYROSINE PHOSPHATASE 1B
Descriptor:Protein-tyrosine phosphatase, non-receptor type 1, 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID DIMETHYLAMIDE
Authors:Wiesmann, C., Barr, K.J., Kung, J., Zhu, J., Shen, W., Fahr, B.J., Zhong, M., Erlanson, D.A., Taylor, L., Randal, M., McDowell, R.S., Hansen, S.K.
Deposit date:2004-04-28
Release date:2004-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Allosteric inhibition of protein tyrosine phosphatase 1B
Nat.Struct.Mol.Biol., 11, 2004
1T49
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ALLOSTERIC INHIBITION OF PROTEIN TYROSINE PHOSPHATASE 1B
Descriptor:Protein-tyrosine phosphatase, non-receptor type 1, MAGNESIUM ION, ...
Authors:Wiesmann, C., Barr, K.J., Kung, J., Zhu, J., Shen, W., Fahr, B.J., Zhong, M., Taylor, L., Randal, M., McDowell, R.S., Hansen, S.K.
Deposit date:2004-04-28
Release date:2004-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Allosteric inhibition of protein tyrosine phosphatase 1B.
Nat.Struct.Mol.Biol., 11, 2004
1T4J
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ALLOSTERIC INHIBITION OF PROTEIN TYROSINE PHOSPHATASE 1B
Descriptor:Protein-tyrosine phosphatase, non-receptor type 1, 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID [4-(THIAZOL-2-YLSULFAMOYL)-PHENYL]-AMIDE
Authors:Wiesmann, C., Barr, K.J., Kung, J., Zhu, J., Shen, W., Fahr, B.J., Zhong, M., Taylor, L., Randal, M., McDowell, R.S., Hansen, S.K.
Deposit date:2004-04-29
Release date:2004-07-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Allosteric inhibition of protein tyrosine phosphatase 1B
Nat.Struct.Mol.Biol., 11, 2004
2P5Y
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS HB8 UDP-GLUCOSE 4-EPIMERASE COMPLEX WITH NAD
Descriptor:UDP-glucose 4-epimerase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Fu, Z.-Q., Chen, L., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Zhu, J., Swindell, J.T., Chrzas, J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-16
Release date:2007-04-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD
To be Published
2P62
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CRYSTAL STRUCTURE OF HYPOTHETICAL PROTEIN PH0156 FROM PYROCOCCUS HORIKOSHII OT3
Descriptor:Hypothetical protein PH0156
Authors:Fu, Z.-Q., Chen, L., Zhu, J., Swindell, J.T., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Chrzas, J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-16
Release date:2007-04-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of hypothetical protein PH0156 from Pyrococcus horikoshii OT3
To be Published
2P8T
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HYPOTHETICAL PROTEIN PH0730 FROM PYROCOCCUS HORIKOSHII OT3
Descriptor:Hypothetical protein PH0730
Authors:Chen, L., Zhao, M., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Zhu, J., Swindell, J.T., Fu, Z.-Q., Chrzas, J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-23
Release date:2007-04-24
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hypothetical protein PH0730 from Pyrococcus horikoshii OT3
To be Published
2P9M
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CRYSTAL STRUCTURE OF CONSERVED HYPOTHETICAL PROTEIN MJ0922 FROM METHANOCALDOCOCCUS JANNASCHII DSM 2661
Descriptor:Hypothetical protein MJ0922
Authors:Zhao, M., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Zhu, J., Swindell II, J.T., Chen, L., Fu, Z.-Q., Charz, J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-26
Release date:2007-07-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal structure of conserved hypothetical protein MJ0922 from Methanocaldococcus jannaschii DSM 2661
To be Published
2PH3
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CRYSTAL STRUCTURE OF 3-OXOACYL-[ACYL CARRIER PROTEIN] REDUCTASE TTHA0415 FROM THERMUS THERMOPHILUS
Descriptor:3-oxoacyl-[acyl carrier protein] reductase
Authors:Swindell II, J.T., Chen, L., Zhu, J., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Fu, Z.-Q., Chrzas, J., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-10
Release date:2007-05-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of 3-oxoacyl-[acyl carrier protein] reductase TTHA0415 from Thermus thermophilus
To be Published
2PH7
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CRYSTAL STRUCTURE OF AF2093 FROM ARCHAEOGLOBUS FULGIDUS
Descriptor:Uncharacterized protein AF_2093
Authors:Chang, J.C., Yang, H., Hwang, J., Zhu, J., Chen, L., Fu, Z.-Q., Xu, H., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2007-04-10
Release date:2007-05-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of AF2093 from Archaeoglobus fulgidus.
To be Published
2PHC
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CRYSTAL STRUCTURE OF CONSERVED UNCHARACTERIZED PROTEIN PH0987 FROM PYROCOCCUS HORIKOSHII
Descriptor:Uncharacterized protein PH0987
Authors:Swindell II, J.T., Chen, L., Zhu, J., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Fu, Z.-Q., Chrzas, J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-10
Release date:2007-05-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Crystal structure of conserved uncharacterized protein PH0987 from Pyrococcus horikoshii.
To be Published
2PW6
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CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN JW3007 FROM ESCHERICHIA COLI K12
Descriptor:Uncharacterized protein ygiD, ZINC ION
Authors:Newton, M.G., Takagi, Y., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokayama, S., Li, Y., Chen, L., Zhu, J., Ruble, J., Liu, Z.J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-10
Release date:2007-06-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of uncharacterized protein JW3007 from Escherichia coli K12.
To be Published
4G5O
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STRUCTURE OF LGN GL4/GALPHAI3(Q147L) COMPLEX
Descriptor:Guanine nucleotide-binding protein G(k) subunit alpha, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
4G5Q
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STRUCTURE OF LGN GL4/GALPHAI1 COMPLEX
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
4G5R
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STRUCTURE OF LGN GL4/GALPHAI3 COMPLEX
Descriptor:Guanine nucleotide-binding protein G(k) subunit alpha, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Method:X-RAY DIFFRACTION (3.481 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
4H6J
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IDENTIFICATION OF CYS 255 IN HIF-1 AS A NOVEL SITE FOR DEVELOPMENT OF COVALENT INHIBITORS OF HIF-1 /ARNT PASB DOMAIN PROTEIN-PROTEIN INTERACTION.
Descriptor:HYPOXIA INDUCIBLE FACTOR 1-ALPHA, ARYL HYDROCARBON NUCLEAR TRANSLOCATOR
Authors:Cardoso, R., Love, R.A., Nilsson, C., Bergqvist, S., Nowlin, D., Yan, J., Liu, K., Zhu, J., Chen, P., Deng, Y.-L., Dyson, H.J., Greig, M.J., Brooun, A.
Deposit date:2012-09-19
Release date:2012-12-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Identification of Cys255 in HIF-1 alpha as a novel site for development of covalent inhibitors of HIF-1 alpha /ARNT PasB domain protein-protein interaction.
Protein Sci., 21, 2012
4HJW
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CRYSTAL STRUCTURE OF METARHIZIUM ANISOPLIAE IDCASE IN APO FORM
Descriptor:Uracil-5-carboxylate decarboxylase, ZINC ION
Authors:Xu, S., Zhu, J., Ding, J.
Deposit date:2012-10-14
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HK5
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE IN APO FORM
Descriptor:Uracil-5-carboxylate decarboxylase, ZINC ION
Authors:Xu, S., Zhu, J., Ding, J.
Deposit date:2012-10-15
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HK6
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE IN COMPLEX WITH 5-NITRO-URACIL
Descriptor:Uracil-5-carboxylate decarboxylase, ZINC ION, 5-nitrouracil
Authors:Xu, S., Zhu, J., Ding, J.
Deposit date:2012-10-15
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HK7
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE IN COMPLEX WITH URACIL
Descriptor:Uracil-5-carboxylate decarboxylase, ZINC ION, URACIL
Authors:Xu, S., Zhu, J., Ding, J.
Deposit date:2012-10-15
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.189 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013