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4RK8
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CRYSTAL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE (DHODH) WITH DH03A356
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Zhu, L., Ren, X., Zhu, J., Li, H.
Deposit date:2014-10-12
Release date:2015-11-11
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A356
TO BE PUBLISHED
4RKA
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CRYSTAL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE (DHODH) WITH DH03A347
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Zhu, L., Ren, X., Zhu, J., Li, H.
Deposit date:2014-10-12
Release date:2015-11-11
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A347
TO BE PUBLISHED
4RLI
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CRYSTAL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE (DHODH) WITH DH03A048
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Zhu, L., Ren, X., Zhu, J., Li, H.
Deposit date:2014-10-17
Release date:2015-11-04
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048
TO BE PUBLISHED
4RR4
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CRYSTAL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE (DHODH) WITH DH03A367
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Zhu, L., Ren, X., Zhu, J., Li, H.
Deposit date:2014-11-06
Release date:2015-11-25
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A367
TO BE PUBLISHED
5EGG
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CRYSTAL STRUCTURE OF HUMAN UBIQUITIN-CONJUGATING ENZYME UBCH5C
Descriptor:Ubiquitin-conjugating enzyme E2 D3
Authors:Zhu, L., Li, H., Wu, F., Zhu, J.
Deposit date:2015-10-27
Release date:2016-11-02
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c
Acta Pharm Sin B, 7, 2017
5GNV
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STRUCTURE OF PSD-95/MAP1A COMPLEX REVEALS UNIQUE TARGET RECOGNITION MODE OF MAGUK GK DOMAIN
Descriptor:Disks large homolog 4, Microtubule-associated protein 1A, SULFATE ION
Authors:Shang, Y., Xia, Y., Zhu, R., Zhu, J.
Deposit date:2016-07-25
Release date:2017-08-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain
Biochem. J., 474, 2017
3JBH
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TWO HEAVY MEROMYOSIN INTERACTING-HEADS MOTIFS FLEXIBLE DOCKED INTO TARANTULA THICK FILAMENT 3D-MAP ALLOWS IN DEPTH STUDY OF INTRA- AND INTERMOLECULAR INTERACTIONS
Descriptor:MYOSIN 2 HEAVY CHAIN STRIATED MUSCLE, MYOSIN 2 ESSENTIAL LIGHT CHAIN STRIATED MUSCLE, MYOSIN 2 REGULATORY LIGHT CHAIN STRIATED MUSCLE
Authors:Alamo, L., Qi, D., Wriggers, W., Pinto, A., Zhu, J., Bilbao, A., Gillilan, R.E., Hu, S., Padron, R.
Deposit date:2015-09-01
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis.
J. Mol. Biol., 428, 2016
4G5S
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STRUCTURE OF LGN GL3/GALPHAI3 COMPLEX
Descriptor:Guanine nucleotide-binding protein G(k) subunit alpha, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
5XZR
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THE ATOMIC STRUCTURE OF SHP2 E76A MUTANT IN COMPLEX WITH ALLOSTERIC INHIBITOR 9B
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, 4-(3-phenylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3-thiazol-2-amine
Authors:Li, D., Xie, J., Zhu, J., Liu, C.
Deposit date:2017-07-13
Release date:2017-12-13
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment.
J. Med. Chem., 60, 2017
6KOB
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X-RAY STRUCTURE OF THE PROTON-PUMPING CYTOCHROME AA3-600 MENAQUINOL OXIDASE FROM BACILLUS SUBTILIS
Descriptor:AA3-600 quinol oxidase subunit I, Quinol oxidase subunit 2, AA3-600 quinol oxidase subunit IIII, ...
Authors:Xu, J., Ding, Z., Liu, B., Li, J., Gennis, R.B., Zhu, J.
Deposit date:2019-08-09
Release date:2020-01-15
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site.
Proc.Natl.Acad.Sci.USA, 117, 2020
6KOC
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X-RAY STRUCTURE OF THE PROTON-PUMPING CYTOCHROME AA3-600 MENAQUINOL OXIDASE FROM BACILLUS SUBTILIS COMPLEXED WITH 3-IODO-N-OXO-2-HEPTYL-4-HYDROXYQUINOLINE
Descriptor:AA3-600 quinol oxidase subunit I, Quinol oxidase subunit 2, AA3-600 quinol oxidase subunit IIII, ...
Authors:Xu, J., Ding, Z., Liu, B., Li, J., Gennis, R.B., Zhu, J.
Deposit date:2019-08-09
Release date:2020-01-15
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site.
Proc.Natl.Acad.Sci.USA, 117, 2020
6KOE
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X-RAY STRUCTURE OF THE PROTON-PUMPING CYTOCHROME AA3-600 MENAQUINOL OXIDASE FROM BACILLUS SUBTILIS
Descriptor:AA3-600 quinol oxidase subunit I, Quinol oxidase subunit 2, AA3-600 quinol oxidase subunit IIII, ...
Authors:Xu, J., Ding, Z., Liu, B., Li, J., Gennis, R.B., Zhu, J.
Deposit date:2019-08-09
Release date:2020-01-15
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site.
Proc.Natl.Acad.Sci.USA, 117, 2020
1T48
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ALLOSTERIC INHIBITION OF PROTEIN TYROSINE PHOSPHATASE 1B
Descriptor:Protein-tyrosine phosphatase, non-receptor type 1, 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID DIMETHYLAMIDE
Authors:Wiesmann, C., Barr, K.J., Kung, J., Zhu, J., Shen, W., Fahr, B.J., Zhong, M., Erlanson, D.A., Taylor, L., Randal, M., McDowell, R.S., Hansen, S.K.
Deposit date:2004-04-28
Release date:2004-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Allosteric inhibition of protein tyrosine phosphatase 1B
Nat.Struct.Mol.Biol., 11, 2004
1T49
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ALLOSTERIC INHIBITION OF PROTEIN TYROSINE PHOSPHATASE 1B
Descriptor:Protein-tyrosine phosphatase, non-receptor type 1, MAGNESIUM ION, ...
Authors:Wiesmann, C., Barr, K.J., Kung, J., Zhu, J., Shen, W., Fahr, B.J., Zhong, M., Taylor, L., Randal, M., McDowell, R.S., Hansen, S.K.
Deposit date:2004-04-28
Release date:2004-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Allosteric inhibition of protein tyrosine phosphatase 1B.
Nat.Struct.Mol.Biol., 11, 2004
1T4J
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ALLOSTERIC INHIBITION OF PROTEIN TYROSINE PHOSPHATASE 1B
Descriptor:Protein-tyrosine phosphatase, non-receptor type 1, 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID [4-(THIAZOL-2-YLSULFAMOYL)-PHENYL]-AMIDE
Authors:Wiesmann, C., Barr, K.J., Kung, J., Zhu, J., Shen, W., Fahr, B.J., Zhong, M., Taylor, L., Randal, M., McDowell, R.S., Hansen, S.K.
Deposit date:2004-04-29
Release date:2004-07-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Allosteric inhibition of protein tyrosine phosphatase 1B
Nat.Struct.Mol.Biol., 11, 2004
2P5Y
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS HB8 UDP-GLUCOSE 4-EPIMERASE COMPLEX WITH NAD
Descriptor:UDP-glucose 4-epimerase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Fu, Z.-Q., Chen, L., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Zhu, J., Swindell, J.T., Chrzas, J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-16
Release date:2007-04-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD
To be Published
2P62
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CRYSTAL STRUCTURE OF HYPOTHETICAL PROTEIN PH0156 FROM PYROCOCCUS HORIKOSHII OT3
Descriptor:Hypothetical protein PH0156
Authors:Fu, Z.-Q., Chen, L., Zhu, J., Swindell, J.T., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Chrzas, J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-16
Release date:2007-04-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of hypothetical protein PH0156 from Pyrococcus horikoshii OT3
To be Published
2P8T
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HYPOTHETICAL PROTEIN PH0730 FROM PYROCOCCUS HORIKOSHII OT3
Descriptor:Hypothetical protein PH0730
Authors:Chen, L., Zhao, M., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Zhu, J., Swindell, J.T., Fu, Z.-Q., Chrzas, J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-23
Release date:2007-04-24
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hypothetical protein PH0730 from Pyrococcus horikoshii OT3
To be Published
2P9M
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CRYSTAL STRUCTURE OF CONSERVED HYPOTHETICAL PROTEIN MJ0922 FROM METHANOCALDOCOCCUS JANNASCHII DSM 2661
Descriptor:Hypothetical protein MJ0922
Authors:Zhao, M., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Zhu, J., Swindell II, J.T., Chen, L., Fu, Z.-Q., Charz, J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-26
Release date:2007-07-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal structure of conserved hypothetical protein MJ0922 from Methanocaldococcus jannaschii DSM 2661
To be Published
2PH3
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CRYSTAL STRUCTURE OF 3-OXOACYL-[ACYL CARRIER PROTEIN] REDUCTASE TTHA0415 FROM THERMUS THERMOPHILUS
Descriptor:3-oxoacyl-[acyl carrier protein] reductase
Authors:Swindell II, J.T., Chen, L., Zhu, J., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Fu, Z.-Q., Chrzas, J., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-10
Release date:2007-05-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of 3-oxoacyl-[acyl carrier protein] reductase TTHA0415 from Thermus thermophilus
To be Published
2PH7
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CRYSTAL STRUCTURE OF AF2093 FROM ARCHAEOGLOBUS FULGIDUS
Descriptor:Uncharacterized protein AF_2093
Authors:Chang, J.C., Yang, H., Hwang, J., Zhu, J., Chen, L., Fu, Z.-Q., Xu, H., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2007-04-10
Release date:2007-05-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of AF2093 from Archaeoglobus fulgidus.
To be Published
2PHC
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CRYSTAL STRUCTURE OF CONSERVED UNCHARACTERIZED PROTEIN PH0987 FROM PYROCOCCUS HORIKOSHII
Descriptor:Uncharacterized protein PH0987
Authors:Swindell II, J.T., Chen, L., Zhu, J., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Fu, Z.-Q., Chrzas, J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-10
Release date:2007-05-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Crystal structure of conserved uncharacterized protein PH0987 from Pyrococcus horikoshii.
To be Published
2PW6
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CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN JW3007 FROM ESCHERICHIA COLI K12
Descriptor:Uncharacterized protein ygiD, ZINC ION
Authors:Newton, M.G., Takagi, Y., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokayama, S., Li, Y., Chen, L., Zhu, J., Ruble, J., Liu, Z.J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-10
Release date:2007-06-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of uncharacterized protein JW3007 from Escherichia coli K12.
To be Published
4G5O
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STRUCTURE OF LGN GL4/GALPHAI3(Q147L) COMPLEX
Descriptor:Guanine nucleotide-binding protein G(k) subunit alpha, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
4G5Q
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STRUCTURE OF LGN GL4/GALPHAI1 COMPLEX
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
171588
건을2020-11-25부터공개중