Author results

3C8K
  • Download 3c8k
  • View 3c8k
Molmil generated image of 3c8k
THE CRYSTAL STRUCTURE OF LY49C BOUND TO H-2KB
Descriptor:H-2 class I histocompatibility antigen, K-B alpha chain, beta-2 microglobulin, ...
Authors:Deng, L., Mariuzza, R.A.
Deposit date:2008-02-12
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.
J.Biol.Chem., 283, 2008
3D34
  • Download 3d34
  • View 3d34
Molmil generated image of 3d34
STRUCTURE OF THE F-SPONDIN DOMAIN OF MINDIN
Descriptor:Spondin-2, NICKEL (II) ION, CALCIUM ION
Authors:Li, Y., Mariuzza, R.A.
Deposit date:2008-05-09
Release date:2009-02-17
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule.
Embo J., 28, 2009
3FF7
  • Download 3ff7
  • View 3ff7
Molmil generated image of 3ff7
STRUCTURE OF NK CELL RECEPTOR KLRG1 BOUND TO E-CADHERIN
Descriptor:Epithelial cadherin, Killer cell lectin-like receptor subfamily G member 1, ACETIC ACID
Authors:Li, Y., Mariuzza, R.A.
Deposit date:2008-12-02
Release date:2009-07-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition.
Immunity, 31, 2009
3FF8
  • Download 3ff8
  • View 3ff8
Molmil generated image of 3ff8
STRUCTURE OF NK CELL RECEPTOR KLRG1 BOUND TO E-CADHERIN
Descriptor:Epithelial cadherin, Killer cell lectin-like receptor subfamily G member 1, CALCIUM ION
Authors:Li, Y., Mariuzza, R.A.
Deposit date:2008-12-02
Release date:2009-07-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition.
Immunity, 31, 2009
3FF9
  • Download 3ff9
  • View 3ff9
Molmil generated image of 3ff9
STRUCTURE OF NK CELL RECEPTOR KLRG1
Descriptor:Killer cell lectin-like receptor subfamily G member 1
Authors:Li, Y., Mariuzza, R.A.
Deposit date:2008-12-02
Release date:2009-07-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition.
Immunity, 31, 2009
3G39
  • Download 3g39
  • View 3g39
Molmil generated image of 3g39
STRUCTURE OF A LAMPREY VARIABLE LYMPHOCYTE RECEPTOR
Descriptor:Variable lymphocyte receptor VLRB.2D
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2009-02-02
Release date:2009-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3G3A
  • Download 3g3a
  • View 3g3a
Molmil generated image of 3g3a
STRUCTURE OF A LAMPREY VARIABLE LYMPHOCYTE RECEPTOR IN COMPLEX WITH A PROTEIN ANTIGEN
Descriptor:Variable lymphocyte receptor VLRB.2D, Lysozyme C
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2009-02-02
Release date:2009-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3G3B
  • Download 3g3b
  • View 3g3b
Molmil generated image of 3g3b
STRUCTURE OF A LAMPREY VARIABLE LYMPHOCYTE RECEPTOR MUTANT IN COMPLEX WITH A PROTEIN ANTIGEN
Descriptor:variable lymphocyte receptor VLRB.2D, Lysozyme C
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2009-02-02
Release date:2009-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3L6F
  • Download 3l6f
  • View 3l6f
Molmil generated image of 3l6f
STRUCTURE OF MHC CLASS II MOLECULE HLA-DR1 COMPLEXED WITH PHOSPHOPEPTIDE MART-1
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Li, Y., Mariuzza, R.A.
Deposit date:2009-12-23
Release date:2010-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for the Presentation of Tumor-Associated MHC Class II-Restricted Phosphopeptides to CD4(+) T Cells.
J.Mol.Biol., 399, 2010
3M18
  • Download 3m18
  • View 3m18
Molmil generated image of 3m18
CRYSTAL STRUCTURE OF VARIABLE LYMPHOCYTE RECEPTOR VLRA.R2.1 IN COMPLEX WITH HEN EGG LYSOZYME
Descriptor:Variable lymphocyte receptor A diversity region, Lysozyme C, PHOSPHATE ION
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2010-03-04
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A structural basis for antigen recognition by the T cell-like lymphocytes of sea lamprey.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M19
  • Download 3m19
  • View 3m19
Molmil generated image of 3m19
CRYSTAL STRUCTURE OF VARIABLE LYMPHOCYTE RECEPTOR VLRA.R5.1
Descriptor:Variable lymphocyte receptor A diversity region
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2010-03-04
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A structural basis for antigen recognition by the T cell-like lymphocytes of sea lamprey.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MC0
  • Download 3mc0
  • View 3mc0
Molmil generated image of 3mc0
CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN G (SEG) IN COMPLEX WITH A MOUSE T-CELL RECEPTOR BETA CHAIN
Descriptor:variable beta 8.2 mouse T cell receptor, Enterotoxin SEG, ACETATE ION
Authors:Fernandez, M.M., Cho, S., Robinson, H., Mariuzza, R.A., Malchiodi, E.L.
Deposit date:2010-03-26
Release date:2010-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.
J.Biol.Chem., 286, 2011
3O6F
  • Download 3o6f
  • View 3o6f
Molmil generated image of 3o6f
CRYSTAL STRUCTURE OF A HUMAN AUTOIMMUNE TCR MS2-3C8 BOUND TO MHC CLASS II SELF-LIGAND MBP/HLA-DR4
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ...
Authors:Yin, Y., Li, Y., Martin, R., Mariuzza, R.A.
Deposit date:2010-07-29
Release date:2011-03-02
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection.
Embo J., 30, 2011
3OWE
  • Download 3owe
  • View 3owe
Molmil generated image of 3owe
CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN G (SEG) IN COMPLEX WITH A HIGH AFFINITY MUTANT MOUSE T-CELL RECEPTOR CHAIN
Descriptor:Beta-chain, Enterotoxin SEG
Authors:Fernandez, M.M., Cho, S., Robinson, H., Mariuzza, R.A., Malchiodi, M.L.
Deposit date:2010-09-17
Release date:2010-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.
J.Biol.Chem., 286, 2011
3T0E
  • Download 3t0e
  • View 3t0e
Molmil generated image of 3t0e
CRYSTAL STRUCTURE OF A COMPLETE TERNARY COMPLEX OF T CELL RECEPTOR, PEPTIDE-MHC AND CD4
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ...
Authors:Yin, Y., Mariuzza, R.A.
Deposit date:2011-07-20
Release date:2012-03-07
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4.
Proc.Natl.Acad.Sci.USA, 109, 2012
4E41
  • Download 4e41
  • View 4e41
Molmil generated image of 4e41
STRUCTURAL BASIS FOR THE RECOGNITION OF MUTANT SELF BY A TUMOR-SPECIFIC, MHC CLASS II-RESTRICTED T CELL RECEPTOR G4
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Deng, L., Langley, R.J., Wang, Q., Topalian, S.L., Mariuzza, R.A.
Deposit date:2012-03-11
Release date:2012-08-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
4E42
  • Download 4e42
  • View 4e42
Molmil generated image of 4e42
STRUCTURAL BASIS FOR THE RECOGNITION OF MUTANT SELF BY A TUMOR-SPECIFIC, MHC CLASS II-RESTRICTED T CELL RECEPTOR G4
Descriptor:T cell receptor G4 alpha chain, T cell receptor G4 beta chain, CHLORIDE ION, ...
Authors:Deng, L., Langley, R.J., Wang, Q., Topalian, S.L., Mariuzza, R.A.
Deposit date:2012-03-11
Release date:2012-08-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
4K5U
  • Download 4k5u
  • View 4k5u
Molmil generated image of 4k5u
RECOGNITION OF THE BG-H ANTIGEN BY A LAMPREY VARIABLE LYMPHOCYTE RECEPTOR
Descriptor:Variable lymphocyte receptor, BETA-D-GALACTOSE
Authors:Luo, M., Velikovsky, C.A., Yang, X.B., Mariuzza, R.A.
Deposit date:2013-04-15
Release date:2013-06-26
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor.
J.Biol.Chem., 288, 2013
4K79
  • Download 4k79
  • View 4k79
Molmil generated image of 4k79
RECOGNITION OF THE THOMSEN-FRIEDENREICH ANTIGEN BY A LAMPREY VARIABLE LYMPHOCYTE RECEPTOR
Descriptor:Variable lymphocyte receptor, BETA-D-GALACTOSE, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE
Authors:Luo, M., Velikovsky, C.A., Yang, X.B., Mariuzza, R.A.
Deposit date:2013-04-16
Release date:2013-06-26
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor.
J.Biol.Chem., 288, 2013
4XVJ
  • Download 4xvj
  • View 4xvj
Molmil generated image of 4xvj
STRUCTURE OF THE HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 ANTIGENIC 2 REGION 412-423 BOUND TO THE BROADLY NEUTRALIZING ANTIBODY HC33.1
Descriptor:HCV E2 antigen, antibody heavy chain variable domain, antibody light chain variable domain
Authors:Li, Y., Mariuzza, R.A.
Deposit date:2015-01-27
Release date:2015-03-11
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for penetration of the glycan shield of hepatitis C virus e2 glycoprotein by a broadly neutralizing human antibody.
J.Biol.Chem., 290, 2015
4Z0X
  • Download 4z0x
  • View 4z0x
Molmil generated image of 4z0x
STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 ANTIGENIC REGION 434-446 BOUND TO THE BROADLY NEUTRALIZING ANTIBODY HC26AM
Descriptor:Antibody HC26AM light chain variable domain, Antibody HC26AM heavy chain variable domain, HCV E2 Antigen (residues 432-446)
Authors:Rangarajan, S., Mariuzza, R.A.
Deposit date:2015-03-26
Release date:2016-07-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Hepatitis C Virus Envelope glycoprotein E2 antigenic region 434-446 bound to the broadly neutralizing antibody HC26AM
To Be Published
4ZSO
  • Download 4zso
  • View 4zso
Molmil generated image of 4zso
CRYSTAL STRUCTURE OF A COMPLEX BETWEEN B7-H6, A TUMOR CELL LIGAND FOR NATURAL CYTOTOXICITY RECEPTOR NKP30, AND AN INHIBITORY ANTIBODY
Descriptor:Antibody Light Chain, Antibody Heavy Chain, Natural cytotoxicity triggering receptor 3 ligand 1, ...
Authors:Xu, X., Li, Y., Mariuzza, R.A.
Deposit date:2015-05-13
Release date:2016-05-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a complex between B7-H6, a tumor cell ligand for natural cytotoxicity receptor NKp30, and an inhibitory antibody
to be published
5D2L
  • Download 5d2l
  • View 5d2l
Molmil generated image of 5d2l
CRYSTAL STRUCTURE OF TCR C7 IN COMPLEX WITH HCMV NLV EPITOPE PRESENTED BY HLA-A2
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Gao, M., Mariuzza, R.A.
Deposit date:2015-08-05
Release date:2015-10-07
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.511 Å)
Cite:Crystal structure of TCR C7 in complex with HCMV NLV epitope presented by HLA-A2
J.Biol.Chem., 2015
5TEZ
  • Download 5tez
  • View 5tez
Molmil generated image of 5tez
TCR F50 RECGONIZING M1-HLA-A2
Descriptor:GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Yang, X., Mariuzza, R.A.
Deposit date:2016-09-23
Release date:2017-09-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for clonal diversity of the human T-cell response to a dominant influenza virus epitope.
J. Biol. Chem., 292, 2017
1FV1
  • Download 1fv1
  • View 1fv1
Molmil generated image of 1fv1
STRUCTURAL BASIS FOR THE BINDING OF AN IMMUNODOMINANT PEPTIDE FROM MYELIN BASIC PROTEIN IN DIFFERENT REGISTERS BY TWO HLA-DR2 ALLELES
Descriptor:MAJOR HISTOCOMPATIBILITY COMPLEX ALPHA CHAIN, MAJOR HISTOCOMPATIBILITY COMPLEX BETA CHAIN, MYELIN BASIC PROTEIN, ...
Authors:Li, H., Mariuzza, A.R., Li, Y., Martin, R.
Deposit date:2000-09-18
Release date:2000-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins.
J.Mol.Biol., 304, 2000