2JQN | | SOLUTION NMR STRUCTURE OF CC0527 FROM CAULOBACTER CRESCENTUS. NORTHEAST STRUCTURAL GENOMICS TARGET CCR55 | | Descriptor: | Hypothetical protein | | Authors: | Aramini, J.M., Rossi, P., Moseley, H.N.B., Wang, D., Nwosu, C., Cunningham, K., Ma, L., Xiao, R., Liu, J., Baran, M.C., Swapna, G.V.T., Acton, T.B., Rost, B., Montelione, G.T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-06-05 | | Release date: | 2007-07-03 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of CC0527 from Caulobacter crescentus
To be Published
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2KT1 | | SOLUTION NMR STRUCTURE OF THE SH3 DOMAIN FROM THE P85BETA SUBUNIT OF PHOSPHATIDYLINOSITOL 3-KINASE FROM H.SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR5531E | | Descriptor: | Phosphatidylinositol 3-kinase regulatory subunit beta | | Authors: | Aramini, J.M., Ma, L., Schauder, C., Everett, J.K., Montelione, G.T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-01-15 | | Release date: | 2010-01-26 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of the SH3 Domain from the p85beta subunit of Phosphatidylinositol 3-kinase from H.sapiens, Northeast Structural Genomics Consortium Target HR5531E
To be Published
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4PXZ | | CRYSTAL STRUCTURE OF P2Y12 RECEPTOR IN COMPLEX WITH 2MESADP | | Descriptor: | P2Y purinoceptor 12, Soluble cytochrome b562, 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), ... | | Authors: | Zhang, J., Zhang, K., Gao, Z.G., Paoletta, S., Zhang, D., Han, G.W., Li, T., Ma, L., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR) | | Deposit date: | 2014-03-25 | | Release date: | 2014-04-30 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Agonist-bound structure of the human P2Y12 receptor
Nature, 509, 2014
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4PY0 | | CRYSTAL STRUCTURE OF P2Y12 RECEPTOR IN COMPLEX WITH 2MESATP | | Descriptor: | P2Y purinoceptor 12, Soluble cytochrome b562, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), ... | | Authors: | Zhang, J., Zhang, K., Gao, Z.G., Paoletta, S., Zhang, D., Han, G.W., Li, T., Ma, L., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR) | | Deposit date: | 2014-03-25 | | Release date: | 2014-04-30 | | Last modified: | 2017-08-16 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Agonist-bound structure of the human P2Y12 receptor
Nature, 509, 2014
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5JP2 | |
6JCN | | YEAST DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 | | Descriptor: | Dehydrodolichyl diphosphate synthase complex subunit NUS1, SULFATE ION | | Authors: | Ko, T.-P., Ma, J., Liu, W., Chen, C.-C., Guo, R.-T. | | Deposit date: | 2019-01-29 | | Release date: | 2019-06-19 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (1.998 Å) | | Cite: | Structural insights to heterodimeric cis-prenyltransferases through yeast dehydrodolichyl diphosphate synthase subunit Nus1.
Biochem.Biophys.Res.Commun., 515, 2019
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5DIL | | CRYSTAL STRUCTURE OF THE EFFECTOR DOMAIN OF THE NS1 PROTEIN FROM INFLUENZA VIRUS B | | Descriptor: | Non-structural protein 1, IODIDE ION | | Authors: | Guan, R., Hamilton, K., Ma, L., Montelione, G.T. | | Deposit date: | 2015-09-01 | | Release date: | 2016-08-10 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | A Second RNA-Binding Site in the NS1 Protein of Influenza B Virus.
Structure, 24, 2016
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1R57 | | NMR SOLUTION STRUCTURE OF A GCN5-LIKE PUTATIVE N-ACETYLTRANSFERASE FROM STAPHYLOCOCCUS AUREUS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ZR31 | | Descriptor: | conserved hypothetical protein | | Authors: | Cort, J.R., Acton, T.B., Ma, L., Xiao, R.B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2003-10-09 | | Release date: | 2004-03-09 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Structure of an acetyl-CoA binding protein from Staphylococcus aureus representing a novel subfamily of GCN5-related N-acetyltransferase-like proteins.
J.STRUCT.FUNCT.GENOM., 9, 2008
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1ZTS | | SOLUTION STRUCTURE OF BACILLUS SUBTILIS PROTEIN YQBG: NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR215 | | Descriptor: | Hypothetical protein yqbG | | Authors: | Liu, G., Shen, Y., Xiao, R., Acton, T., Ma, L., Joachimiak, A., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2005-05-27 | | Release date: | 2005-07-12 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | NMR structure of protein yqbG from Bacillus subtilis reveals a novel alpha-helical protein fold.
Proteins, 62, 2006
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2H5M | | NMR SOLUTION STRUCTURE OF A GCN5-LIKE PUTATIVE N-ACETYLTRANSFERASE FROM STAPHYLOCOCCUS AUREUS COMPLEXED WITH ACETYL-COA. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ZR31 | | Descriptor: | Acetyltransferase, GNAT family, ACETYL COENZYME *A | | Authors: | Cort, J.R., Ramelot, T.A., Acton, T.B., Ma, L., Xiao, R.B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-05-26 | | Release date: | 2006-11-28 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Structure of an acetyl-CoA binding protein from Staphylococcus aureus representing a novel subfamily of GCN5-related N-acetyltransferase-like proteins
J.Struct.Funct.Genom., 9, 2008
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2LP6 | | REFINED SOLUTION NMR STRUCTURE OF THE 50S RIBOSOMAL PROTEIN L35AE FROM PYROCOCCUS FURIOSUS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET (NESG) PFR48 | | Descriptor: | 50S ribosomal protein L35Ae | | Authors: | Snyder, D.A., Aramini, J.M., Yu, B., Huang, Y.J., Xiao, R., Cort, J.R., Shastry, R., Ma, L., Liu, J., Rost, B., Acton, T.B., Kennedy, M.A., Montelione, G.T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-02-02 | | Release date: | 2012-02-15 | | Last modified: | 2012-06-20 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the ribosomal protein RP-L35Ae from Pyrococcus furiosus.
Proteins, 80, 2012
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3UIV | | HUMAN SERUM ALBUMIN-MYRISTATE-AMANTADINE HYDROCHLORIDE COMPLEX | | Descriptor: | Serum albumin, MYRISTIC ACID, (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine | | Authors: | Yang, F., Ma, Z., Ma, L., Yang, G. | | Deposit date: | 2011-11-06 | | Release date: | 2012-11-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of the drug-binding specificity of human serum albumin
TO BE PUBLISHED
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6JCJ | | STRUCTURE OF CROLIBULIN IN COMPLEX WITH TUBULIN | | Descriptor: | Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ... | | Authors: | Zhang, Z., Yang, J. | | Deposit date: | 2019-01-29 | | Release date: | 2019-03-13 | | Last modified: | 2019-03-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design.
Biochem. Biophys. Res. Commun., 511, 2019
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2JRT | | NMR SOLUTION STRUCTURE OF THE PROTEIN CODED BY GENE RHOS4_12090 OF RHODOBACTER SPHAEROIDES. NORTHEAST STRUCTURAL GENOMICS TARGET RHR5 | | Descriptor: | Uncharacterized protein | | Authors: | Wang, L., Chen, C., Nwosu, C., Cunningham, K., Owens, L., Ma, L., Xiao, R., Liu, J., Baran, M.C., Swapna, G., Acton, T.B., Rost, B., Montelione, G.T., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-06-28 | | Release date: | 2007-08-21 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of the protein coded by gene RHOS4_12090 of Rhodobacter sphaeroides.
To be Published
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4HZL | |
4Q0X | |
3RK0 | | X-RAY CRYSTAL STRUCTURE OF THE PUTATIVE N-TYPE ATP PYROPHOSPHATASE (PF0828) IN COMPLEX WITH AMP FROM PYROCOCCUS FURIOSUS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET PFR23 | | Descriptor: | N-type ATP pyrophosphatase superfamily, ADENOSINE MONOPHOSPHATE | | Authors: | Forouhar, F., Saadat, N., Hussain, M., Seetharaman, J., Janjua, J., Xiao, R., Cunningham, K., Ma, L., Shastry, R., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2011-04-16 | | Release date: | 2011-05-11 | | Last modified: | 2012-01-11 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A large conformational change in the putative ATP pyrophosphatase PF0828 induced by ATP binding.
Acta Crystallogr.,Sect.F, 67, 2011
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3RK1 | | 'X-RAY CRYSTAL STRUCTURE OF THE PUTATIVE N-TYPE ATP PYROPHOSPHATASE (PF0828) IN COMPLEX WITH ATP FROM PYROCOCCUS FURIOSUS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET PFR23 | | Descriptor: | N-type ATP pyrophosphatase superfamily, ADENOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION | | Authors: | Forouhar, F., Seetharaman, J., Janjua, J., Xiao, R., Cunningham, K., Ma, L., Shastry, R., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2011-04-16 | | Release date: | 2011-05-11 | | Last modified: | 2012-01-11 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A large conformational change in the putative ATP pyrophosphatase PF0828 induced by ATP binding.
Acta Crystallogr.,Sect.F, 67, 2011
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4IVS | | CRYSTAL STRUCTURE OF BACE1 WITH ITS INHIBITOR | | Descriptor: | Beta-secretase 1, N-{N-[4-(acetylamino)-3,5-dichlorobenzyl]carbamimidoyl}-2-(6-cyano-1H-indol-1-yl)acetamide | | Authors: | Chen, T.T., Li, L., Chen, W.Y., Xu, Y.C. | | Deposit date: | 2013-01-23 | | Release date: | 2013-11-13 | | Method: | X-RAY DIFFRACTION (2.636 Å) | | Cite: | Virtual screening and structure-based discovery of indole acylguanidines as potent beta-secretase (BACE1) inhibitors
Molecules, 18, 2013
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4IVT | | CRYSTAL STRUCTURE OF BACE1 WITH ITS INHIBITOR | | Descriptor: | Beta-secretase 1, N-{N-[4-(acetylamino)-3,5-dichlorobenzyl]carbamimidoyl}-2-(1H-indol-1-yl)acetamide, SULFATE ION | | Authors: | Chen, T.T., Li, L., Chen, W.Y., Xu, Y.C. | | Deposit date: | 2013-01-23 | | Release date: | 2013-11-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Virtual screening and structure-based discovery of indole acylguanidines as potent beta-secretase (BACE1) inhibitors
Molecules, 18, 2013
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5JHG | | CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE HUMAN RHOA AND THE DH/PH DOMAIN OF HUMAN ARHGEF11 | | Descriptor: | Rho guanine nucleotide exchange factor 11, Transforming protein RhoA, GLYCEROL | | Authors: | Wang, R., Chen, Q., Zhang, H., Yan, Z., Li, J., Miao, L., Wang, F. | | Deposit date: | 2016-04-21 | | Release date: | 2017-04-26 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and ARHGEF11
To Be Published
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1YWL | |
2JN7 | | NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER411 | | Descriptor: | protein yfjZ | | Authors: | Tian, F., Zhao, L., Jiang, M., Cunningham, K., Ma, L., Xiao, R., Liu, J., Baran, M., Swapna, G.V.T., Acton, T.B., Rost, B., Montelione, G.T., Prestegard, J.H., Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-12-28 | | Release date: | 2007-01-09 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of E.Coli hypothetical protein YFJZ
To be Published
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4QXM | | CRYSTAL STRUCTURE OF THE INHA:GSK_SB713 COMPLEX | | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, N-(2-chloro-4-fluorobenzyl)-4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]benzamide | | Authors: | Gulten, G., Sacchettini, J.C. | | Deposit date: | 2014-07-21 | | Release date: | 2015-07-22 | | Last modified: | 2016-04-27 | | Method: | X-RAY DIFFRACTION (2.196 Å) | | Cite: | N-Benzyl-4-((heteroaryl)methyl)benzamides: A New Class of Direct NADH-Dependent 2-trans Enoyl-Acyl Carrier Protein Reductase (InhA) Inhibitors with Antitubercular Activity.
Chemmedchem, 11, 2016
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5INW | | STRUCTURE OF REACTION LOOP CLEAVED LAMPREY ANGIOTENSINOGEN | | Descriptor: | Putative angiotensinogen, C-terminal peptide of Putative angiotensinogen, SULFATE ION | | Authors: | Wei, H., Zhou, A. | | Deposit date: | 2016-03-08 | | Release date: | 2016-10-05 | | Last modified: | 2016-12-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism
J.Biol.Chem., 291, 2016
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