Author results

5XM5
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CRYSTAL STRUCTURE OF ZINC BINDING PROTEIN ZINT AT 1.49 ANGSTROM FROM E. COLI
Descriptor:Metal-binding protein ZinT, ZINC ION, SODIUM ION
Authors:Chen, J., Wang, L., Guo, J., Xu, Y.
Deposit date:2017-05-12
Release date:2017-05-31
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.493 Å)
Cite:Crystal structure of Zinc binding protein ZinT at 1.49 Angstrom from E. coli
To Be Published
5YHQ
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CRYO-EM STRUCTURE OF CVA6 VLP
Descriptor:Capsid protein VP1, Capsid protein VP3, capsid protein VP0
Authors:Chen, J., Zhang, C., Huang, Z., Cong, Y.
Deposit date:2017-09-29
Release date:2017-10-25
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A 3.0-Angstrom Resolution Cryo-Electron Microscopy Structure and Antigenic Sites of Coxsackievirus A6-Like Particles.
J. Virol., 92, 2018
1HA0
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HEMAGGLUTININ PRECURSOR HA0
Descriptor:PROTEIN (HEMAGGLUTININ PRECURSOR), beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chen, J., Ho Lee, K., Steinhauer, D.A., Stevens, D.J., Skehel, J.J., Wiley, D.C.
Deposit date:1998-10-08
Release date:1998-10-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation.
Cell(Cambridge,Mass.), 95, 1998
1QU1
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CRYSTAL STRUCTURE OF EHA2 (23-185)
Descriptor:PROTEIN (INFLUENZA RECOMBINANT HA2 CHAIN)
Authors:Chen, J., Skehel, J.J., Wiley, D.C.
Deposit date:1999-07-05
Release date:2000-01-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil.
Proc.Natl.Acad.Sci.USA, 96, 1999
3BU7
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CRYSTAL STRUCTURE AND BIOCHEMICAL CHARACTERIZATION OF GDOSP, A GENTISATE 1,2-DIOXYGENASE FROM SILICIBACTER POMEROYI
Descriptor:Gentisate 1,2-dioxygenase, FE (II) ION
Authors:Chen, J., Wang, M.Z., Zhu, G.Y., Zhang, X.C., Rao, Z.H.
Deposit date:2008-01-02
Release date:2008-08-12
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure and mutagenic analysis of GDOsp, a gentisate 1,2-dioxygenase from Silicibacter pomeroyi.
Protein Sci., 17, 2008
5H11
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CRYSTAL STRUCTURE OF ZEBRAFISH SEC10
Descriptor:Uncharacterized protein, BROMIDE ION
Authors:Chen, J., Yamagata, A., Fukai, S.
Deposit date:2016-10-07
Release date:2017-02-01
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.732 Å)
Cite:Crystal structure of Sec10, a subunit of the exocyst complex
Sci Rep, 7, 2017
5I65
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PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS NONSTRUCTURAL PROTEIN 7 ALPHA (NSP7 ALPHA)
Descriptor:Nonstructural proteins ORF1a
Authors:Chen, J., Xu, X.
Deposit date:2016-02-16
Release date:2017-02-22
Method:SOLUTION NMR
Cite:Structure of porcine reproductive and respiratory syndrome virus nonstructural protein 7 alpha (nsp7 alpha)
To Be Published
5VT0
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ESCHERICHIA COLI 6S RNA DERIVATIVE IN COMPLEX WITH ESCHERICHIA COLI RNA POLYMERASE SIGMA70-HOLOENZYME
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Chen, J., Darst, S.A.
Deposit date:2017-05-15
Release date:2017-11-01
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:6S RNA Mimics B-Form DNA to Regulate Escherichia coli RNA Polymerase.
Mol. Cell, 68, 2017
5Y9Q
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CRYSTAL STRUCTURE OF THE CCPE REGULATORY DOMAIN AT 1.95 ANGSTROM FROM STAPHYLOCOCCUS AUREUS
Descriptor:Carbon catabolite responsive regulator
Authors:Chen, J., Wang, L., Shang, F., Xu, Y.
Deposit date:2017-08-27
Release date:2017-09-06
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (1.953 Å)
Cite:Structural and Biochemical Analysis of the Citrate-Responsive Mechanism of the Regulatory Domain of Catabolite Control Protein E from Staphylococcus aureus
Biochemistry, 57, 2018
5YXC
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CRYSTAL STRUCTURE OF ZINC BINDING PROTEIN ZINT IN COMPLEX WITH CITRATE FROM E. COLI
Descriptor:Metal-binding protein ZinT, ZINC ION, CITRIC ACID
Authors:Chen, J., Wang, L., Shang, F., Xu, Y.
Deposit date:2017-12-04
Release date:2017-12-20
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (1.763 Å)
Cite:Crystal structure of E. coli ZinT with one zinc-binding mode and complexed with citrate
Biochem. Biophys. Res. Commun., 500, 2018
5Z72
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CRYSTAL STRUCTURE OF CCPC REGULATORY DOMAIN IN COMPLEX WITH CITRATE FROM BACILLUS AMYLOLIQUEFACIENS
Descriptor:CcpC, SODIUM ION, CITRATE ANION
Authors:Chen, J., Wang, L., Shang, F., Xu, Y.
Deposit date:2018-01-26
Release date:2018-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanistic insights from the crystal structures of a catabolite control protein C on citrate-responsive mechanism
To Be Published
5Z7H
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CRYSTAL STRUCTURE OF CCPE REGULATORY DOMAIN IN CITRATE-BOUND FORM FROM STAPHYLOCCOCUS AUREUS
Descriptor:LysR family transcriptional regulator, CITRATE ANION
Authors:Chen, J., Wang, L., Shang, F., Xu, Y.
Deposit date:2018-01-28
Release date:2018-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Citrate-responsive mechanism of catabolite control protein E from Staphyloccocus aureus
To Be Published
5ZZO
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CRYSTAL STRUCTURE OF CCPE REGULATORY DOMAIN IN COMPLEX WITH CITRATE FROM STAPHYLOCCOCUS AUREUS
Descriptor:LysR family transcriptional regulator, CITRATE ANION
Authors:Chen, J., Wang, L., Shang, F., Xu, Y.
Deposit date:2018-06-04
Release date:2018-06-20
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Biochemical Analysis of the Citrate-Responsive Mechanism of the Regulatory Domain of Catabolite Control Protein E from Staphylococcus aureus
Biochemistry, 57, 2018
6XEZ
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STRUCTURE OF SARS-COV-2 REPLICATION-TRANSCRIPTION COMPLEX BOUND TO NSP13 HELICASE - NSP13(2)-RTC
Descriptor:nsp12, nsp8, nsp7, ...
Authors:Chen, J., Malone, B., Llewellyn, E.C., Campbell, E.A., Darst, S.A.
Deposit date:2020-06-14
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex.
Biorxiv, 2020
3LDA
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YEAST RAD51 H352Y FILAMENT INTERFACE MUTANT
Descriptor:DNA repair protein RAD51, CHLORIDE ION
Authors:Villanueva, N.L., Chen, J., Morrical, S.W., Rould, M.A.
Deposit date:2010-01-12
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into the mechanism of Rad51 recombinase from the structure and properties of a filament interface mutant.
Nucleic Acids Res., 38, 2010
4XAX
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS CARD IN COMPLEX WITH THE THERMUS AQUATICUS RNA POLYMERASE BETA1 DOMAIN
Descriptor:DNA-directed RNA polymerase subunit beta domain 1, CarD, 1,2-ETHANEDIOL
Authors:Chen, J., Bae, B., Campbell, E.A., Darst, S.A.
Deposit date:2014-12-15
Release date:2015-09-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.
Elife, 4, 2015
4MSU
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HUMAN GKRP BOUND TO AMG-6861 AND SORBITOL-6-PHOSPHATE
Descriptor:Glucokinase regulatory protein, 1,1,1,3,3,3-hexafluoro-2-{4-[4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol, D-SORBITOL-6-PHOSPHATE, ...
Authors:Ashton, K.S., Andrews, K.L., Bryan, M.C., Chen, J., Chen, K., Chen, M., Chmait, S., Croghan, M., Cupples, R., Fotsch, C., Helmering, J., Jordan, S.R., Kurzeja, R.J., Michelsen, K., Pennington, L.D., Poon, S.F., Sivits, G., Van, G., Vonderfecht, S.L., Wahl, R.C., Zhang, J., Lloyd, D.J., Hale, C., St Jean, D.J.
Deposit date:2013-09-18
Release date:2014-03-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept.
J.Med.Chem., 57, 2014
6L6W
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THE STRUCTURE OF SCOE WITH INTERMEDIATE
Descriptor:ScoE protein, FE (II) ION, (3R)-3-[[(1R)-1,2-bis(oxidanyl)-2-oxidanylidene-ethyl]amino]butanoic acid, ...
Authors:Chen, T.Y., Chen, J., Zhou, J., Chang, W.
Deposit date:2019-10-29
Release date:2020-03-04
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases.
Angew.Chem.Int.Ed.Engl., 59, 2020
6L6X
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THE STRUCTURE OF SCOE WITH SUBSTRATE
Descriptor:ScoE protein, (3~{R})-3-(2-hydroxy-2-oxoethylamino)butanoic acid, FE (II) ION, ...
Authors:Chen, T.Y., Chen, J., Zhou, J., Chang, W.
Deposit date:2019-10-29
Release date:2020-03-04
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases.
Angew.Chem.Int.Ed.Engl., 59, 2020
6L86
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THE STRUCTURE OF SFAA
Descriptor:Taurine catabolism dioxygenase, FE (II) ION, (2S)-2-hydroxybutanedioic acid, ...
Authors:Chen, T.Y., Chen, J., Zhou, J., Chang, W.
Deposit date:2019-11-05
Release date:2020-03-04
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases.
Angew.Chem.Int.Ed.Engl., 59, 2020
3PCU
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CRYSTAL STRUCTURE OF HUMAN RETINOIC X RECEPTOR ALPHA LIGAND-BINDING DOMAIN COMPLEXED WITH LX0278 AND SRC1 PEPTIDE
Descriptor:Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2, 2-[(2S)-6-(2-methylbut-3-en-2-yl)-7-oxo-2,3-dihydro-7H-furo[3,2-g]chromen-2-yl]propan-2-yl acetate
Authors:Zhang, H., Zhang, Y., Shen, H., Chen, J., Li, C., Chen, L., Hu, L., Jiang, H., Shen, X.
Deposit date:2010-10-22
Release date:2011-11-16
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice.
Plos One, 7, 2012
3N3Y
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CRYSTAL STRUCTURE OF THYMIDYLATE SYNTHASE X (THYX) FROM HELICOBACTER PYLORI WITH FAD AND DUMP AT 2.31A RESOLUTION
Descriptor:Thymidylate synthase thyX, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Wang, K., Wang, Q., Chen, J., Chen, L., Jiang, H., Shen, X.
Deposit date:2010-05-21
Release date:2011-05-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.307 Å)
Cite:Structure, Enzymatic Characterization and Inhibitor Discovery of Thymidylate Synthase X (ThyX) from Helicobacter pylori Strain SS1
To be Published
3P30
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CRYSTAL STRUCTURE OF THE CLUSTER II FAB 1281 IN COMPLEX WITH HIV-1 GP41 ECTODOMAIN
Descriptor:HIV-1 gp41, 1281 Fab light chain, 1281 Fab heavy chain
Authors:Frey, G., Chen, J., Rits-Volloch, S., Freeman, M.M., Zolla-Pazner, S., Chen, B.
Deposit date:2010-10-04
Release date:2010-11-17
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies.
Nat.Struct.Mol.Biol., 17, 2010
3R29
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CRYSTAL STRUCTURE OF RXRALPHA LIGAND-BINDING DOMAIN COMPLEXED WITH COREPRESSOR SMRT2
Descriptor:Retinoic acid receptor RXR-alpha, Nuclear receptor corepressor 2
Authors:Zhang, H., Chen, L., Chen, J., Jiang, H., Shen, X.
Deposit date:2011-03-14
Release date:2011-05-25
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for retinoic x receptor repression on the tetramer.
J.Biol.Chem., 286, 2011
3R2A
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CRYSTAL STRUCTURE OF RXRALPHA LIGAND-BINDING DOMAIN COMPLEXED WITH COREPRESSOR SMRT2 AND ANTAGONIST RHEIN
Descriptor:Retinoic acid receptor RXR-alpha, Nuclear receptor corepressor 2, 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
Authors:Zhang, H., Chen, L., Chen, J., Jiang, H., Shen, X.
Deposit date:2011-03-14
Release date:2011-05-25
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for retinoic x receptor repression on the tetramer.
J.Biol.Chem., 286, 2011
167132
數據於2020-07-29公開中