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3DLL
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BU of 3dll by Molmil
The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Descriptor: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Wilson, D.N, Schluenzen, F, Harms, J.M, Starosta, A.L, Connell, S.R, Fucini, P.
Deposit date:2008-06-27
Release date:2008-09-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Proc.Natl.Acad.Sci.Usa, 105, 2008
1Y69
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BU of 1y69 by Molmil
RRF domain I in complex with the 50S ribosomal subunit from Deinococcus radiodurans
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L16, 50S ribosomal protein L27, ...
Authors:Wilson, D.N, Schluenzen, F, Harms, J.M, Yoshida, T, Ohkubo, T, Albrecht, R, Buerger, J, Kobayashi, Y, Fucini, P.
Deposit date:2004-12-04
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:X-ray crystallography on ribosome recycling: mechanism of binding and action of RRF on the 50S ribosomal subunit
EMBO J., 24, 2005
6HTQ
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BU of 6htq by Molmil
Stringent response control by a bifunctional RelA enzyme in the presence and absence of the ribosome
Descriptor: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Wilson, D.N, Abdelshahid, M.
Deposit date:2018-10-04
Release date:2019-10-23
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural Basis for Regulation of the Opposing (p)ppGpp Synthetase and Hydrolase within the Stringent Response Orchestrator Rel.
Cell Rep, 32, 2020
7NRC
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BU of 7nrc by Molmil
Structure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A- and P-tRNA and eIF5A
Descriptor: 18S rRNA (1771-MER), 25S rRNA (3184-MER), 40S ribosomal protein S0-A, ...
Authors:Pochopien, A.A, Beckert, B, Wilson, D.N.
Deposit date:2021-03-03
Release date:2021-05-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of Gcn1 bound to stalled and colliding 80S ribosomes.
Proc.Natl.Acad.Sci.USA, 118, 2021
8BN3
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BU of 8bn3 by Molmil
Yeast 80S, ES7s delta, eIF5A, Stm1 containing
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
Authors:Dimitrova-Paternoga, L, Paternoga, H, Wilson, D.N.
Deposit date:2022-11-12
Release date:2024-01-10
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Evolving precision: rRNA expansion segment 7S modulates translation velocity and accuracy in eukaryal ribosomes.
Nucleic Acids Res., 52, 2024
4V6W
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BU of 4v6w by Molmil
Structure of the D. melanogaster 80S ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 2S ribosomal RNA, ...
Authors:Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R.
Deposit date:2013-02-27
Release date:2014-07-09
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structures of the human and Drosophila 80S ribosome.
Nature, 497, 2013
4V5H
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BU of 4v5h by Molmil
E.Coli 70s Ribosome Stalled During Translation Of Tnac Leader Peptide.
Descriptor: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Seidelt, B, Innis, C.A, Wilson, D.N, Gartmann, M, Armache, J, Villa, E, Trabuco, L.G, Becker, T, Mielke, T, Schulten, K, Steitz, T.A, Beckmann, R.
Deposit date:2009-10-26
Release date:2014-07-09
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural insight into nascent polypeptide chain-mediated translational stalling.
Science, 326, 2009
6ENF
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BU of 6enf by Molmil
Cryo-EM structure of a polyproline-stalled ribosome in the absence of EF-P
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Huter, P, Arenz, S, Wilson, D.N.
Deposit date:2017-10-04
Release date:2017-11-22
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
Mol. Cell, 68, 2017
7P7T
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BU of 7p7t by Molmil
PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state III
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2021-07-20
Release date:2022-02-23
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
7P7Q
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BU of 7p7q by Molmil
E. faecalis 70S ribosome bound by PoxtA-EQ2, high-resolution combined volume
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2021-07-20
Release date:2022-02-23
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
7P7S
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BU of 7p7s by Molmil
PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state II
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2021-07-20
Release date:2022-02-23
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
7P7U
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BU of 7p7u by Molmil
E. faecalis 70S ribosome with P-tRNA, state IV
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2021-07-20
Release date:2022-02-23
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
7P7R
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BU of 7p7r by Molmil
PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state I
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2021-07-20
Release date:2022-03-23
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
4V6I
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BU of 4v6i by Molmil
Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein RACK1 (RACK1), ...
Authors:Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R.
Deposit date:2010-10-12
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
5FDU
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BU of 5fdu by Molmil
Crystal structure of the Metalnikowin I antimicrobial peptide bound to the Thermus thermophilus 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Seefeldt, A.C, Graf, M, Perebaskine, N, Nguyen, F, Arenz, S, Mardirossian, M, Scocchi, M, Wilson, D.N, Innis, C.A.
Deposit date:2015-12-16
Release date:2016-01-27
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
Nucleic Acids Res., 44, 2016
4V61
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BU of 4v61 by Molmil
Homology model for the Spinach chloroplast 30S subunit fitted to 9.4A cryo-EM map of the 70S chlororibosome.
Descriptor: 16S rRNA, 23S rRNA, 4.8S rRNA, ...
Authors:Sharma, M.R, Wilson, D.N, Datta, P.P, Barat, C, Schluenzen, F, Fucini, P, Agrawal, R.K.
Deposit date:2007-11-09
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins
Proc.Natl.Acad.Sci.Usa, 104, 2007
4V5M
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BU of 4v5m by Molmil
tRNA tranlocation on the 70S ribosome: the pre-translocational translocation intermediate TI(PRE)
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Ratje, A.H, Loerke, J, Mikolajka, A, Bruenner, M, Hildebrand, P.W, Starosta, A.L, Doenhoefer, A, Connell, S.R, Fucini, P, Mielke, T, Whitford, P.C, Onuchic, J.N, Yu, Y, Sanbonmatsu, K.Y, Hartmann, R.K, Penczek, P.A, Wilson, D.N, Spahn, C.M.T.
Deposit date:2010-10-01
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
4V6U
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BU of 4v6u by Molmil
Promiscuous behavior of proteins in archaeal ribosomes revealed by cryo-EM: implications for evolution of eukaryotic ribosomes
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10P, ...
Authors:Armache, J.-P, Anger, A.M, Marquez, V, Frankenberg, S, Froehlich, T, Villa, E, Berninghausen, O, Thomm, M, Arnold, G.J, Beckmann, R, Wilson, D.N.
Deposit date:2012-08-09
Release date:2014-07-09
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Promiscuous behaviour of archaeal ribosomal proteins: Implications for eukaryotic ribosome evolution.
Nucleic Acids Res., 41, 2013
4V6X
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BU of 4v6x by Molmil
Structure of the human 80S ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R.
Deposit date:2013-02-27
Release date:2014-07-09
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structures of the human and Drosophila 80S ribosome.
Nature, 497, 2013
8QCQ
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BU of 8qcq by Molmil
B. subtilis ApdA-stalled ribosomal complex
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Morici, M, Wilson, D.N.
Deposit date:2023-08-28
Release date:2024-03-20
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity.
Nat Commun, 15, 2024
8QBT
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BU of 8qbt by Molmil
E. coli ApdP-stalled ribosomal complex
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ...
Authors:Morici, M, Wilson, D.N.
Deposit date:2023-08-25
Release date:2024-03-20
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity.
Nat Commun, 15, 2024
8QOA
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BU of 8qoa by Molmil
Structure of SecM-stalled Escherichia coli 70S ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S16, ...
Authors:Gersteuer, F, Morici, M, Wilson, D.N.
Deposit date:2023-09-28
Release date:2024-03-20
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2 Å)
Cite:The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome.
Nat Commun, 15, 2024
8R6C
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BU of 8r6c by Molmil
70S Escherichia coli ribosome with Paenilamicin B2 bound with A- and P-site tRNA.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S16, ...
Authors:Koller, T.O, Wilson, D.N.
Deposit date:2023-11-22
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis.
Biorxiv, 2024
8R8M
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BU of 8r8m by Molmil
70S Escherichia coli ribosome with Paenilamicin B2 bound with hybrid A/P- and hybrid P/E-tRNA.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S16, ...
Authors:Koller, T.O, Wilson, D.N.
Deposit date:2023-11-29
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis.
Biorxiv, 2024
4V7E
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BU of 4v7e by Molmil
Model of the small subunit RNA based on a 5.5 A cryo-EM map of Triticum aestivum translating 80S ribosome
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S10E, ...
Authors:Barrio-Garcia, C, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R.
Deposit date:2013-11-22
Release date:2014-07-09
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion.
Nature, 506, 2014

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