Author results

1XGU
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STRUCTURE FOR ANTIBODY HYHEL-63 Y33F MUTANT COMPLEXED WITH HEN EGG LYSOZYME
Descriptor:antibody kappa light chain, antibody kappa heavy chain, Lysozyme C
Authors:Li, Y., Huang, Y., Swaminathan, C.P., Smith-Gill, S.J., Mariuzza, R.A.
Deposit date:2004-09-17
Release date:2005-09-06
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
Structure, 13, 2005
1XXG
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN G
Descriptor:enterotoxin, SULFATE ION
Authors:Fernandez, M.M., Bhattacharya, S., Malchiodi, E.L., Mariuzza, R.A.
Deposit date:2004-11-05
Release date:2006-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of Staphylococcal Enterotoxin G and binding affinity to T-cell receptor and MHC class II molecule
To be Published
1YCK
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CRYSTAL STRUCTURE OF HUMAN PEPTIDOGLYCAN RECOGNITION PROTEIN (PGRP-S)
Descriptor:Peptidoglycan recognition protein
Authors:Guan, R., Wang, Q., Sundberg, E.J., Mariuzza, R.A.
Deposit date:2004-12-22
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human peptidoglycan recognition protein S (PGRP-S) at 1.70 A resolution.
J.Mol.Biol., 347, 2005
1YWO
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PHOSPHOLIPASE CGAMMA1 SH3 IN COMPLEX WITH A SLP-76 MOTIF
Descriptor:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1, Lymphocyte cytosolic protein 2
Authors:Deng, L., Velikovsky, C.A., Swaminathan, C.P., Cho, S., Mariuzza, R.A.
Deposit date:2005-02-18
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural Basis for Recognition of the T Cell Adaptor Protein SLP-76 by the SH3 Domain of Phospholipase Cgamma1
J.Mol.Biol., 352, 2005
1YWP
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PHOSPHOLIPASE CGAMMA1 SH3
Descriptor:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1
Authors:Deng, L., Velikovsky, C.A., Swaminathan, C.P., Cho, S., Mariuzza, R.A.
Deposit date:2005-02-18
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for Recognition of the T Cell Adaptor Protein SLP-76 by the SH3 Domain of Phospholipase Cgamma1
J.Mol.Biol., 352, 2005
1ZGL
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CRYSTAL STRUCTURE OF 3A6 TCR BOUND TO MBP/HLA-DR2A
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, major histocompatibility complex, ...
Authors:Li, Y., Huang, Y., Lue, J., Quandt, J.A., Martin, R., Mariuzza, R.A.
Deposit date:2005-04-21
Release date:2005-10-18
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule.
Embo J., 24, 2005
2APB
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CRYSTAL STRUCTURE OF THE S54N VARIANT OF MURINE T CELL RECEPTOR VBETA 8.2 DOMAIN
Descriptor:T-cell receptor beta chain V, MALONIC ACID
Authors:Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J.
Deposit date:2005-08-16
Release date:2006-03-21
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2APF
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CRYSTAL STRUCTURE OF THE A52V/S54N/K66E VARIANT OF THE MURINE T CELL RECEPTOR V BETA 8.2 DOMAIN
Descriptor:T cell receptor beta chain V, MALONIC ACID
Authors:Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J.
Deposit date:2005-08-16
Release date:2006-03-21
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2APH
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CRYSTAL STRUCTURE OF HUMAN PGRP-IALPHAC IN COMPLEX WITH MURAMYL PENTAPEPTIDE
Descriptor:Peptidoglycan recognition protein I-alpha, muramyl pentapeptide, SULFATE ION
Authors:Guan, R., Roychowdjury, A., Boons, G., Mariuzza, R.A.
Deposit date:2005-08-16
Release date:2006-06-27
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human peptidoglycan recognition protein I alpha bound to a muramyl pentapeptide from Gram-positive bacteria.
Protein Sci., 15, 2006
2APT
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CRYSTAL STRUCTURE OF THE G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V VARIANT OF THE MURINE T CELL RECEPTOR V BETA 8.2 DOMAIN
Descriptor:T-cell receptor beta chain V, MALONIC ACID
Authors:Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J.
Deposit date:2005-08-16
Release date:2006-03-21
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2APV
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CRYSTAL STRUCTURE OF THE G17E/A52V/S54N/Q72H/E80V/L81S/T87S/G96V VARIANT OF THE MURINE T CELL RECEPTOR V BETA 8.2 DOMAIN
Descriptor:T cell receptor beta chain V, MALONIC ACID
Authors:Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J.
Deposit date:2005-08-16
Release date:2006-03-21
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2APW
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CRYSTAL STRUCTURE OF THE G17E/A52V/S54N/K66E/E80V/L81S/T87S/G96V VARIANT OF THE MURINE T CELL RECEPTOR V BETA 8.2 DOMAIN
Descriptor:T cell receptor beta chain V, MALONIC ACID
Authors:Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J.
Deposit date:2005-08-16
Release date:2006-03-21
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2APX
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CRYSTAL STRUCTURE OF THE G17E/A52V/S54N/K66E/Q72H/E80V/L81S/T87S/G96V VARIANT OF THE MURINE T CELL RECEPTOR V BETA 8.2 DOMAIN
Descriptor:T cell receptor beta chain V, MALONIC ACID
Authors:Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J.
Deposit date:2005-08-16
Release date:2006-03-21
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2AQ1
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CRYSTAL STRUCTURE OF T-CELL RECEPTOR V BETA DOMAIN VARIANT COMPLEXED WITH SUPERANTIGEN SEC3 MUTANT
Descriptor:T-cell receptor beta chain V, Enterotoxin type C-3
Authors:Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J.
Deposit date:2005-08-17
Release date:2006-03-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2AQ2
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CRYSTAL STRUCTURE OF T-CELL RECEPTOR V BETA DOMAIN VARIANT COMPLEXED WITH SUPERANTIGEN SEC3 MUTANT
Descriptor:T-CELL RECEPTOR BETA CHAIN V, Enterotoxin type C-3, ZINC ION, ...
Authors:Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J.
Deposit date:2005-08-17
Release date:2006-03-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2AQ3
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CRYSTAL STRUCTURE OF T-CELL RECEPTOR V BETA DOMAIN VARIANT COMPLEXED WITH SUPERANTIGEN SEC3
Descriptor:T-cell receptor beta chain V, Enterotoxin type C-3
Authors:Cho, S., Swaminathan, C.P., Yang, J., Kerzic, M.C., Guan, R., Kieke, M.C., Kranz, D.M., Mariuzza, R.A., Sundberg, E.J.
Deposit date:2005-08-17
Release date:2006-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2EAV
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CRYSTAL STRUCTURE OF THE C-TERMINAL PEPTIDOGLYCAN-BINDING DOMAIN OF HUMAN PEPTIDOGLYCAN RECOGNITION PROTEIN IBETA
Descriptor:Peptidoglycan recognition protein-I-beta, NICKEL (II) ION
Authors:Cho, S., Mariuzza, R.A.
Deposit date:2007-02-03
Release date:2007-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins
Proc.Natl.Acad.Sci.Usa, 104, 2007
2G9H
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN I (SEI) IN COMPLEX WITH A HUMAN MHC CLASS II MOLECULE
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Fernandez, M.M., Guan, R., Malchiodi, E.L., Mariuzza, R.A.
Deposit date:2006-03-06
Release date:2006-07-11
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule.
J.Biol.Chem., 281, 2006
2IAL
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STRUCTURAL BASIS FOR RECOGNITION OF MUTANT SELF BY A TUMOR-SPECIFIC, MHC CLASS II-RESTRICTED TCR
Descriptor:CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain
Authors:Deng, L., Langley, R.J., Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
2IAM
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STRUCTURAL BASIS FOR RECOGNITION OF MUTANT SELF BY A TUMOR-SPECIFIC, MHC CLASS II-RESTRICTED TCR
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Deng, L., Langley, R.J., Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
2IAN
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STRUCTURAL BASIS FOR RECOGNITION OF MUTANT SELF BY A TUMOR-SPECIFIC, MHC CLASS II-RESTRICTED TCR
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Deng, L., Langley, R.J., Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
2PTT
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STRUCTURE OF NK CELL RECEPTOR 2B4 (CD244) BOUND TO ITS LIGAND CD48
Descriptor:CD48 antigen, Natural killer cell receptor 2B4, SULFATE ION
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
2PTU
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STRUCTURE OF NK CELL RECEPTOR 2B4 (CD244)
Descriptor:Natural killer cell receptor 2B4
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
2PTV
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STRUCTURE OF NK CELL RECEPTOR LIGAND CD48
Descriptor:CD48 antigen
Authors:Deng, L., Velikovsky, C.A., Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
3C8J
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THE CRYSTAL STRUCTURE OF NATURAL KILLER CELL RECEPTOR LY49C
Descriptor:Natural killer cell receptor Ly49C
Authors:Deng, L., Mariuzza, R.A.
Deposit date:2008-02-12
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.
J.Biol.Chem., 283, 2008