1JWM

Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1(HA peptide 306-318) with the Superantigen SEC3

Summary for 1JWM

• Entry DOI: 10.2210/pdb1jwm/pdb
• Related: 1JWS 1JWU
• Descriptor: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DR-1 beta chain, HA peptide, ... (5 entities in total)
• Functional Keywords: hla-dr1 alpha subunit, hla-dr1 beta subunit, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane; Single-pass type I membrane protein: P01903 P04229; Secreted: P0A0L5
• Total number of polymer chains: 4
• Total formula weight: 72366.36

Authors

Sundberg, E.J.,Andersen, P.S.,Schlievert, P.M.,Karjalainen, K.,Mariuzza, R.A. (deposition date: 2001-09-04, release date: 2003-07-08, Last modification date: 2011-07-13)

• Primary citation: Sundberg, E.J.,Andersen, P.S.,Schlievert, P.M.,Karjalainen, K.,Mariuzza, R.A.; Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity maturation; Structure, 11:1151-1161, 2003; PubMed: 12962633; DOI: 10.1016/S0969-2126(03)00187-4

Experimental method

X-RAY DIFFRACTION (2.7 Å)