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1G7M
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92V)
Descriptor:ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J., Urrutia, M., Braden, B.C., Isern, J., Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1JND
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CRYSTAL STRUCTURE OF IMAGINAL DISC GROWTH FACTOR-2
Descriptor:Imaginal disc growth factor-2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Varela, P.F., Llera, A.S., Mariuzza, R.A., Tormo, J.
Deposit date:2001-07-23
Release date:2002-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster.
J.Biol.Chem., 277, 2002
1JNE
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CRYSTAL STRUCTURE OF IMAGINAL DISC GROWTH FACTOR-2
Descriptor:Imaginal disc growth factor-2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Varela, P.F., Llera, A.S., Mariuzza, R.A., Tormo, J.
Deposit date:2001-07-23
Release date:2002-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster.
J.Biol.Chem., 277, 2002
1JWM
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE MHC CLASS II MOLECULE HLA-DR1(HA PEPTIDE 306-318) WITH THE SUPERANTIGEN SEC3
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DR-1 beta chain, ...
Authors:Sundberg, E.J., Andersen, P.S., Schlievert, P.M., Karjalainen, K., Mariuzza, R.A.
Deposit date:2001-09-04
Release date:2003-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity maturation
Structure, 11, 2003
1JWS
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE MHC CLASS II MOLECULE HLA-DR1 (HA PEPTIDE 306-318) WITH THE SUPERANTIGEN SEC3 VARIANT 3B1
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DR-1 beta chain, ...
Authors:Sundberg, E.J., Andersen, P.S., Schlievert, P.M., Karjalainen, K., Mariuzza, R.A.
Deposit date:2001-09-05
Release date:2003-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity maturation
Structure, 11, 2003
1JWU
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE MHC CLASS II MOLECULE HLA-DR1 (HA PEPTIDE 306-318) WITH THE SUPERANTIGEN SEC3 VARIANT 3B2
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DR-1 beta chain, ...
Authors:Sundberg, E.J., Andersen, P.S., Schlievert, P.M., Karjalainen, K., Mariuzza, R.A.
Deposit date:2001-09-05
Release date:2003-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity maturation
Structure, 11, 2003
1KLG
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CRYSTAL STRUCTURE OF HLA-DR1/TPI(23-37, THR28-->ILE MUTANT) COMPLEXED WITH STAPHYLOCOCCAL ENTEROTOXIN C3 VARIANT 3B2 (SEC3-3B2)
Descriptor:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, DR-1 BETA CHAIN, ...
Authors:Sundberg, E.J., Sawicki, M.W., Andersen, P.S., Sidney, J., Sette, A., Mariuzza, R.A.
Deposit date:2001-12-11
Release date:2002-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
1KLU
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CRYSTAL STRUCTURE OF HLA-DR1/TPI(23-37) COMPLEXED WITH STAPHYLOCOCCAL ENTEROTOXIN C3 VARIANT 3B2 (SEC3-3B2)
Descriptor:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, DR-1 BETA CHAIN, ...
Authors:Sundberg, E.J., Sawicki, M.W., Andersen, P.S., Sidney, J., Sette, A., Mariuzza, R.A.
Deposit date:2001-12-12
Release date:2002-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
1KTK
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COMPLEX OF STREPTOCOCCAL PYROGENIC ENTEROTOXIN C (SPEC) WITH A HUMAN T CELL RECEPTOR BETA CHAIN (VBETA2.1)
Descriptor:Exotoxin type C, T-cell receptor beta chain
Authors:Sundberg, E.J., Li, H., Llera, A.S., McCormick, J.K., Tormo, J., Karjalainen, K., Schlievert, P.M., Mariuzza, R.A.
Deposit date:2002-01-16
Release date:2002-06-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.
Structure, 10, 2002
1L0X
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TCR BETA CHAIN COMPLEXED WITH STREPTOCOCCAL SUPERANTIGEN SPEA
Descriptor:14.3.d T cell receptor beta chain, Exotoxin type A, GLYCEROL
Authors:Li, H., Sundberg, E.J., Mariuzza, R.A.
Deposit date:2002-02-14
Release date:2002-04-03
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.
Structure, 10, 2002
1L0Y
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T CELL RECEPTOR BETA CHAIN COMPLEXED WITH SUPERANTIGEN SPEA SOAKED WITH ZINC
Descriptor:14.3.d T cell receptor beta chain, Exotoxin type A, ZINC ION, ...
Authors:Li, H., Sundberg, E.J., Mariuzza, R.A.
Deposit date:2002-02-14
Release date:2002-04-03
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.
Structure, 10, 2002
1NKO
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ENERGETIC AND STRUCTURAL BASIS OF SIALYLATED OLIGOSACCHARIDE RECOGNITION BY THE NATURAL KILLER CELL INHIBITORY RECEPTOR P75/AIRM1 OR SIGLEC-7
Descriptor:Sialic acid binding Ig-like lectin 7
Authors:Dimasi, N., Attril, H., van Aalten, D.M.F., Moretta, L., Biassoni, R., Mariuzza, R.A.
Deposit date:2003-01-03
Release date:2003-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1.
Acta Crystallogr.,Sect.D, 60, 2004
1P4L
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CRYSTAL STRUCTURE OF NK RECEPTOR LY49C MUTANT WITH ITS MHC CLASS I LIGAND H-2KB
Descriptor:MHC CLASS I H-2KB HEAVY CHAIN, Beta-2-microglobulin, Ovalbumin peptide, ...
Authors:Dam, J., Guan, R., Natarajan, K., Dimasi, N., Mariuzza, R.A.
Deposit date:2003-04-23
Release date:2003-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b).
Nat.Immunol., 4, 2003
1PYW
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HUMAN CLASS II MHC PROTEIN HLA-DR1 BOUND TO A DESIGNED PEPTIDE RELATED TO INFLUENZA VIRUS HEMAGGLUTININ, FVKQNA(MAA)AL, IN COMPLEX WITH STAPHYLOCOCCAL ENTEROTOXIN C3 VARIANT 3B2 (SEC3-3B2)
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DR-1 beta chain, ...
Authors:Zavala-Ruiz, Z., Sundberg, E.J., Stone, J.D., DeOliveira, D.B., Chan, I.C., Svendsen, J., Mariuzza, R.A., Stern, L.J.
Deposit date:2003-07-09
Release date:2003-12-09
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Exploration of the P6/P7 region of the peptide-binding site of the human class II Major Histocompatability Complex Protein HLA-DR1
J.Biol.Chem., 278, 2003
1R1P
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STRUCTURAL BASIS FOR DIFFERENTIAL RECOGNITION OF TYROSINE PHOSPHORYLATED SITES IN THE LINKER FOR ACTIVATION OF T CELLS (LAT) BY THE ADAPTOR PROTEIN GADS
Descriptor:GRB2-related adaptor protein 2, LAT pY171 peptide, SULFATE ION
Authors:Cho, S., Mariuzza, R.A.
Deposit date:2003-09-24
Release date:2004-09-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads.
Embo J., 23, 2004
1R1Q
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STRUCTURAL BASIS FOR DIFFERENTIAL RECOGNITION OF TYROSINE PHOSPHORYLATED SITES IN THE LINKER FOR ACTIVATION OF T CELLS (LAT) BY THE ADAPTOR PROTEIN GADS
Descriptor:GRB2-related adaptor protein 2, LAT pY191 peptide, SULFATE ION
Authors:Cho, S., Mariuzza, R.A.
Deposit date:2003-09-24
Release date:2004-09-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads.
Embo J., 23, 2004
1R1S
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STRUCTURAL BASIS FOR DIFFERENTIAL RECOGNITION OF TYROSINE PHOSPHORYLATED SITES IN THE LINKER FOR ACTIVATION OF T CELLS (LAT) BY THE ADAPTOR PROTEIN GADS
Descriptor:GRB2-related adaptor protein 2, LAT pY226 peptide, SULFATE ION
Authors:Cho, S., Mariuzza, R.A.
Deposit date:2003-09-24
Release date:2004-09-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads.
Embo J., 23, 2004
1SBB
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T-CELL RECEPTOR BETA CHAIN COMPLEXED WITH SUPERANTIGEN SEB
Descriptor:PROTEIN (14.3.D T CELL ANTIGEN RECEPTOR), PROTEIN (STAPHYLOCOCCAL ENTEROTOXIN B)
Authors:Li, H., Mariuzza, R.A.
Deposit date:1999-02-22
Release date:1999-03-01
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structure of the complex between a T cell receptor beta chain and the superantigen staphylococcal enterotoxin B.
Immunity, 9, 1998
1SK3
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CRYSTAL STRUCTURE OF THE C-TERMINAL PEPTIDOGLYCAN-BINDING DOMAIN OF HUMAN PEPTIDOGLYCAN RECOGNITION PROTEIN IALPHA
Descriptor:Peptidoglycan recognition protein I-alpha, NICKEL (II) ION, SULFATE ION
Authors:Guan, R., Malchiodi, E.L., Qian, W., Schuck, P., Mariuzza, R.A.
Deposit date:2004-03-04
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ialpha
J.Biol.Chem., 279, 2004
1SK4
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CRYSTAL STRUCTURE OF THE C-TERMINAL PEPTIDOGLYCAN-BINDING DOMAIN OF HUMAN PEPTIDOGLYCAN RECOGNITION PROTEIN IALPHA
Descriptor:Peptidoglycan recognition protein I-alpha, SODIUM ION
Authors:Guan, R., Malchiodi, E.L., Qian, W., Schuck, P., Mariuzza, R.A.
Deposit date:2004-03-04
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ialpha
J.Biol.Chem., 279, 2004
1TWQ
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CRYSTAL STRUCTURE OF THE C-TERMINAL PGN-BINDING DOMAIN OF HUMAN PGRP-IALPHA IN COMPLEX WITH PGN ANALOG MURAMYL TRIPEPTIDE
Descriptor:peptidoglycan recognition protein-I-alpha, muramyl tripeptide, NICKEL (II) ION
Authors:Guan, R., Roychowdury, A., Boons, G.-A., Mariuzza, R.A.
Deposit date:2004-07-01
Release date:2004-12-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for peptidoglycan binding by peptidoglycan recognition proteins
Proc.Natl.Acad.Sci.USA, 101, 2004
1XGP
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STRUCTURE FOR ANTIBODY HYHEL-63 Y33A MUTANT COMPLEXED WITH HEN EGG LYSOZYME
Descriptor:antibody kappa light chain, antibody kappa heavy chain, Lysozyme C
Authors:Li, Y., Mariuzza, R.A.
Deposit date:2004-09-17
Release date:2005-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
Structure, 13, 2005
1XGQ
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STRUCTURE FOR ANTIBODY HYHEL-63 Y33V MUTANT COMPLEXED WITH HEN EGG LYSOZYME
Descriptor:antibody kappa light chain, antibody kappa heavy chain, Lysozyme C
Authors:Li, Y., Mariuzza, R.A.
Deposit date:2004-09-17
Release date:2005-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
Structure, 13, 2005
1XGR
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STRUCTURE FOR ANTIBODY HYHEL-63 Y33I MUTANT COMPLEXED WITH HEN EGG LYSOZYME
Descriptor:antibody kappa light chain, antibody kappa heavy chain, Lysozyme C
Authors:Li, Y., Huang, Y., Swaminathan, C.P., Smith-Gill, S.J., Mariuzza, R.A.
Deposit date:2004-09-17
Release date:2005-09-06
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
Structure, 13, 2005
1XGT
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STRUCTURE FOR ANTIBODY HYHEL-63 Y33L MUTANT COMPLEXED WITH HEN EGG LYSOZYME
Descriptor:antibody kappa light chain, antibody kappa heavy chain, Lysozyme C
Authors:Li, Y., Mariuzza, R.A.
Deposit date:2004-09-17
Release date:2005-09-06
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
Structure, 13, 2005