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6DG5
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STRUCTURE OF A DE NOVO DESIGNED INTERLEUKIN-2/INTERLEUKIN-15 MIMETIC COMPLEX WITH IL-2RB AND IL-2RG
Descriptor:Neoleukin-2/15, Interleukin-2 receptor subunit beta, Cytokine receptor common subunit gamma, ...
Authors:Jude, K.M., Silva, D.-A., Yu, S., Baker, D., Garcia, K.C.
Deposit date:2018-05-16
Release date:2019-01-16
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.516 Å)
Cite:De novo design of potent and selective mimics of IL-2 and IL-15.
Nature, 565, 2019
6DG6
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STRUCTURE OF A DE NOVO DESIGNED INTERLEUKIN-2/INTERLEUKIN-15 MIMETIC
Descriptor:Neoleukin-2/15
Authors:Jude, K.M., Silva, D.-A., Yu, S., Baker, D., Garcia, K.C.
Deposit date:2018-05-16
Release date:2019-01-16
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:De novo design of potent and selective mimics of IL-2 and IL-15.
Nature, 565, 2019
6E5C
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SOLUTION NMR STRUCTURE OF A DE NOVO DESIGNED DOUBLE-STRANDED BETA-HELIX
Descriptor:De novo beta protein
Authors:Marcos, E., Chidyausiku, T.M., McShan, A., Evangelidis, T., Nerli, S., Sgourakis, N., Tripsianes, K., Baker, D.
Deposit date:2018-07-19
Release date:2018-11-07
Last modified:2018-11-14
Method:SOLUTION NMR
Cite:De novo design of a non-local beta-sheet protein with high stability and accuracy.
Nat. Struct. Mol. Biol., 25, 2018
6E9R
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DHF46 FILAMENT
Descriptor:DHF46 filament
Authors:Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D.
Deposit date:2018-08-01
Release date:2018-11-21
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:De novo design of self-assembling helical protein filaments.
Science, 362, 2018
6E9T
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DHF58 FILAMENT
Descriptor:DHF58 filament
Authors:Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D.
Deposit date:2018-08-01
Release date:2018-11-21
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:De novo design of self-assembling helical protein filaments.
Science, 362, 2018
6E9V
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DHF79 FILAMENT
Descriptor:DHF79 filament
Authors:Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D.
Deposit date:2018-08-01
Release date:2018-11-21
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:De novo design of self-assembling helical protein filaments.
Science, 362, 2018
6E9X
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DHF91 FILAMENT
Descriptor:DHF91 filament
Authors:Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D.
Deposit date:2018-08-01
Release date:2018-11-21
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:De novo design of self-assembling helical protein filaments.
Science, 362, 2018
6E9Y
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DHF38 FILAMENT
Descriptor:DHF38 filament
Authors:Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D.
Deposit date:2018-08-01
Release date:2018-11-21
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:De novo design of self-assembling helical protein filaments.
Science, 362, 2018
6E9Z
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DHF119 FILAMENT
Descriptor:DHF119 filament
Authors:Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D.
Deposit date:2018-08-01
Release date:2018-11-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:De novo design of self-assembling helical protein filaments.
Science, 362, 2018
6MRR
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DE NOVO DESIGNED PROTEIN FOLDIT1
Descriptor:Foldit1
Authors:Koepnick, B., Bick, M.J., Estep, R.D., Kleinfelter, S., Wei, L., Baker, D.
Deposit date:2018-10-15
Release date:2019-06-12
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:De novo protein design by citizen scientists.
Nature, 570, 2019
6MRS
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DE NOVO DESIGNED PROTEIN PEAK6
Descriptor:Peak6, SULFATE ION
Authors:Koepnick, B., Boykov, A., Baker, D.
Deposit date:2018-10-15
Release date:2019-06-12
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.541 Å)
Cite:De novo protein design by citizen scientists.
Nature, 570, 2019
6MSP
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DE NOVO DESIGNED PROTEIN FOLDIT3
Descriptor:De novo Designed Protein Foldit3
Authors:Liu, G., Ishida, Y., Swapna, G.V.T., Kleinfelter, S., Koepnick, B., Baker, D., Montelione, G.T.
Deposit date:2018-10-17
Release date:2019-06-12
Last modified:2019-07-03
Method:SOLUTION NMR
Cite:De novo protein design by citizen scientists.
Nature, 570, 2019
6MSQ
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CRYSTAL STRUCTURE OF PRO-2.3
Descriptor:pRO-2.3
Authors:Boyken, S.E., Sankaran, B., Bick, M.J., Baker, D.
Deposit date:2018-10-17
Release date:2019-05-08
Last modified:2020-03-18
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:De novo design of tunable, pH-driven conformational changes.
Science, 364, 2019
6MSR
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CRYSTAL STRUCTURE OF PRO-2.5
Descriptor:pRO-2.5
Authors:Bick, M.J., Sankaran, B., Boyken, S.E., Baker, D.
Deposit date:2018-10-17
Release date:2019-05-08
Last modified:2020-03-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:De novo design of tunable, pH-driven conformational changes.
Science, 364, 2019
6N9H
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DE NOVO DESIGNED HOMO-TRIMERIC AMANTADINE-BINDING PROTEIN
Descriptor:amantadine-binding protein, (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, SODIUM ION
Authors:Park, J., Baker, D.
Deposit date:2018-12-03
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.039 Å)
Cite:De novo design of a homo-trimeric amantadine-binding protein.
Elife, 8, 2019
6NAF
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DE NOVO DESIGNED HOMO-TRIMERIC AMANTADINE-BINDING PROTEIN
Descriptor:amantadine-binding protein, (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, SODIUM ION
Authors:Selvaraj, B., Park, J., Cuneo, M.J., Myles, D.A.A., Baker, D.
Deposit date:2018-12-05
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.923 Å), NEUTRON DIFFRACTION
Cite:De novo design of a homo-trimeric amantadine-binding protein.
Elife, 8, 2019
6NUK
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DE NOVO DESIGNED PROTEIN FERREDOG-DIESEL
Descriptor:Ferredog-Diesel
Authors:Koepnick, B., Bick, M.J., DiMaio, F., Norgard-Solano, T., Baker, D.
Deposit date:2019-02-01
Release date:2019-06-12
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:De novo protein design by citizen scientists.
Nature, 570, 2019
6W2Q
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JUNCTION 34, DHR53-DHR4
Descriptor:Junction 34, CALCIUM ION
Authors:Bick, M.J., Brunette, T.J., Baker, D.
Deposit date:2020-03-08
Release date:2020-04-15
Last modified:2020-04-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W2R
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JUNCTION 19, DHR54-DHR79
Descriptor:Junction 19 DHR54-DHR79
Authors:Bick, M.J., Brunette, T.J., Baker, D.
Deposit date:2020-03-08
Release date:2020-04-15
Last modified:2020-04-29
Method:X-RAY DIFFRACTION (2.344 Å)
Cite:Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W2V
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JUNCTION 23, DHR14-DHR18
Descriptor:Junction 23 DHR14-DHR18
Authors:Bick, M.J., Brunette, T.J., Baker, D.
Deposit date:2020-03-08
Release date:2020-04-15
Last modified:2020-04-29
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W2W
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JUNCTION 24, DHR14-DHR18
Descriptor:Junction 24 DHR14-DHR18
Authors:Bick, M.J., Brunette, T.J., Baker, D.
Deposit date:2020-03-08
Release date:2020-04-15
Last modified:2020-04-29
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W3D
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RD1NTF2_05 WITH LONG SHEET
Descriptor:Rd1NTF2_05
Authors:Bick, M.J., Basanta, B., Baker, D.
Deposit date:2020-03-09
Release date:2020-04-15
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:A generative algorithm for de novo design of proteins with diverse pockets
To Be Published
6W3F
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RD1NTF2_05_I64F_A80G_T94P_D101K_L106W
Descriptor:Rd1NTF2_05_I64F_A80G_T94P_D101K_L106W
Authors:Bick, M.J., Basanta, B., Baker, D.
Deposit date:2020-03-09
Release date:2020-04-15
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:A generative algorithm for de novo design of proteins with diverse pockets
To Be Published
6W3G
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RD1NTF2_04 WITH LONG SHEET
Descriptor:Rd1NTF2_04
Authors:Bick, M.J., Basanta, B., Baker, D.
Deposit date:2020-03-09
Release date:2020-04-15
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:A generative algorithm for de novo design of proteins with diverse pockets
To Be Published
6W3W
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A GENERATIVE ALGORITHM FOR DE NOVO DESIGN OF PROTEINS WITH DIVERSE POCKETS
Descriptor:DENOVO NTF2, NITRATE ION
Authors:Bera, A.K., Basanta, B., Dimaio, F., Sankaran, B., Baker, D.
Deposit date:2020-03-09
Release date:2020-04-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A generative algorithm for de novo design of proteins with diverse pockets
To Be Published