6DG5 | | STRUCTURE OF A DE NOVO DESIGNED INTERLEUKIN-2/INTERLEUKIN-15 MIMETIC COMPLEX WITH IL-2RB AND IL-2RG | | Descriptor: | Neoleukin-2/15, Interleukin-2 receptor subunit beta, Cytokine receptor common subunit gamma, ... | | Authors: | Jude, K.M., Silva, D.-A., Yu, S., Baker, D., Garcia, K.C. | | Deposit date: | 2018-05-16 | | Release date: | 2019-01-16 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2.516 Å) | | Cite: | De novo design of potent and selective mimics of IL-2 and IL-15.
Nature, 565, 2019
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6DG6 | | STRUCTURE OF A DE NOVO DESIGNED INTERLEUKIN-2/INTERLEUKIN-15 MIMETIC | | Descriptor: | Neoleukin-2/15 | | Authors: | Jude, K.M., Silva, D.-A., Yu, S., Baker, D., Garcia, K.C. | | Deposit date: | 2018-05-16 | | Release date: | 2019-01-16 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (1.999 Å) | | Cite: | De novo design of potent and selective mimics of IL-2 and IL-15.
Nature, 565, 2019
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6E5C | | SOLUTION NMR STRUCTURE OF A DE NOVO DESIGNED DOUBLE-STRANDED BETA-HELIX | | Descriptor: | De novo beta protein | | Authors: | Marcos, E., Chidyausiku, T.M., McShan, A., Evangelidis, T., Nerli, S., Sgourakis, N., Tripsianes, K., Baker, D. | | Deposit date: | 2018-07-19 | | Release date: | 2018-11-07 | | Last modified: | 2018-11-14 | | Method: | SOLUTION NMR | | Cite: | De novo design of a non-local beta-sheet protein with high stability and accuracy.
Nat. Struct. Mol. Biol., 25, 2018
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6E9R | | DHF46 FILAMENT | | Descriptor: | DHF46 filament | | Authors: | Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D. | | Deposit date: | 2018-08-01 | | Release date: | 2018-11-21 | | Method: | ELECTRON MICROSCOPY (5.9 Å) | | Cite: | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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6E9T | | DHF58 FILAMENT | | Descriptor: | DHF58 filament | | Authors: | Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D. | | Deposit date: | 2018-08-01 | | Release date: | 2018-11-21 | | Method: | ELECTRON MICROSCOPY (5.4 Å) | | Cite: | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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6E9V | | DHF79 FILAMENT | | Descriptor: | DHF79 filament | | Authors: | Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D. | | Deposit date: | 2018-08-01 | | Release date: | 2018-11-21 | | Method: | ELECTRON MICROSCOPY (6.9 Å) | | Cite: | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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6E9X | | DHF91 FILAMENT | | Descriptor: | DHF91 filament | | Authors: | Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D. | | Deposit date: | 2018-08-01 | | Release date: | 2018-11-21 | | Method: | ELECTRON MICROSCOPY (7.8 Å) | | Cite: | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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6E9Y | | DHF38 FILAMENT | | Descriptor: | DHF38 filament | | Authors: | Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D. | | Deposit date: | 2018-08-01 | | Release date: | 2018-11-21 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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6E9Z | | DHF119 FILAMENT | | Descriptor: | DHF119 filament | | Authors: | Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D. | | Deposit date: | 2018-08-01 | | Release date: | 2018-11-21 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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6MRR | | DE NOVO DESIGNED PROTEIN FOLDIT1 | | Descriptor: | Foldit1 | | Authors: | Koepnick, B., Bick, M.J., Estep, R.D., Kleinfelter, S., Wei, L., Baker, D. | | Deposit date: | 2018-10-15 | | Release date: | 2019-06-12 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (1.18 Å) | | Cite: | De novo protein design by citizen scientists.
Nature, 570, 2019
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6MRS | |
6MSP | | DE NOVO DESIGNED PROTEIN FOLDIT3 | | Descriptor: | De novo Designed Protein Foldit3 | | Authors: | Liu, G., Ishida, Y., Swapna, G.V.T., Kleinfelter, S., Koepnick, B., Baker, D., Montelione, G.T. | | Deposit date: | 2018-10-17 | | Release date: | 2019-06-12 | | Last modified: | 2019-07-03 | | Method: | SOLUTION NMR | | Cite: | De novo protein design by citizen scientists.
Nature, 570, 2019
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6MSQ | | CRYSTAL STRUCTURE OF PRO-2.3 | | Descriptor: | pRO-2.3 | | Authors: | Boyken, S.E., Sankaran, B., Bick, M.J., Baker, D. | | Deposit date: | 2018-10-17 | | Release date: | 2019-05-08 | | Last modified: | 2020-03-18 | | Method: | X-RAY DIFFRACTION (1.28 Å) | | Cite: | De novo design of tunable, pH-driven conformational changes.
Science, 364, 2019
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6MSR | | CRYSTAL STRUCTURE OF PRO-2.5 | | Descriptor: | pRO-2.5 | | Authors: | Bick, M.J., Sankaran, B., Boyken, S.E., Baker, D. | | Deposit date: | 2018-10-17 | | Release date: | 2019-05-08 | | Last modified: | 2020-03-18 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | De novo design of tunable, pH-driven conformational changes.
Science, 364, 2019
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6N9H | | DE NOVO DESIGNED HOMO-TRIMERIC AMANTADINE-BINDING PROTEIN | | Descriptor: | amantadine-binding protein, (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, SODIUM ION | | Authors: | Park, J., Baker, D. | | Deposit date: | 2018-12-03 | | Release date: | 2019-12-18 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (1.039 Å) | | Cite: | De novo design of a homo-trimeric amantadine-binding protein.
Elife, 8, 2019
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6NAF | | DE NOVO DESIGNED HOMO-TRIMERIC AMANTADINE-BINDING PROTEIN | | Descriptor: | amantadine-binding protein, (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, SODIUM ION | | Authors: | Selvaraj, B., Park, J., Cuneo, M.J., Myles, D.A.A., Baker, D. | | Deposit date: | 2018-12-05 | | Release date: | 2019-12-18 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (1.923 Å), NEUTRON DIFFRACTION | | Cite: | De novo design of a homo-trimeric amantadine-binding protein.
Elife, 8, 2019
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6NUK | | DE NOVO DESIGNED PROTEIN FERREDOG-DIESEL | | Descriptor: | Ferredog-Diesel | | Authors: | Koepnick, B., Bick, M.J., DiMaio, F., Norgard-Solano, T., Baker, D. | | Deposit date: | 2019-02-01 | | Release date: | 2019-06-12 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | De novo protein design by citizen scientists.
Nature, 570, 2019
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6W2Q | | JUNCTION 34, DHR53-DHR4 | | Descriptor: | Junction 34, CALCIUM ION | | Authors: | Bick, M.J., Brunette, T.J., Baker, D. | | Deposit date: | 2020-03-08 | | Release date: | 2020-04-15 | | Last modified: | 2020-04-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6W2R | | JUNCTION 19, DHR54-DHR79 | | Descriptor: | Junction 19 DHR54-DHR79 | | Authors: | Bick, M.J., Brunette, T.J., Baker, D. | | Deposit date: | 2020-03-08 | | Release date: | 2020-04-15 | | Last modified: | 2020-04-29 | | Method: | X-RAY DIFFRACTION (2.344 Å) | | Cite: | Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6W2V | | JUNCTION 23, DHR14-DHR18 | | Descriptor: | Junction 23 DHR14-DHR18 | | Authors: | Bick, M.J., Brunette, T.J., Baker, D. | | Deposit date: | 2020-03-08 | | Release date: | 2020-04-15 | | Last modified: | 2020-04-29 | | Method: | X-RAY DIFFRACTION (2.399 Å) | | Cite: | Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6W2W | | JUNCTION 24, DHR14-DHR18 | | Descriptor: | Junction 24 DHR14-DHR18 | | Authors: | Bick, M.J., Brunette, T.J., Baker, D. | | Deposit date: | 2020-03-08 | | Release date: | 2020-04-15 | | Last modified: | 2020-04-29 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6W3D | |
6W3F | |
6W3G | |
6W3W | | A GENERATIVE ALGORITHM FOR DE NOVO DESIGN OF PROTEINS WITH DIVERSE POCKETS | | Descriptor: | DENOVO NTF2, NITRATE ION | | Authors: | Bera, A.K., Basanta, B., Dimaio, F., Sankaran, B., Baker, D. | | Deposit date: | 2020-03-09 | | Release date: | 2020-04-08 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | A generative algorithm for de novo design of proteins with diverse pockets
To Be Published
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