Author results

4AB5
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REGULATORY DOMAIN STRUCTURE OF NMB2055 (METR) A LYSR FAMILY REGULATOR FROM N. MENINGITIDIS
Descriptor:TRANSCRIPTIONAL REGULATOR, LYSR FAMILY
Authors:Sainsbury, S., Ren, J., Saunders, N.J., Stuart, D.I., Owens, R.J.
Deposit date:2011-12-07
Release date:2012-07-11
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of the Regulatory Domain of the Lysr Family Regulator Nmb2055 (Metr-Like Protein) from Neisseria Meningitidis
Acta Crystallogr.,Sect.F, 68, 2012
4AB6
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REGULATORY DOMAIN STRUCTURE OF NMB2055 (METR), C103S C106S MUTANT, A LYSR FAMILY REGULATOR FROM N. MENINGITIDIS
Descriptor:TRANSCRIPTIONAL REGULATOR, LYSR FAMILY, SULFATE ION
Authors:Sainsbury, S., Ren, J., Saunders, N.J., Stuart, D.I., Owens, R.J.
Deposit date:2011-12-07
Release date:2012-07-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Regulatory Domain of the Lysr Family Regulator Nmb2055 (Metr-Like Protein) from Neisseria Meningitidis
Acta Crystallogr.,Sect.F, 68, 2012
4B02
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THE C-TERMINAL PRIMING DOMAIN IS STRONGLY ASSOCIATED WITH THE MAIN BODY OF BACTERIOPHAGE PHI6 RNA-DEPENDENT RNA POLYMERASE
Descriptor:RNA-DIRECTED RNA POLYMERASE, MANGANESE (II) ION
Authors:Sarin, L.P., Wright, S., Chen, Q., Degerth, L.H., Stuart, D.I., Grimes, J.M., Bamford, D.H., Poranen, M.M.
Deposit date:2012-06-27
Release date:2012-08-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The C-Terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage Phi6 RNA-Dependent RNA Polymerase.
Virology, 432, 2012
4B7I
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CRYSTAL STRUCTURE OF HUMAN IGG FC BEARING HYBRID-TYPE GLYCANS
Descriptor:IG GAMMA-1 CHAIN C REGION, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Bowden, T.A., Baruah, K., Coles, C.H., Harvey, D.J., Song, B.D., Stuart, D.I., Aricescu, A.R., Scanlan, C.N., Jones, E.Y., Crispin, M.
Deposit date:2012-08-20
Release date:2012-10-17
Last modified:2012-11-07
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Chemical and Structural Analysis of an Antibody Folding Intermediate Trapped During Glycan Biosynthesis.
J.Am.Chem.Soc., 134, 2012
4BBB
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THE STRUCTURE OF VACCINIA VIRUS N1 Q61Y MUTANT
Descriptor:N1L
Authors:Maluquer de Motes, C., Cooray, S., McGourty, K., Ren, H., Bahar, M.W., Stuart, D.I., Grimes, J.M., Graham, S.C., Smith, G.L.
Deposit date:2012-09-21
Release date:2012-10-03
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Inhibition of Apoptosis and NF-kappaB Activation by Vaccinia Protein N1 Occur Via Distinct Binding Surfaces and Make Different Contributions to Virulence.
Plos Pathog., 7, 2011
4BBC
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THE STRUCTURE OF VACCINIA VIRUS N1 R71Y MUTANT
Descriptor:N1L
Authors:Maluquer de Motes, C., Cooray, S., McGourty, K., Ren, H., Bahar, M.W., Stuart, D.I., Grimes, J.M., Graham, S.C., Smith, G.L.
Deposit date:2012-09-21
Release date:2012-10-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Inhibition of Apoptosis and NF-kappaB Activation by Vaccinia Protein N1 Occur Via Distinct Binding Surfaces and Make Different Contributions to Virulence.
Plos Pathog., 7, 2011
4BBD
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THE STRUCTURE OF VACCINIA VIRUS N1 R58Y MUTANT
Descriptor:N1L
Authors:Maluquer de Motes, C., Cooray, S., McGourty, K., Ren, H., Bahar, M.W., Stuart, D.I., Grimes, J.M., Graham, S.C., Smith, G.L.
Deposit date:2012-09-21
Release date:2012-10-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Inhibition of Apoptosis and NF-kappaB Activation by Vaccinia Protein N1 Occur Via Distinct Binding Surfaces and Make Different Contributions to Virulence.
Plos Pathog., 7, 2011
4BLO
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P4 PROTEIN FROM BACTERIOPHAGE PHI6 IN COMPLEX WITH ADP
Descriptor:PACKAGING ENZYME P4, CALCIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:El Omari, K., Meier, C., Kainov, D., Sutton, G., Grimes, J.M., Poranen, M.M., Bamford, D.H., Tuma, R., Stuart, D.I., Mancini, E.J.
Deposit date:2013-05-04
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution.
Nucleic Acids Res., 41, 2013
4BLP
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P4 PROTEIN FROM BACTERIOPHAGE PHI13
Descriptor:PACKAGING ENZYME P4, CITRATE ANION, GLYCEROL
Authors:El Omari, K., Meier, C., Kainov, D., Sutton, G., Grimes, J.M., Poranen, M.M., Bamford, D.H., Tuma, R., Stuart, D.I., Mancini, E.J.
Deposit date:2013-05-04
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution.
Nucleic Acids Res., 41, 2013
4BLQ
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P4 PROTEIN FROM BACTERIOPHAGE PHI8
Descriptor:P4
Authors:El Omari, K., Meier, C., Kainov, D., Sutton, G., Grimes, J.M., Poranen, M.M., Bamford, D.H., Tuma, R., Stuart, D.I., Mancini, E.J.
Deposit date:2013-05-04
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution.
Nucleic Acids Res., 41, 2013
4BLR
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P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH UTP
Descriptor:NTPASE P4, URIDINE 5'-TRIPHOSPHATE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE
Authors:El Omari, K., Meier, C., Kainov, D., Sutton, G., Grimes, J.M., Poranen, M.M., Bamford, D.H., Tuma, R., Stuart, D.I., Mancini, E.J.
Deposit date:2013-05-04
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution.
Nucleic Acids Res., 41, 2013
4BLS
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P4 PROTEIN FROM BACTERIOPHAGE PHI12 Q278A MUTANT IN COMPLEX WITH AMPCPP
Descriptor:NTPASE P4, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER
Authors:El Omari, K., Meier, C., Kainov, D., Sutton, G., Grimes, J.M., Poranen, M.M., Bamford, D.H., Tuma, R., Stuart, D.I., Mancini, E.J.
Deposit date:2013-05-04
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution.
Nucleic Acids Res., 41, 2013
4BLT
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P4 PROTEIN FROM BACTERIOPHAGE PHI12 S292A MUTANT IN COMPLEX WITH AMPCPP
Descriptor:NTPASE P4, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER
Authors:El Omari, K., Meier, C., Kainov, D., Sutton, G., Grimes, J.M., Poranen, M.M., Bamford, D.H., Tuma, R., Stuart, D.I., Mancini, E.J.
Deposit date:2013-05-04
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution.
Nucleic Acids Res., 41, 2013
4BTP
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STRUCTURE OF THE CAPSID PROTEIN P1 OF THE BACTERIOPHAGE PHI8
Descriptor:p1
Authors:El Omari, K., Sutton, G., Ravantti, J.J., Zhang, H., Walter, T.S., Grimes, J.M., Bamford, D.H., Stuart, D.I., Mancini, E.J.
Deposit date:2013-06-18
Release date:2013-08-07
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Plate Tectonics of Virus Shell Assembly and Reorganization in Phage Phi8, a Distant Relative of Mammalian Reoviruses
Structure, 21, 2013
4BWY
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P4 PROTEIN FROM BACTERIOPHAGE PHI8 (R32)
Descriptor:P4
Authors:El Omari, K., Meier, C., Kainov, D., Sutton, G., Grimes, J.M., Poranen, M.M., Bamford, D.H., Tuma, R., Stuart, D.I., Mancini, E.J.
Deposit date:2013-07-05
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution.
Nucleic Acids Res., 41, 2013
4BX4
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FITTING OF THE BACTERIOPHAGE PHI8 P1 CAPSID PROTEIN INTO CRYO-EM DENSITY
Descriptor:P1
Authors:El Omari, K., Sutton, G., Ravantti, J.J., Zhang, H., Walter, T.S., Grimes, J.M., Bamford, D.H., Stuart, D.I., Mancini, E.J.
Deposit date:2013-07-08
Release date:2013-08-07
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Plate Tectonics of Virus Shell Assembly and Reorganization in Phage Phi8, a Distant Relative of Mammalian Reoviruses
Structure, 21, 2013
4FJV
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CRYSTAL STRUCTURE OF HUMAN OTUBAIN2 AND UBIQUITIN COMPLEX
Descriptor:Ubiquitin thioesterase OTUB2, Polyubiquitin-C, GLYCEROL, ...
Authors:Altun, M., Walter, T.S., Kramer, H.B., Iphofer, A., David, Y., Komsany, A., Ternette, N., Nicholson, B., Navon, A., Stuart, D.I., Ren, J., Kessler, B.M.
Deposit date:2012-06-12
Release date:2013-06-12
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.
Plos One, 10, 2015
4I2X
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CRYSTAL STRUCTURE OF SIGNAL REGULATORY PROTEIN GAMMA (SIRP-GAMMA) IN COMPLEX WITH FABOX117
Descriptor:FabOX117 light chain, FabOX117 heavy chain, Signal-regulatory protein gamma, ...
Authors:Nettleship, J.E., Ren, J., Stuart, D.I., Owens, R.J., Oxford Protein Production Facility (OPPF)
Deposit date:2012-11-23
Release date:2013-12-18
Last modified:2014-12-24
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Crystal structure of signal regulatory protein gamma (SIRP gamma) in complex with an antibody Fab fragment.
Bmc Struct.Biol., 13, 2013
4IV1
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CRYSTAL STRUCTURE OF RECOMBINANT FOOT-AND-MOUTH-DISEASE VIRUS A22 EMPTY CAPSID
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Porta, C., Kotecha, A., Burman, A., Jackson, T., Ren, J., Loureiro, S., Jones, I.M., Fry, E.E., Stuart, D.I., Charleston, B.
Deposit date:2013-01-22
Release date:2013-04-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.
Plos Pathog., 9, 2013
4IV3
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CRYSTAL STRUCTURE OF RECOMBINANT FOOT-AND-MOUTH-DISEASE VIRUS A22-H2093C EMPTY CAPSID
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Porta, C., Kotecha, A., Burman, A., Jackson, T., Ren, J., Loureiro, S., Jones, I.M., Fry, E.E., Stuart, D.I., Charleston, B.
Deposit date:2013-01-22
Release date:2013-04-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.
Plos Pathog., 9, 2013
4JGY
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CRYSTAL STRUCTURE OF HUMAN COXSACKIEVIRUS A16 UNCOATING INTERMEDIATE (SPACE GROUP P4232)
Descriptor:Polyprotein, capsid protein VP1, capsid protein VP2, ...
Authors:Ren, J., Wang, X., Hu, Z., Gao, Q., Sun, Y., Li, X., Porta, C., Walter, T.S., Gilbert, R.J., Zhao, Y., Axford, D., Williams, M., Mcauley, K., Rowlands, D.J., Yin, W., Wang, J., Stuart, D.I., Rao, Z., Fry, E.E.
Deposit date:2013-03-04
Release date:2013-06-05
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Picornavirus uncoating intermediate captured in atomic detail.
Nat Commun, 4, 2013
4JGZ
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CRYSTAL STRUCTURE OF HUMAN COXSACKIEVIRUS A16 UNCOATING INTERMEDIATE (SPACE GROUP I222)
Descriptor:Polyprotein, capsid protein VP1, capsid protein VP2, ...
Authors:Ren, J., Wang, X., Hu, Z., Gao, Q., Sun, Y., Li, X., Porta, C., Walter, T.S., Gilbert, R.J., Zhao, Y., Axford, D., Williams, M., McAuley, K., Rowlands, D.J., Yin, W., Wang, J., Stuart, D.I., Rao, Z., Fry, E.E.
Deposit date:2013-03-04
Release date:2013-06-05
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Picornavirus uncoating intermediate captured in atomic detail.
Nat Commun, 4, 2013
4KQO
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CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH PIPERACILLIN
Descriptor:Penicillin-binding protein 3, Piperacillin (Open Form), GLYCEROL, ...
Authors:Nettleship, J.E., Stuart, D.I., Owens, R.J., Ren, J.
Deposit date:2013-05-15
Release date:2013-11-06
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3.
Acs Chem.Biol., 8, 2013
4KQQ
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CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH (5S)-PENICILLOIC ACID
Descriptor:Penicillin-binding protein 3, (2S,4S)-2-[(R)-carboxy{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, ...
Authors:Nettleship, J.E., Stuart, D.I., Owens, R.J., Ren, J.
Deposit date:2013-05-15
Release date:2013-11-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3.
Acs Chem.Biol., 8, 2013
4KQR
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CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH (5S)-PENICILLOIC ACID
Descriptor:Penicillin-binding protein 3, (2S,4S)-2-[(R)-carboxy{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, ...
Authors:Nettleship, J.E., Stuart, D.I., Owens, R.J., Ren, J.
Deposit date:2013-05-15
Release date:2013-11-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3.
Acs Chem.Biol., 8, 2013