7Z3Z

Locked Wuhan SARS-CoV2 Prefusion Spike ectodomain with lipid bound

Summary for 7Z3Z

• Entry DOI: 10.2210/pdb7z3z/pdb
• Related: 6Z97
• EMDB information: 11119 14481
• Descriptor: Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: spike, sars-cov2, lipid, locked-in, conformation, covid19, rbd-down, therapeutics, vaccine, closed, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 3
• Total formula weight: 442408.25

Authors

Duyvesteyn, H.M.E.,Carrique, L.,Ren, J.,Stuart, D.I.,Fry, E.E. (deposition date: 2022-03-03, release date: 2022-05-04)

• Primary citation: Duyvesteyn, H.M.E.,Carrique, L.,Ren, J.,Stuart, D.I.,Fry, E.E.,Zhao, Y.,Malinauskas, T.,Zhou, D.; The SARS-CoV-2 Spike harbours a lipid binding pocket which modulates stability of the prefusion trimer; bioRxiv, 2020; DOI: 10.1101/2020.08.13.249177

Experimental method

ELECTRON MICROSCOPY (3.1 Å)