Author results

5DLJ
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CRYSTAL STRUCTURE OF CAS-DNA-N1 COMPLEX
分子名称:CRISPR-associated endonuclease Cas1, 39-mer DNA N1-F, 39-mer DNA N1-R, ...
著者Wang, J., Li, J., Zhao, H., Sheng, G., Wang, M., Yin, M., Wang, Y.
登録日2015-09-05
公開日2015-11-11
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
5DQT
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CRYSTAL STRUCTURE OF CAS-DNA-22 COMPLEX
分子名称:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (34-MER), ...
著者Wang, J., Li, J., Zhao, H., Sheng, G., Wang, M., Yin, M., Wang, Y.
登録日2015-09-15
公開日2015-11-11
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
5DQU
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CRYSTAL STRUCTURE OF CAS-DNA-10 COMPLEX
分子名称:CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (5'-D(*GP*AP*GP*TP*CP*GP*AP*TP*GP*CP*TP*TP*TP*TP*T)-3'), ...
著者Wang, J., Li, J., Zhao, H., Sheng, G., Wang, M., Yin, M., Wang, Y.
登録日2015-09-15
公開日2015-11-11
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
5DQZ
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CRYSTAL STRUCTURE OF CAS-DNA-PAM COMPLEX
分子名称:CRISPR-associated endonuclease Cas1, DNA (36-MER), CRISPR-associated endoribonuclease Cas2, ...
著者Wang, J., Li, J., Zhao, H., Sheng, G., Wang, M., Yin, M., Wang, Y.
登録日2015-09-15
公開日2015-11-11
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
5XAF
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-COMPOUND Z1 COMPLEX
分子名称:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
著者Zhang, H., Luo, C., Wang, Y.
登録日2017-03-12
公開日2017-12-20
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.551 Å)
主引用文献Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents
Eur J Med Chem, 144, 2017
5XAG
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-COMPOUND Z2 COMPLEX
分子名称:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
著者Zhang, H., Luo, C., Wang, Y.
登録日2017-03-12
公開日2018-01-03
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents
Eur J Med Chem, 144, 2017
5XWY
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ELECTRON CRYO-MICROSCOPY STRUCTURE OF LBUCAS13A-CRRNA BINARY COMPLEX
分子名称:A type VI-A CRISPR-Cas RNA-guided RNA ribonuclease, Cas13a, RNA (59-MER)
著者Zhang, X., Wang, Y., Ma, J., Liu, L., Li, X., Li, Z., You, L., Wang, J., Wang, M.
登録日2017-06-30
公開日2017-09-13
最終更新日2018-10-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a.
Cell, 170, 2017
5YEF
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CRYSTAL STRUCTURE OF CTCF ZFS2-8-HS5-1AE
分子名称:Transcriptional repressor CTCF, DNA (27-MER), ZINC ION
著者Yin, M., Wang, J., Wang, M., Li, X., Wang, Y.
登録日2017-09-17
公開日2017-11-29
実験手法X-RAY DIFFRACTION (2.807 Å)
主引用文献Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites
Cell Res., 27, 2017
5YEH
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CRYSTAL STRUCTURE OF CTCF ZFS4-8-ECBS
分子名称:Transcriptional repressor CTCF, DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*CP*CP*GP*CP*TP*AP*GP*AP*GP*GP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*AP*GP*CP*GP*GP*AP*AP*AP*CP*CP*G)-3'), ...
著者Yin, M., Wang, J., Wang, M., Li, X., Wang, Y.
登録日2017-09-17
公開日2017-11-29
最終更新日2019-01-23
実験手法X-RAY DIFFRACTION (2.328 Å)
主引用文献Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites
Cell Res., 27, 2017
5YEL
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CRYSTAL STRUCTURE OF CTCF ZFS6-11-GB7CSE
分子名称:DNA (26-MER), Transcriptional repressor CTCF, ZINC ION
著者Yin, M., Wang, J., Wang, M., Li, X., Wang, Y.
登録日2017-09-18
公開日2017-11-29
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites
Cell Res., 27, 2017
5Z10
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STRUCTURE OF THE MECHANOSENSITIVE PIEZO1 CHANNEL
分子名称:Piezo-type mechanosensitive ion channel component 1
著者Zhao, Q., Zhou, H., Chi, S., Wang, Y., Wang, J., Geng, J., Wu, K., Liu, W., Zhang, T., Dong, M.-Q., Wang, J., Li, X., Xiao, B.
登録日2017-12-22
公開日2018-01-31
最終更新日2018-03-07
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献Structure and mechanogating mechanism of the Piezo1 channel.
Nature, 554, 2018
5GNF
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CRYSTAL STRUCTURE OF ANTI-CRISPR PROTEIN ACRF3
分子名称:Uncharacterized protein AcrF3, CALCIUM ION
著者Wang, J., Wang, Y.
登録日2016-07-20
公開日2016-09-21
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
5GQH
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CRYO-EM STRUCTURE OF PAECAS3-ACRF3 COMPLEX
分子名称:CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST, anti-CRISPR protein 3
著者Zhang, X., Ma, J., Wang, Y., Wang, J.
登録日2016-08-07
公開日2016-09-21
最終更新日2016-10-19
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
6IFK
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CRYO-EM STRUCTURE OF TYPE III-A CSM-CTR1 COMPLEX, AMPPNP BOUND
分子名称:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
著者You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
登録日2018-09-20
公開日2018-12-12
最終更新日2019-01-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFL
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CRYO-EM STRUCTURE OF TYPE III-A CSM-NTR COMPLEX
分子名称:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
著者You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
登録日2018-09-20
公開日2018-12-12
最終更新日2019-01-23
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFN
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CRYSTAL STRUCTURE OF TYPE III-A CRISPR CSM COMPLEX
分子名称:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ...
著者You, L., Wang, J., Wang, Y.
登録日2018-09-20
公開日2018-12-12
最終更新日2019-01-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFR
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-NTR, ATP BOUND
分子名称:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
著者You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
登録日2018-09-21
公開日2018-12-12
最終更新日2019-01-23
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFU
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CRYO-EM STRUCTURE OF TYPE III-A CSM-CTR2-DSDNA COMPLEX
分子名称:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
著者You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
登録日2018-09-21
公開日2018-12-12
最終更新日2019-05-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFY
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-CTR1
分子名称:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
著者You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
登録日2018-09-21
公開日2018-12-12
最終更新日2019-01-23
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFZ
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-CTR2-SSDNA COMPLEX
分子名称:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
著者You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
登録日2018-09-21
公開日2018-12-12
最終更新日2019-01-23
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IG0
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-CTR1, ATP BOUND
分子名称:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
著者You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
登録日2018-09-21
公開日2018-12-12
最終更新日2019-01-23
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
1R7J
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CRYSTAL STRUCTURE OF THE DNA-BINDING PROTEIN SSO10A FROM SULFOLOBUS SOLFATARICUS
分子名称:Conserved hypothetical protein Sso10a
著者Chen, L., Chen, L.R., Zhou, X.E., Wang, Y., Kahsai, M.A., Clark, A.T., Edmondson, S.P., Liu, Z.-J., Rose, J.P., Wang, B.C., Shriver, J.W., Meehan, E.J., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2003-10-21
公開日2004-07-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献The hyperthermophile protein Sso10a is a dimer of winged helix DNA-binding domains linked by an antiparallel coiled coil rod.
J.Mol.Biol., 341, 2004
2KLJ
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SOLUTION STRUCTURE OF GAMMAD-CRYSTALLIN WITH RDC AND SAXS
分子名称:Gamma-crystallin D
著者Wang, J., Zuo, X., Yu, P., Byeon, I., Jung, J., Gronenborn, A.M., Wang, Y.
登録日2009-07-06
公開日2009-10-06
最終更新日2011-07-13
実験手法SOLUTION SCATTERING, SOLUTION NMR
主引用文献Determination of multicomponent protein structures in solution using global orientation and shape restraints.
J.Am.Chem.Soc., 131, 2009
2KLM
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SOLUTION STRUCTURE OF L11 WITH SAXS AND RDC
分子名称:50S ribosomal protein L11
著者Wang, J., Zuo, X., Yu, P., Schwieters, C.D., Wang, Y.
登録日2009-07-06
公開日2009-10-06
最終更新日2011-07-13
実験手法SOLUTION SCATTERING, SOLUTION NMR
主引用文献Determination of multicomponent protein structures in solution using global orientation and shape restraints.
J.Am.Chem.Soc., 131, 2009
2YJY
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A SPECIFIC AND MODULAR BINDING CODE FOR CYTOSINE RECOGNITION IN PUF DOMAINS
分子名称:PUMILIO HOMOLOG 1, 5'-R(*AP*UP*UP*GP*CP*AP*UP*AP*UP*AP)-3'
著者Dong, S., Wang, Y., Cassidy-Amstutz, C., Lu, G., Qiu, C., Bigler, R., Jezyk, M., Li, C., Hall, T.M.T., Wang, Z.
登録日2011-05-24
公開日2011-06-08
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献Specific and Modular Binding Code for Cytosine Recognition in Pumilio/Fbf (Puf) RNA-Binding Domains.
J.Biol.Chem., 286, 2011