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1BZQ
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BU of 1bzq by Molmil
COMPLEX OF A DROMEDARY SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A
Descriptor: PHOSPHATE ION, PROTEIN (ANTIBODY CAB-RN05), PROTEIN (RNASE A)
Authors:Decanniere, K, Desmyter, A, Gahroudhi, M, Lauwereys, M, Muyldermans, S, Wyns, L.
Deposit date:1998-11-03
Release date:1998-11-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops.
Structure Fold.Des., 7, 1999
5M7Q
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BU of 5m7q by Molmil
Engineering the Thermostability of Nanobodies - NbD2
Descriptor: CHLORIDE ION, MAGNESIUM ION, Nanobody NbD2, ...
Authors:Soler, N, Kunz, P, Muyldermans, S.
Deposit date:2016-10-28
Release date:2016-11-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Engineering the Thermostability of Nanobodies
To be published
6FE4
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BU of 6fe4 by Molmil
Crystal structure of the complex between Shiga toxin Stx2 B subunit and neutralising Nb113
Descriptor: Nb113, Shiga-like toxin 2 subunit B
Authors:Bernedo, R, Muyldermans, S, Sterckx, Y.G.J.
Deposit date:2017-12-29
Release date:2018-03-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for the Specific Neutralization of Stx2a with a Camelid Single Domain Antibody Fragment.
Toxins (Basel), 10, 2018
5F8R
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BU of 5f8r by Molmil
Blood group antigen binding adhesin BabA of Helicobacter pylori strain S831 in complex with blood group H Lewis b hexasaccharide
Descriptor: Adhesin binding fucosylated histo-blood group antigen,Adhesin,Adhesin binding fucosylated histo-blood group antigen, Nanobody Nb-ER19, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Moonens, K, Gideonsson, P, Subedi, S, Romao, E, Oscarson, S, Muyldermans, S, Boren, T, Remaut, H.
Deposit date:2015-12-09
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.
Cell Host Microbe, 19, 2016
5F93
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BU of 5f93 by Molmil
Blood group antigen binding adhesin BabA of Helicobacter pylori strain A730 in complex with blood group H Lewis b hexasaccharide
Descriptor: Adhesin binding fucosylated histo-blood group antigen,Adhesin,Adhesin binding fucosylated histo-blood group antigen, Nanobody Nb-ER19, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
Authors:Moonens, K, Gideonsson, P, Subedi, S, Romao, E, Oscarson, S, Muyldermans, S, Boren, T, Remaut, H.
Deposit date:2015-12-09
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.
Cell Host Microbe, 19, 2016
5F7M
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BU of 5f7m by Molmil
Blood group antigen binding adhesin BabA of Helicobacter pylori strain 17875 in complex with blood group H Lewis b hexasaccharide
Descriptor: Adhesin binding fucosylated histo-blood group antigen, Nanobody Nb-ER19, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Moonens, K, Gideonsson, P, Subedi, S, Romao, E, Oscarson, S, Muyldermans, S, Boren, T, Remaut, H.
Deposit date:2015-12-08
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.
Cell Host Microbe, 19, 2016
5F8Q
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BU of 5f8q by Molmil
Blood group antigen binding adhesin BabA of Helicobacter pylori strain S831 in complex with Nanobody Nb-ER19
Descriptor: Adhesin binding fucosylated histo-blood group antigen,Adhesin,Adhesin binding fucosylated histo-blood group antigen, Nanobody Nb-ER19
Authors:Moonens, K, Gideonsson, P, Subedi, S, Romao, E, Oscarson, S, Muyldermans, S, Boren, T, Remaut, H.
Deposit date:2015-12-09
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.
Cell Host Microbe, 19, 2016
5F9D
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BU of 5f9d by Molmil
Blood group antigen binding adhesin BabA of Helicobacter pylori strain P436 in complex with Lewis b blood group B heptasaccharide
Descriptor: Adhesin binding fucosylated histo-blood group antigen,Adhesin,Adhesin binding fucosylated histo-blood group antigen, Nanobody Nb-ER19, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Moonens, K, Gideonsson, P, Subedi, S, Romao, E, Oscarson, S, Muyldermans, S, Boren, T, Remaut, H.
Deposit date:2015-12-09
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.
Cell Host Microbe, 19, 2016
5F7W
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BU of 5f7w by Molmil
Blood group antigen binding adhesin BabA of Helicobacter pylori strain 17875 in complex with blood group B Lewis b heptasaccharide
Descriptor: Adhesin binding fucosylated histo-blood group antigen, Nanobody Nb-ER19, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Moonens, K, Gideonsson, P, Subedi, S, Romao, E, Oscarson, S, Muyldermans, S, Boren, T, Remaut, H.
Deposit date:2015-12-08
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.
Cell Host Microbe, 19, 2016
5F7N
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BU of 5f7n by Molmil
Blood group antigen binding adhesin BabA of Helicobacter pylori strain 17875 in complex with blood group A Lewis b pentasaccharide
Descriptor: Adhesin binding fucosylated histo-blood group antigen, Nanobody Nb-ER19, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Moonens, K, Gideonsson, P, Subedi, S, Romao, E, Oscarson, S, Muyldermans, S, Boren, T, Remaut, H.
Deposit date:2015-12-08
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.
Cell Host Microbe, 19, 2016
5FOJ
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BU of 5foj by Molmil
Cryo electron microscopy structure of Grapevine Fanleaf Virus complex with Nanobody
Descriptor: Nanobody, RNA2 polyprotein
Authors:Orlov, I, Hemmer, C, Ackerer, L, Lorber, B, Ghannam, A, Poignavent, V, Hleibieh, K, Sauter, C, Schmitt-Keichinger, C, Belval, L, Hily, J.M, Marmonier, A, Komar, V, Gersch, S, Schellenberger, P, Bron, P, Vigne, E, Muyldermans, S, Lemaire, O, Demangeat, G, Ritzenthaler, C, Klaholz, B.P.
Deposit date:2015-11-22
Release date:2016-01-20
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of nanobody recognition of grapevine fanleaf virus and of virus resistance loss.
Proc.Natl.Acad.Sci.USA, 2020
4I0C
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BU of 4i0c by Molmil
The structure of the camelid antibody cAbHuL5 in complex with human lysozyme
Descriptor: CHLORIDE ION, GLYCEROL, Lysozyme C, ...
Authors:De Genst, E, Chan, P.H, Pardon, E, Kumita, J.R, Christodoulou, J, Menzer, L, Chirgadze, D.Y, Robinson, C.V, Muyldermans, S, Matagne, A, Wyns, L, Dobson, C.M, Dumoulin, M.
Deposit date:2012-11-16
Release date:2013-10-09
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
J.Phys.Chem.B, 117, 2013
3G9A
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BU of 3g9a by Molmil
Green fluorescent protein bound to minimizer nanobody
Descriptor: Green fluorescent protein, Minimizer
Authors:Kirchhofer, A, Helma, J, Schmidthals, K, Frauer, C, Cui, S, Karcher, A, Pellis, M, Muyldermans, S, Delucci, C.C, Cardoso, M.C, Leonhardt, H, Hopfner, K.-P, Rothbauer, U.
Deposit date:2009-02-13
Release date:2009-12-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.614 Å)
Cite:Modulation of protein properties in living cells using nanobodies
Nat.Struct.Mol.Biol., 17, 2010
8PE1
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BU of 8pe1 by Molmil
Crystal structure of Gel4 in complex with Nanobody 4
Descriptor: 1,3-beta-glucanosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 4, ...
Authors:Macias-Leon, J, Redrado-Hernandez, S, Castro-Lopez, J, Sanz, A.B, Arias, M, Farkas, V, Vincke, C, Muyldermans, S, Pardo, J, Arroyo, J, Galvez, E, Hurtado-Guerrero, R.
Deposit date:2023-06-13
Release date:2024-06-19
Last modified:2024-08-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases.
Angew.Chem.Int.Ed.Engl., 63, 2024
8PE2
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BU of 8pe2 by Molmil
Crystal structure of Gel4 in complex with Nanobody 3
Descriptor: 1,3-beta-glucanosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 3, ...
Authors:Macias-Leon, J, Redrado-Hernandez, S, Castro-Lopez, J, Sanz, A.B, Arias, M, Farkas, V, Vincke, C, Muyldermans, S, Pardo, J, Arroyo, J, Galvez, E, Hurtado-Guerrero, R.
Deposit date:2023-06-13
Release date:2024-06-19
Last modified:2024-08-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases.
Angew.Chem.Int.Ed.Engl., 63, 2024
3K1K
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BU of 3k1k by Molmil
Green fluorescent protein bound to enhancer nanobody
Descriptor: Enhancer, Green Fluorescent Protein
Authors:Kirchhofer, A, Helma, J, Schmidthals, K, Frauer, C, Cui, S, Karcher, A, Pellis, M, Muyldermans, S, Delucci, C.C, Cardoso, M.C, Leonhardt, H, Hopfner, K.-P, Rothbauer, U.
Deposit date:2009-09-28
Release date:2009-12-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Modulation of protein properties in living cells using nanobodies
Nat.Struct.Mol.Biol., 17, 2010
1GHC
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BU of 1ghc by Molmil
HOMO-AND HETERONUCLEAR TWO-DIMENSIONAL NMR STUDIES OF THE GLOBULAR DOMAIN OF HISTONE H1: FULL ASSIGNMENT, TERTIARY STRUCTURE, AND COMPARISON WITH THE GLOBULAR DOMAIN OF HISTONE H5
Descriptor: GH1
Authors:Cerf, C, Lippens, G, Ramakrishnan, V, Muyldermans, S, Segers, A, Wyns, L, Wodak, S.J, Hallenga, K.
Deposit date:1994-05-16
Release date:1994-08-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: full assignment, tertiary structure, and comparison with the globular domain of histone H5.
Biochemistry, 33, 1994
1F2X
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BU of 1f2x by Molmil
STRUCTURE OF THE SINGLE-DOMAIN CAMELID ANTIBODY CAB-CA05
Descriptor: ANTIBODY HEAVY CHAIN
Authors:Decanniere, K, Muyldermans, S, Wyns, L.
Deposit date:2000-05-30
Release date:2000-06-08
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Canonical antigen-binding loop structures in immunoglobulins: more structures, more canonical classes?
J.Mol.Biol., 300, 2000
1KXT
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BU of 1kxt by Molmil
Camelid VHH Domains in Complex with Porcine Pancreatic alpha-Amylase
Descriptor: ALPHA-AMYLASE, PANCREATIC, CALCIUM ION, ...
Authors:Desmyter, A, Spinelli, S, Payan, F, Lauwereys, M, Wyns, L, Muyldermans, S, Cambillau, C.
Deposit date:2002-02-01
Release date:2002-06-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.
J.Biol.Chem., 277, 2002
1KXQ
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BU of 1kxq by Molmil
Camelid VHH Domain in Complex with Porcine Pancreatic alpha-Amylase
Descriptor: CALCIUM ION, CHLORIDE ION, alpha-amylase, ...
Authors:Desmyter, A, Spinelli, S, Payan, F, Lauwereys, M, Wyns, L, Muyldermans, S, Cambillau, C.
Deposit date:2002-02-01
Release date:2002-06-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.
J.Biol.Chem., 277, 2002
1KXV
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BU of 1kxv by Molmil
Camelid VHH Domains in Complex with Porcine Pancreatic alpha-Amylase
Descriptor: ALPHA-AMYLASE, PANCREATIC, CAMELID VHH DOMAIN CAB10
Authors:Desmyter, A, Spinelli, S, Payan, F, Lauwereys, M, Wyns, L, Muyldermans, S, Cambillau, C.
Deposit date:2002-02-01
Release date:2002-06-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.
J.Biol.Chem., 277, 2002
3EBA
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BU of 3eba by Molmil
CAbHul6 FGLW mutant (humanized) in complex with human lysozyme
Descriptor: CAbHul6, Lysozyme C, SULFATE ION
Authors:Loris, R, Vincke, C, Saerens, D, Martinez-Rodriguez, S, Muyldermans, S, Conrath, K.
Deposit date:2008-08-27
Release date:2008-12-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold
J.Biol.Chem., 284, 2009
3EAK
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BU of 3eak by Molmil
NbBCII10 humanized (FGLA mutant)
Descriptor: NbBCII10-FGLA, SULFATE ION
Authors:Vincke, C, Loris, R, Saerens, D, Martinez-Rodriguez, S, Muyldermans, S, Conrath, K.
Deposit date:2008-08-26
Release date:2008-12-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.
J.Biol.Chem., 2008
3DWT
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BU of 3dwt by Molmil
Structure of CabBCII-10 nanobody
Descriptor: GLYCEROL, cAbBCII-10
Authors:Vincke, C, Loris, R, Muyldermans, S, Conrath, K.
Deposit date:2008-07-23
Release date:2008-12-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.
J.Biol.Chem., 2008
1JTT
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BU of 1jtt by Molmil
Degenerate interfaces in antigen-antibody complexes
Descriptor: FORMIC ACID, Lysozyme, SODIUM ION, ...
Authors:Decanniere, K, Transue, T.R, Desmyter, A, Maes, D, Muyldermans, S, Wyns, L.
Deposit date:2001-08-22
Release date:2001-12-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Degenerate interfaces in antigen-antibody complexes.
J.Mol.Biol., 313, 2001

 

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