3EAK

NbBCII10 humanized (FGLA mutant)

Summary for 3EAK

Entry DOI	10.2210/pdb3eak/pdb
Descriptor	NbBCII10-FGLA, SULFATE ION (3 entities in total)
Functional Keywords	antibody, nanobody, humanization, vhh domain, immune system
Biological source	Camelus dromedarius
Total number of polymer chains	2
Total formula weight	30067.45
Authors	Vincke, C.,Loris, R.,Saerens, D.,Martinez-Rodriguez, S.,Muyldermans, S.,Conrath, K. (deposition date: 2008-08-26, release date: 2008-12-02, Last modification date: 2023-11-01)
Primary citation	Vincke, C.,Loris, R.,Saerens, D.,Martinez-Rodriguez, S.,Muyldermans, S.,Conrath, K. General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold. J.Biol.Chem., 2008 Cited by PubMed: 19010777 DOI: 10.1074/jbc.M806889200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation