4LAK | | CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE D323N MUTANT IN APO FORM | | Descriptor: | Uracil-5-carboxylate decarboxylase, ZINC ION | | Authors: | Xu, S., Li, W., Zhu, J., Wang, R., Li, Z., Xu, G.L., Ding, J. | | Deposit date: | 2013-06-20 | | Release date: | 2013-10-02 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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4LAL | | CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE D323A MUTANT IN COMPLEX WITH 5-CARBOXYL-URACIL | | Descriptor: | Uracil-5-carboxylate decarboxylase, ZINC ION, 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, ... | | Authors: | Xu, S., Li, W., Zhu, J., Ding, J. | | Deposit date: | 2013-06-20 | | Release date: | 2013-10-02 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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4LAM | | CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE D323N MUTANT IN COMPLEX WITH 5-CARBOXYL-URACIL | | Descriptor: | Uracil-5-carboxylate decarboxylase, ZINC ION, 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, ... | | Authors: | Xu, S., Li, W., Zhu, J., Ding, J. | | Deposit date: | 2013-06-20 | | Release date: | 2013-10-02 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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4LAN | | CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE H195A MUTANT | | Descriptor: | Uracil-5-carboxylate decarboxylase, ZINC ION | | Authors: | Xu, S., Li, W., Zhu, J., Ding, J. | | Deposit date: | 2013-06-20 | | Release date: | 2013-10-02 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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4LAO | | CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE H195A MUTANT (ZN) | | Descriptor: | Cordyceps militaris IDCase, ZINC ION, DI(HYDROXYETHYL)ETHER | | Authors: | Xu, S., Li, W., Zhu, J., Ding, J. | | Deposit date: | 2013-06-20 | | Release date: | 2013-10-02 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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4UQ8 | | ELECTRON CRYO-MICROSCOPY OF BOVINE COMPLEX I | | Descriptor: | NADH UBIQUINONE OXIDOREDUCTASE CHAIN 3, NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL, ... | | Authors: | Vinothkumar, K.R., Zhu, J., Hirst, J. | | Deposit date: | 2014-06-21 | | Release date: | 2014-10-01 | | Last modified: | 2017-08-02 | | Method: | ELECTRON MICROSCOPY (4.95 Å) | | Cite: | Architecture of Mammalian Respiratory Complex I.
Nature, 515, 2014
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5GK9 | | CRYSTAL STRUCTURE OF HUMAN HBO1 IN COMPLEX WITH BRPF2 | | Descriptor: | Histone acetyltransferase KAT7, BRD1 protein, ZINC ION, ... | | Authors: | Tao, Y., Zhu, J., Xu, S., Ding, J. | | Deposit date: | 2016-07-04 | | Release date: | 2017-03-29 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and mechanistic insights into regulation of HBO1 histone acetyltransferase activity by BRPF2.
Nucleic Acids Res., 45, 2017
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5XZR | | THE ATOMIC STRUCTURE OF SHP2 E76A MUTANT IN COMPLEX WITH ALLOSTERIC INHIBITOR 9B | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 11, 4-(3-phenylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3-thiazol-2-amine | | Authors: | Li, D., Xie, J., Zhu, J., Liu, C. | | Deposit date: | 2017-07-13 | | Release date: | 2017-12-13 | | Last modified: | 2018-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment.
J. Med. Chem., 60, 2017
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6JLS | | CRYSTAL STRUCTURE OF FMN-DEPENDENT CYSTEINE DECARBOXYLASES TVAF FROM THIOVIRIDAMIDE BIOSYNTHESIS | | Descriptor: | Putative flavoprotein decarboxylase, FLAVIN MONONUCLEOTIDE | | Authors: | Li, J., Lu, J., Wang, H., Zhu, J. | | Deposit date: | 2019-03-06 | | Release date: | 2019-06-26 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Characterization of the FMN-Dependent Cysteine Decarboxylase from Thioviridamide Biosynthesis.
Org.Lett., 21, 2019
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2VC2 | | RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO ANTAGONIST L-739758 | | Descriptor: | INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, MONOCLONAL ANTIBODY 10E5 HEAVY CHAIN, ... | | Authors: | Springer, T.A., Zhu, J., Xiao, T. | | Deposit date: | 2007-09-18 | | Release date: | 2008-09-02 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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2VDK | | RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE | | Descriptor: | INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, MONOCLONAL ANTIBODY 10E5 HEAVY CHAIN, ... | | Authors: | Springer, T.A., Zhu, J., Xiao, T. | | Deposit date: | 2007-10-10 | | Release date: | 2008-09-02 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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2VDL | | RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE | | Descriptor: | INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, MONOCLONAL ANTIBODY 10E5 HEAVY CHAIN, ... | | Authors: | Springer, T.A., Zhu, J., Xiao, T. | | Deposit date: | 2007-10-10 | | Release date: | 2008-09-02 | | Last modified: | 2019-02-06 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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2VDM | | RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO ANTAGONIST TIROFIBAN | | Descriptor: | INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, MONOCLONAL ANTIBODY 10E5 HEAVY CHAIN, ... | | Authors: | Springer, T.A., Zhu, J., Xiao, T. | | Deposit date: | 2007-10-10 | | Release date: | 2008-09-02 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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2VDN | | RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO ANTAGONIST EPTIFIBATIDE | | Descriptor: | INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, EPTIFIBATIDE, ... | | Authors: | Springer, T.A., Zhu, J., Xiao, T. | | Deposit date: | 2007-10-10 | | Release date: | 2008-09-02 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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2VDO | | INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO FIBRINOGEN GAMMA CHAIN PEPTIDE, HHLGGAKQAGDV | | Descriptor: | INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, FIBRINOGEN, ... | | Authors: | Springer, T.A., Zhu, J., Xiao, T. | | Deposit date: | 2007-10-10 | | Release date: | 2008-09-02 | | Last modified: | 2019-02-06 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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2VDP | | INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO FIBRINOGEN GAMMA CHAIN PEPTIDE,LGGAKQAGDV | | Descriptor: | INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, FIBRINOGEN, ... | | Authors: | Springer, T.A., Zhu, J., Xiao, T. | | Deposit date: | 2007-10-10 | | Release date: | 2008-09-02 | | Last modified: | 2019-02-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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2VDQ | | INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO A CHIMERIC FIBRINOGEN GAMMA CHAIN PEPTIDE, HHLGGAKQRGDV | | Descriptor: | INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, FIBRINOGEN, ... | | Authors: | Springer, T.A., Zhu, J., Xiao, T. | | Deposit date: | 2007-10-10 | | Release date: | 2008-09-02 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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2VDR | | INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO A CHIMERIC FIBRINOGEN GAMMA CHAIN PEPTIDE, LGGAKQRGDV | | Descriptor: | INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, FIBRINOGEN, ... | | Authors: | Springer, T.A., Zhu, J., Xiao, T. | | Deposit date: | 2007-10-10 | | Release date: | 2008-09-02 | | Last modified: | 2019-02-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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3DBC | | CRYSTAL STRUCTURE OF AN ACTIVATED (THR->ASP) POLO-LIKE KINASE 1 (PLK1) CATALYTIC DOMAIN IN COMPLEX WITH COMPOUND 257 | | Descriptor: | Polo-like kinase 1, 3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide | | Authors: | Elling, R.A., Zhu, J., Barr, K.J., Romanowski, M.J. | | Deposit date: | 2008-05-31 | | Release date: | 2008-10-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
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3DBF | | CRYSTAL STRUCTURE OF AN ACTIVATED (THR->ASP) POLO-LIKE KINASE 1 (PLK1) CATALYTIC DOMAIN IN COMPLEX WITH COMPOUND 562 | | Descriptor: | Polo-like kinase, 4-({1-[3-(3-amino-3-oxopropyl)-5-chlorophenyl]-3-methyl-1H-pyrazolo[4,3-c]pyridin-6-yl}amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | | Authors: | Elling, R.A., Zhu, J., Barr, K.J., Romanowski, M.J. | | Deposit date: | 2008-05-31 | | Release date: | 2008-10-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
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3H3B | | CRYSTAL STRUCTURE OF THE SINGLE-CHAIN FV (SCFV) FRAGMENT OF AN ANTI-ERBB2 ANTIBODY CHA21 IN COMPLEX WITH RESIDUES 1-192 OF ERBB2 EXTRACELLULAR DOMAIN | | Descriptor: | Receptor tyrosine-protein kinase erbB-2, anti-ErbB2 antibody chA21 | | Authors: | Zhou, H., Liu, Y., Niu, L., Zhu, J., Teng, M. | | Deposit date: | 2009-04-16 | | Release date: | 2010-04-28 | | Last modified: | 2011-09-28 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural Insights into the Down-regulation of Overexpressed p185her2/neu Protein of Transformed Cells by the Antibody chA21.
J.Biol.Chem., 286, 2011
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3K6S | | STRUCTURE OF INTEGRIN ALPHAXBETA2 ECTODOMAIN | | Descriptor: | Integrin alpha-X, Integrin beta-2, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Xie, C., Zhu, J., Chen, X., Mi, L., Nishida, N., Springer, T.A. | | Deposit date: | 2009-10-09 | | Release date: | 2010-01-12 | | Last modified: | 2018-06-20 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
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3K71 | | STRUCTURE OF INTEGRIN ALPHAX BETA2 ECTODOMAIN | | Descriptor: | Integrin alpha-X, Integrin beta-2, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Xie, C., Zhu, J., Chen, X., Mi, L., Nishida, N., Springer, T.A. | | Deposit date: | 2009-10-11 | | Release date: | 2010-01-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.95 Å) | | Cite: | Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
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3K72 | | STRUCTURE OF INTEGRIN ALPHAX BETA2 | | Descriptor: | Integrin alpha-X, Integrin beta-2, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Xie, C., Zhu, J., Chen, X., Mi, L., Nishida, N., Springer, T.A. | | Deposit date: | 2009-10-11 | | Release date: | 2010-01-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
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3MME | | STRUCTURE AND FUNCTIONAL DISSECTION OF PG16, AN ANTIBODY WITH BROAD AND POTENT NEUTRALIZATION OF HIV-1 | | Descriptor: | PG16 HEAVY CHAIN FAB, PG16 LIGHT CHAIN FAB, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Pancera, M., McLellan, J., Zhou, T., Zhu, J., Kwong, P. | | Deposit date: | 2010-04-19 | | Release date: | 2010-06-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.97 Å) | | Cite: | Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1.
J.Virol., 84, 2010
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