2XS2
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2XS7
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2XSF
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2XS5
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5MFX
| Zika NS3 helicase:RNA complex | Descriptor: | ACETATE ION, CITRATE ANION, Genome polyprotein, ... | Authors: | Jenkins, H.T, Ge, M, Chechik, M, Greive, S.J, Antson, A.A. | Deposit date: | 2016-11-18 | Release date: | 2017-01-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.598 Å) | Cite: | How Zika virus NS3 helicase grips the first
nucleotide of the leading RNA strand To Be Published
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3GVO
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3GVT
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2A55
| Solution structure of the two N-terminal CCP modules of C4b-binding protein (C4BP) alpha-chain. | Descriptor: | C4b-binding protein | Authors: | Jenkins, H.T, Mark, L, Ball, G, Lindahl, G, Uhrin, D, Blom, A.M, Barlow, P.N. | Deposit date: | 2005-06-30 | Release date: | 2005-12-13 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Human C4b-binding Protein, Structural Basis for Interaction with Streptococcal M Protein, a Major Bacterial Virulence Factor J.Biol.Chem., 281, 2006
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7NT6
| CryoEM structure of the Nipah virus nucleocapsid spiral clam-shaped assembly | Descriptor: | Nucleoprotein, RNA (42-MER), RNA (48-MER) | Authors: | Ker, D.S, Jenkins, H.T, Greive, S.J, Antson, A.A. | Deposit date: | 2021-03-09 | Release date: | 2021-07-07 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | CryoEM structure of the Nipah virus nucleocapsid assembly. Plos Pathog., 17, 2021
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5M1N
| Crystal structure of the large terminase nuclease from thermophilic phage G20c with bound Manganese | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, Phage terminase large subunit, ... | Authors: | Xu, R.G, Jenkins, H.T, Chechik, M, Blagova, E.V, Greive, S.J, Antson, A.A. | Deposit date: | 2016-10-09 | Release date: | 2016-10-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism. Nucleic Acids Res., 45, 2017
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8POP
| HK97 small terminase in complex with DNA | Descriptor: | DNA (31-MER), Terminase small subunit | Authors: | Chechik, M, Greive, S.J, Antson, A.A, Jenkins, H.T. | Deposit date: | 2023-07-05 | Release date: | 2023-08-09 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for DNA recognition by a viral genome-packaging machine. Proc.Natl.Acad.Sci.USA, 121, 2024
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7AVJ
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4XP7
| Crystal structure of Human tRNA dihydrouridine synthase 2 | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | Authors: | Whelan, F, Jenkins, H.T, Griffiths, S, Byrne, R.T, Dodson, E.J, Antson, A.A. | Deposit date: | 2015-01-16 | Release date: | 2015-01-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | From bacterial to human dihydrouridine synthase: automated structure determination. Acta Crystallogr.,Sect.D, 71, 2015
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4XVN
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7NT5
| CryoEM structure of the Nipah virus nucleocapsid single helical turn assembly | Descriptor: | Nucleoprotein, RNA (78-MER) | Authors: | Ker, D.S, Jenkins, H.T, Greive, S.J, Antson, A.A. | Deposit date: | 2021-03-09 | Release date: | 2021-07-07 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | CryoEM structure of the Nipah virus nucleocapsid assembly. Plos Pathog., 17, 2021
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7AVH
| Streptococcal High Identity Repeats in Tandem (SHIRT) domains 3-4 from cell surface protein SGO_0707 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, LPXTG cell wall surface protein | Authors: | Whelan, F, Jenkins, H.T, Potts, J.R. | Deposit date: | 2020-11-05 | Release date: | 2021-06-09 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Periscope Proteins are variable-length regulators of bacterial cell surface interactions. Proc.Natl.Acad.Sci.USA, 118, 2021
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7AVK
| Streptococcal High Identity Repeats in Tandem (SHIRT) domain 10 from cell surface protein SGO_0707 | Descriptor: | LPXTG cell wall surface protein, isothiocyanate | Authors: | Degut, C, Gilburt, J, Whelan, F, Jenkins, H.T, Potts, J.R. | Deposit date: | 2020-11-05 | Release date: | 2021-06-09 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (0.82 Å) | Cite: | Periscope Proteins are variable-length regulators of bacterial cell surface interactions. Proc.Natl.Acad.Sci.USA, 118, 2021
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6SE1
| Structure of Salmonella ser. Paratyphi A lipopolysaccharide acetyltransferase periplasmic domain | Descriptor: | DI(HYDROXYETHYL)ETHER, Putative lipopolysaccharide modification acyltransferase, SULFATE ION | Authors: | Tindall, S.N, Pearson, C, Herman, R, Jenkins, H.T, Thomas, G.H, Potts, J.R, Van der Woude, M. | Deposit date: | 2019-07-29 | Release date: | 2020-08-26 | Last modified: | 2020-09-16 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Acetylation of Surface Carbohydrates in Bacterial Pathogens Requires Coordinated Action of a Two-Domain Membrane-Bound Acyltransferase. Mbio, 11, 2020
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6RWZ
| Structure of Zika virus NS3 helicase in complex with ADP-BeF3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MANGANESE (II) ION, ... | Authors: | Ge, M, Molt Jr, R.W, Jenkins, H.T, Blackburn, G.M, Jin, Y, Antson, A.A. | Deposit date: | 2019-06-07 | Release date: | 2020-07-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Octahedral Trifluoromagnesate, an Anomalous Metal Fluoride Species, Stabilizes the Transition State in a Biological Motor. Acs Catalysis, 11, 2021
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6S0J
| Structure of Zika virus NS3 helicase in complex with ADP-MgF3(H2O)- | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ... | Authors: | Ge, M, Molt Jr, R.W, Jenkins, H.T, Blackburn, G.M, Jin, Y, Antson, A.A. | Deposit date: | 2019-06-16 | Release date: | 2020-07-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Octahedral Trifluoromagnesate, an Anomalous Metal Fluoride Species, Stabilizes the Transition State in a Biological Motor. Acs Catalysis, 11, 2021
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4YCP
| E. coli dihydrouridine synthase C (DusC) in complex with tRNATrp | Descriptor: | FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Byrne, R.T, Jenkins, H.T, Peters, D.T, Whelan, F, Stowell, J, Aziz, N, Kasatsky, P, Rodnina, M.V, Koonin, E.V, Konevega, A.L, Antson, A.A. | Deposit date: | 2015-02-20 | Release date: | 2015-04-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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4ZC3
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4YCO
| E. coli dihydrouridine synthase C (DusC) in complex with tRNAPhe | Descriptor: | FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Byrne, R.T, Jenkins, H.T, Peters, D.T, Whelan, F, Stowell, J, Aziz, N, Kasatsky, P, Rodnina, M.V, Koonin, E.V, Konevega, A.L, Antson, A.A. | Deposit date: | 2015-02-20 | Release date: | 2015-04-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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5NGD
| Crystal structure of the V325G mutant of the bacteriophage G20C portal protein | Descriptor: | Portal protein | Authors: | Pascoa, T, Jenkins, H.T, Chechik, M, Greive, S.J, Antson, A.A. | Deposit date: | 2017-03-17 | Release date: | 2017-03-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Porphyrin-Assisted Docking of a Thermophage Portal Protein into Lipid Bilayers: Nanopore Engineering and Characterization Acs Nano, 11, 2017
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5OE9
| Structure of large terminase from the thermophilic bacteriophage D6E in complex with sulfate (Crystal form 2) | Descriptor: | Large subunit terminase, SULFATE ION | Authors: | Xu, R.G, Jenkins, H.T, Greive, S.J, Antson, A.A. | Deposit date: | 2017-07-07 | Release date: | 2017-10-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the large terminase from a hyperthermophilic virus reveals a unique mechanism for oligomerization and ATP hydrolysis. Nucleic Acids Res., 45, 2017
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