1Q9P
| Solution structure of the mature HIV-1 protease monomer | Descriptor: | HIV-1 Protease | Authors: | Ishima, R, Torchia, D.A, Lynch, S.M, Gronenborn, A.M, Louis, J.M. | Deposit date: | 2003-08-25 | Release date: | 2004-03-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the mature HIV-1 protease monomer: Insight into the tertiary fold and stability of a precursor J.Biol.Chem., 278, 2003
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3L3F
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1GUR
| GURMARIN, A SWEET TASTE-SUPPRESSING POLYPEPTIDE, NMR, 10 STRUCTURES | Descriptor: | GURMARIN | Authors: | Arai, K, Ishima, R, Morikawa, S, Imoto, T, Yoshimura, S, Aimoto, S, Akasaka, K. | Deposit date: | 1996-03-12 | Release date: | 1996-08-01 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | Three-dimensional structure of gurmarin, a sweet taste-suppressing polypeptide. J.Biomol.NMR, 5, 1995
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1JOY
| SOLUTION STRUCTURE OF THE HOMODIMERIC DOMAIN OF ENVZ FROM ESCHERICHIA COLI BY MULTI-DIMENSIONAL NMR. | Descriptor: | PROTEIN (ENVZ_ECOLI) | Authors: | Tomomori, C, Tanaka, T, Dutta, R, Park, H, Saha, S.K, Zhu, Y, Ishima, R, Liu, D, Tong, K.I, Kurokawa, H, Qian, H, Inouye, M, Ikura, M. | Deposit date: | 1998-12-28 | Release date: | 2000-01-12 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the homodimeric core domain of Escherichia coli histidine kinase EnvZ. Nat.Struct.Biol., 6, 1999
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1BXD
| NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (OSMOLARITY SENSOR PROTEIN (ENVZ)) | Authors: | Tanaka, T, Saha, S.K, Tomomori, C, Ishima, R, Liu, D, Tong, K.I, Park, H, Dutta, R, Qin, L, Swindells, M.B, Yamazaki, T, Ono, A.M, Kainosho, M, Inouye, M, Ikura, M. | Deposit date: | 1998-10-02 | Release date: | 1999-10-02 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | NMR structure of the histidine kinase domain of the E. coli osmosensor EnvZ. Nature, 396, 1998
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1JSA
| MYRISTOYLATED RECOVERIN WITH TWO CALCIUMS BOUND, NMR, 24 STRUCTURES | Descriptor: | CALCIUM ION, MYRISTIC ACID, RECOVERIN | Authors: | Ames, J.B, Ishima, R, Tanaka, T, Gordon, J.I, Stryer, L, Ikura, M. | Deposit date: | 1997-06-04 | Release date: | 1997-10-15 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Molecular mechanics of calcium-myristoyl switches. Nature, 389, 1997
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1TBA
| SOLUTION STRUCTURE OF A TBP-TAFII230 COMPLEX: PROTEIN MIMICRY OF THE MINOR GROOVE SURFACE OF THE TATA BOX UNWOUND BY TBP, NMR, 25 STRUCTURES | Descriptor: | TRANSCRIPTION INITIATION FACTOR IID 230K CHAIN, TRANSCRIPTION INITIATION FACTOR TFIID | Authors: | Liu, D, Ishima, R, Tong, K.I, Bagby, S, Kokubo, T, Muhandiram, D.R, Kay, L.E, Nakatani, Y, Ikura, M. | Deposit date: | 1998-08-16 | Release date: | 1999-08-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of a TBP-TAF(II)230 complex: protein mimicry of the minor groove surface of the TATA box unwound by TBP. Cell(Cambridge,Mass.), 94, 1998
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3JVY
| HIV-1 Protease Mutant G86A with DARUNAVIR | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, Gag-Pol polyprotein, ... | Authors: | Tie, Y, Weber, I.T. | Deposit date: | 2009-09-17 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Highly conserved glycine 86 and arginine 87 residues contribute differently to the structure and activity of the mature HIV-1 protease Proteins, 78, 2009
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3JVW
| HIV-1 Protease Mutant G86A with symmetric inhibitor DMP323 | Descriptor: | Gag-Pol polyprotein, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-[1,3-BIS([4-HYDROXYMETHYL-PHENYL]METHYL)-4,7-BIS(PHEN YLMETHYL)]-2H-1,3-DIAZEPINONE | Authors: | Tie, Y, Weber, I.T. | Deposit date: | 2009-09-17 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Highly conserved glycine 86 and arginine 87 residues contribute differently to the structure and activity of the mature HIV-1 protease Proteins, 78, 2009
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3JW2
| HIV-1 Protease Mutant G86S with DARUNAVIR | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, Gag-Pol polyprotein, ... | Authors: | Tie, Y, Weber, I.T. | Deposit date: | 2009-09-17 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Highly conserved glycine 86 and arginine 87 residues contribute differently to the structure and activity of the mature HIV-1 protease Proteins, 78, 2009
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1C4E
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3BVB
| Cystal structure of HIV-1 Active Site Mutant D25N and inhibitor Darunavir | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, GLYCEROL, ... | Authors: | Liu, F, Weber, I.T. | Deposit date: | 2008-01-05 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Effect of the Active Site D25N Mutation on the Structure, Stability, and Ligand Binding of the Mature HIV-1 Protease. J.Biol.Chem., 283, 2008
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3BVA
| Cystal structure of HIV-1 Active Site Mutant D25N and p2-NC analog inhibitor | Descriptor: | GLYCEROL, N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, Protease (Retropepsin) | Authors: | Liu, F, Weber, I.T. | Deposit date: | 2008-01-05 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Effect of the Active Site D25N Mutation on the Structure, Stability, and Ligand Binding of the Mature HIV-1 Protease. J.Biol.Chem., 283, 2008
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5UV5
| Crystal Structure of a 2-Hydroxyisoquinoline-1,3-dione RNase H Active Site Inhibitor with Multiple Binding Modes to HIV Reverse Transcriptase | Descriptor: | 7-(furan-2-yl)-2-hydroxyisoquinoline-1,3(2H,4H)-dione, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H, ... | Authors: | Kirby, K.A, Sarafianos, S.G. | Deposit date: | 2017-02-19 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A 2-Hydroxyisoquinoline-1,3-Dione Active-Site RNase H Inhibitor Binds in Multiple Modes to HIV-1 Reverse Transcriptase. Antimicrob. Agents Chemother., 61, 2017
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8FSL
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4DIR
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2L4J
| Yap ww2 | Descriptor: | Yes-associated protein 2 (YAP2) | Authors: | Webb, C, Upadhyay, A, Furutani-Seiki, M, Bagby, S. | Deposit date: | 2010-10-07 | Release date: | 2010-11-03 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural Features and Ligand Binding Properties of Tandem WW Domains from YAP and TAZ, Nuclear Effectors of the Hippo Pathway. Biochemistry, 50, 2011
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3RM1
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3RLZ
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6FB4
| human KIBRA C2 domain mutant C771A | Descriptor: | GLYCEROL, PHOSPHATE ION, Protein KIBRA | Authors: | Crennell, S.J, Posner, M.G, Bagby, S. | Deposit date: | 2017-12-18 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.415631 Å) | Cite: | Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018
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6FJC
| Human KIBRA C2 domain mutant C771A in complex with phosphatidylinositol 3,4,5-trisphosphate | Descriptor: | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, GLYCEROL, Protein KIBRA, ... | Authors: | Crennell, S.J, Posner, M.G, Bagby, S. | Deposit date: | 2018-01-22 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.598 Å) | Cite: | Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018
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6FJD
| Human KIBRA C2 domain mutant C771A in complex with phosphatidylinositol 4,5-bisphosphate | Descriptor: | (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, GLYCEROL, Protein KIBRA, ... | Authors: | Crennell, S.J, Posner, M.G, Bagby, S. | Deposit date: | 2018-01-22 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.898 Å) | Cite: | Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018
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6FD0
| Human KIBRA C2 domain mutant M734I S735A | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Protein KIBRA | Authors: | Crennell, S.J, Posner, M.G, Bagby, S. | Deposit date: | 2017-12-21 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.64215851 Å) | Cite: | Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018
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1TFB
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