8TAH
| Cryo-EM structure of Cortactin-bound to Arp2/3 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ... | Authors: | Fregoso, F.E, van Eeuwen, T, Dominguez, R. | Deposit date: | 2023-06-27 | Release date: | 2023-09-27 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Mechanism of synergistic activation of Arp2/3 complex by cortactin and WASP-family proteins. Nat Commun, 14, 2023
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5O0U
| Crystal structure of tarantula venom peptide Protoxin-II | Descriptor: | 1,2-ETHANEDIOL, Beta/omega-theraphotoxin-Tp2a, CHLORIDE ION | Authors: | Tabor, A, McCarthy, S, Reyes, F.E. | Deposit date: | 2017-05-17 | Release date: | 2017-09-13 | Last modified: | 2019-03-27 | Method: | X-RAY DIFFRACTION (0.99 Å) | Cite: | The Role of Disulfide Bond Replacements in Analogues of the Tarantula Toxin ProTx-II and Their Effects on Inhibition of the Voltage-Gated Sodium Ion Channel Nav1.7. J.Am.Chem.Soc., 139, 2017
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5OJJ
| Crystal structure of the Zn-bound ubiquitin-conjugating enzyme Ube2T | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Ubiquitin-conjugating enzyme E2 T, ... | Authors: | Morreale, F.E, Testa, A, Chaugule, V.K, Bortoluzzi, A, Ciulli, A, Walden, H. | Deposit date: | 2017-07-21 | Release date: | 2017-10-04 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements. J. Med. Chem., 60, 2017
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4ER4
| HIGH-RESOLUTION X-RAY ANALYSES OF RENIN INHIBITOR-ASPARTIC PROTEINASE COMPLEXES | Descriptor: | ENDOTHIAPEPSIN, H-142 | Authors: | Foundling, S.I, Watson, F.E, Szelke, M, Blundell, T.L. | Deposit date: | 1991-01-05 | Release date: | 1991-04-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes. Nature, 327, 1987
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6OIF
| Cryo-EM structure of human TorsinA filament | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Torsin-1A | Authors: | Zheng, W, Demircioglu, F.E, Schwartz, T.U, Egelman, E.H. | Deposit date: | 2019-04-09 | Release date: | 2019-07-24 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn. Nat Commun, 10, 2019
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4FRN
| Crystal structure of the cobalamin riboswitch regulatory element | Descriptor: | BARIUM ION, Cobalamin riboswitch aptamer domain, Hydroxocobalamin | Authors: | Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. | Deposit date: | 2012-06-26 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.43 Å) | Cite: | B12 cofactors directly stabilize an mRNA regulatory switch. Nature, 492, 2012
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4FRG
| Crystal structure of the cobalamin riboswitch aptamer domain | Descriptor: | Hydroxocobalamin, IRIDIUM (III) ION, MAGNESIUM ION, ... | Authors: | Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. | Deposit date: | 2012-06-26 | Release date: | 2012-10-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | B12 cofactors directly stabilize an mRNA regulatory switch. Nature, 492, 2012
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4GMA
| Crystal structure of the adenosylcobalamin riboswitch | Descriptor: | Adenosylcobalamin, Adenosylcobalamin riboswitch | Authors: | Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. | Deposit date: | 2012-08-15 | Release date: | 2012-10-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.94 Å) | Cite: | B12 cofactors directly stabilize an mRNA regulatory switch. Nature, 492, 2012
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2XO1
| xpt-pbuX C74U Riboswitch from B. subtilis bound to N6-methyladenine | Descriptor: | ACETATE ION, COBALT HEXAMMINE(III), Guanine riboswitch, ... | Authors: | Daldrop, P, Reyes, F.E, Robinson, D.A, Hammond, C.M, Lilley, D.M.J, Batey, R.T, Brenk, R. | Deposit date: | 2010-08-09 | Release date: | 2011-04-06 | Last modified: | 2018-06-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Novel ligands for a purine riboswitch discovered by RNA-ligand docking. Chem. Biol., 18, 2011
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3NPQ
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3NPN
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2XO0
| xpt-pbuX C74U Riboswitch from B. subtilis bound to 24-diamino-1,3,5- triazine identified by virtual screening | Descriptor: | 1,3,5-TRIAZINE-2,4-DIAMINE, ACETATE ION, COBALT HEXAMMINE(III), ... | Authors: | Daldrop, P, Reyes, F.E, Robinson, D.A, Hammond, C.M, Lilley, D.M.J, Batey, R.T, Brenk, R. | Deposit date: | 2010-08-09 | Release date: | 2011-04-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Novel ligands for a purine riboswitch discovered by RNA-ligand docking. Chem. Biol., 18, 2011
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2XNZ
| xpt-pbuX C74U Riboswitch from B. subtilis bound to acetoguanamine identified by virtual screening | Descriptor: | 6-METHYL-1,3,5-TRIAZINE-2,4-DIAMINE, ACETATE ION, COBALT HEXAMMINE(III), ... | Authors: | Daldrop, P, Reyes, F.E, Robinson, D.A, Hammond, C.M, Lilley, D.M.J, Batey, R.T, Brenk, R. | Deposit date: | 2010-08-06 | Release date: | 2011-04-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Novel ligands for a purine riboswitch discovered by RNA-ligand docking. Chem. Biol., 18, 2011
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2XNW
| XPT-PBUX C74U RIBOSWITCH FROM B. SUBTILIS BOUND TO A TRIAZOLO- TRIAZOLE-DIAMINE LIGAND IDENTIFIED BY VIRTUAL SCREENING | Descriptor: | 3,6-diamino-1,5-dihydro[1,2,4]triazolo[4,3-b][1,2,4]triazol-4-ium, ACETATE ION, COBALT HEXAMMINE(III), ... | Authors: | Daldrop, P, Reyes, F.E, Robinson, D.A, Hammond, C.M, Lilley, D.M.J, Brenk, R. | Deposit date: | 2010-08-06 | Release date: | 2011-04-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Novel ligands for a purine riboswitch discovered by RNA-ligand docking. Chem. Biol., 18, 2011
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6CSF
| Crystal structure of sodium/alanine symporter AgcS with D-alanine bound | Descriptor: | D-ALANINE, Monoclonal antibody FAB heavy chain, Monoclonal antibody FAB light chain, ... | Authors: | Ma, J, Reyes, F.E, Gonen, T. | Deposit date: | 2018-03-20 | Release date: | 2019-01-30 | Last modified: | 2019-02-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for substrate binding and specificity of a sodium-alanine symporter AgcS. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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1A4J
| DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR | Descriptor: | IMMUNOGLOBULIN, DIELS ALDER CATALYTIC ANTIBODY (HEAVY CHAIN), DIELS ALDER CATALYTIC ANTIBODY (LIGHT CHAIN) | Authors: | Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. | Deposit date: | 1998-01-30 | Release date: | 1998-05-13 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Immunological origins of binding and catalysis in a Diels-Alderase antibody. Science, 279, 1998
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1A4K
| DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE | Descriptor: | ANTIBODY FAB, CADMIUM ION, [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID | Authors: | Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. | Deposit date: | 1998-01-30 | Release date: | 1998-05-13 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Immunological origins of binding and catalysis in a Diels-Alderase antibody. Science, 279, 1998
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1B07
| CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR | Descriptor: | PHENYLETHANE, PROTEIN (PROTO-ONCOGENE CRK (CRK)), PROTEIN (SH3 PEPTOID INHIBITOR) | Authors: | Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. | Deposit date: | 1998-11-17 | Release date: | 1999-01-06 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science, 282, 1998
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5AMU
| IglE I39A,Y40A,V44A | Descriptor: | IGLE | Authors: | Robb, C.S, Nano, F.E, Boraston, A.B. | Deposit date: | 2015-09-01 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Structure, Dimerisation and Impact on Intramacrophage Replication of Igle in Francisella Novicida To be Published
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5AMT
| Intracellular growth locus protein E | Descriptor: | 1,2-ETHANEDIOL, BROMIDE ION, IGLE | Authors: | Robb, C.S, Nano, F.E, Boraston, A.B. | Deposit date: | 2015-09-01 | Release date: | 2016-10-05 | Last modified: | 2016-11-16 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Cloning, Expression, Purification, Crystallization and Preliminary X-Ray Diffraction Analysis of Intracellular Growth Locus E (Igle) Protein from Francisella Tularensis Subsp. Novicida. Acta Crystallogr.,Sect.F, 66, 2010
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7JPN
| Cryo-EM structure of Arpin-bound Arp2/3 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... | Authors: | van Eeuwen, T, Fregoso, F.E, Dominguez, R, Zimmet, A, Boczkowska, M, Rebowski, G. | Deposit date: | 2020-08-09 | Release date: | 2022-02-09 | Last modified: | 2022-08-24 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Molecular mechanism of Arp2/3 complex inhibition by Arpin. Nat Commun, 13, 2022
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8EEY
| Cas7-11 in complex with DR-mismatched target RNA, Csx29 and Csx30 | Descriptor: | Cas7-11, Csx29, Csx30, ... | Authors: | Demircioglu, F.E, Wilkinson, M.E, Strecker, J, Li, D, Faure, G, Macrae, R.K, Zhang, F. | Deposit date: | 2022-09-07 | Release date: | 2022-11-16 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | RNA-activated protein cleavage with a CRISPR-associated endopeptidase. Science, 378, 2022
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8EEX
| Cas7-11 in complex with Csx29 | Descriptor: | Cas7-11, Csx29, ZINC ION, ... | Authors: | Demircioglu, F.E, Wilkinson, M.E, Strecker, J, Li, D, Faure, G, Macrae, R.K, Zhang, F. | Deposit date: | 2022-09-07 | Release date: | 2022-11-16 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | RNA-activated protein cleavage with a CRISPR-associated endopeptidase. Science, 378, 2022
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1DO6
| CRYSTAL STRUCTURE OF SUPEROXIDE REDUCTASE IN THE OXIDIZED STATE AT 2.0 ANGSTROM RESOLUTION | Descriptor: | FE (III) ION, SUPEROXIDE REDUCTASE | Authors: | Yeh, A.P, Hu, Y, Jenney Junior, F.E, Adams, M.W, Rees, D.C. | Deposit date: | 1999-12-19 | Release date: | 2000-03-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the superoxide reductase from Pyrococcus furiosus in the oxidized and reduced states. Biochemistry, 39, 2000
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1DYZ
| OXIDISED AZURIN II FROM ALCALIGENES XYLOSOXIDANS | Descriptor: | AZURIN II, COPPER (II) ION | Authors: | Dodd, F.E, Abraham, Z.H.L, Eady, R.R, Hasnain, S.S. | Deposit date: | 2000-02-11 | Release date: | 2000-07-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structures of Oxidised and Reduced Azurin II from Alcaligenes Xylosoxidans at 1.75 Angstoms Resolution Acta Crystallogr.,Sect.D, 56, 2000
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