8TAH
Cryo-EM structure of Cortactin-bound to Arp2/3 complex
Summary for 8TAH
| Entry DOI | 10.2210/pdb8tah/pdb |
| EMDB information | 41135 |
| Descriptor | Actin-related protein 3, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, ... (10 entities in total) |
| Functional Keywords | complex, migration, actin, cytoskeleton, contractile protein |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 8 |
| Total formula weight | 234569.40 |
| Authors | Fregoso, F.E.,van Eeuwen, T.,Dominguez, R. (deposition date: 2023-06-27, release date: 2023-09-27, Last modification date: 2024-01-31) |
| Primary citation | Fregoso, F.E.,Boczkowska, M.,Rebowski, G.,Carman, P.J.,van Eeuwen, T.,Dominguez, R. Mechanism of synergistic activation of Arp2/3 complex by cortactin and WASP-family proteins. Nat Commun, 14:6894-6894, 2023 Cited by PubMed: 37898612DOI: 10.1038/s41467-023-42229-y PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.89 Å) |
Structure validation
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