8TAH
Cryo-EM structure of Cortactin-bound to Arp2/3 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Actin-related protein 3 | polymer | 418 | 47428.0 | 1 | UniProt (P61157) Pfam (PF00022) | Bos taurus (cattle) | Actin-2,Actin-like protein 3 |
| 2 | B (B) | Actin-related protein 2 | polymer | 394 | 44818.7 | 1 | UniProt (A7MB62) Pfam (PF00022) | Bos taurus (cattle) | Actin-like protein 2 |
| 3 | C (C) | Actin-related protein 2/3 complex subunit 1A | polymer | 370 | 41594.2 | 1 | UniProt (Q1JP79) Pfam (PF00400) | Bos taurus (cattle) | |
| 4 | D (D) | Actin-related protein 2/3 complex subunit 2 | polymer | 300 | 34402.0 | 1 | UniProt (Q3MHR7) Pfam (PF04045) | Bos taurus (cattle) | Arp2/3 complex 34 kDa subunit,p34-ARC |
| 5 | E (E) | Actin-related protein 2/3 complex subunit 3 | polymer | 178 | 20572.7 | 1 | UniProt (Q3T035) Pfam (PF04062) | Bos taurus (cattle) | Arp2/3 complex 21 kDa subunit,p21-ARC |
| 6 | F (F) | Actin-related protein 2/3 complex subunit 4 | polymer | 168 | 19697.0 | 1 | UniProt (Q148J6) Pfam (PF05856) | Bos taurus (cattle) | Arp2/3 complex 20 kDa subunit,p20-ARC |
| 7 | G (G) | Actin-related protein 2/3 complex subunit 5 | polymer | 151 | 16309.3 | 1 | UniProt (G3MXC8) | Bos taurus (cattle) | |
| 8 | H (H) | Src substrate cortactin | polymer | 76 | 8684.4 | 1 | UniProt (Q60598) | Mus musculus (house mouse) | |
| 9 | I, K (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 10 | J, L (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 233506.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1063.0 | |
| All* | Total formula weight | 234569.4 |
