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5MEI
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BU of 5mei by Molmil
Crystal structure of Agelastatin A bound to the 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:McClary, B, Zinshteyn, B, Meyer, M, Jouanneau, M, Pellegrino, S, Yusupova, G, Schuller, A, Reyes, J.C.P, Lu, J, Luo, C, Dang, Y, Romo, D, Yusupov, M, Green, R, Liu, J.O.
Deposit date:2016-11-15
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.
Cell Chem Biol, 24, 2017
5FCI
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BU of 5fci by Molmil
Structure of the vacant uL3 W255C mutant 80S yeast ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Mailliot, J, Garreau de Loubresse, N, Yusupova, G, Dinman, J.D, Yusupov, M.
Deposit date:2015-12-15
Release date:2016-05-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency.
J.Mol.Biol., 428, 2016
8BXA
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BU of 8bxa by Molmil
Crystal structure of ribosome binding factor A (RbfA) from S. aureus
Descriptor: Ribosome-binding factor A
Authors:Fatkhullin, B, Bikmullin, A, Gabdulkhakov, A, Khusainov, I, Validov, S, Usachev, K, Yusupov, M.
Deposit date:2022-12-08
Release date:2023-02-22
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Yet Another Similarity between Mitochondrial and Bacterial Ribosomal Small Subunit Biogenesis Obtained by Structural Characterization of RbfA from S. aureus.
Int J Mol Sci, 24, 2023
7OSA
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BU of 7osa by Molmil
Pre-translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligands
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ...
Authors:Djumagulov, M, Jenner, L, Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2021-06-08
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Accuracy mechanism of eukaryotic ribosome translocation.
Nature, 600, 2021
7OSM
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BU of 7osm by Molmil
Intermediate translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligands
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ...
Authors:Djumagulov, M, Jenner, L, Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2021-06-09
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Accuracy mechanism of eukaryotic ribosome translocation.
Nature, 600, 2021
4V4P
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BU of 4v4p by Molmil
Crystal structure of 70S ribosome with thrS operator and tRNAs.
Descriptor: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Jenner, L, Romby, P, Rees, B, Schulze-Briese, C, Springer, M, Ehresmann, C, Ehresmann, B, Moras, D, Yusupova, G, Yusupov, M.
Deposit date:2005-01-19
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Translational operator of mRNA on the ribosome: how repressor proteins exclude ribosome binding.
Science, 308, 2005
5LI0
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BU of 5li0 by Molmil
70S ribosome from Staphylococcus aureus
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Khusainov, I, Vicens, Q, Bochler, A, Grosse, F, Myasnikov, A, Menetret, J.F, Chicher, J, Marzi, S, Romby, P, Yusupova, G, Yusupov, M, Hashem, Y.
Deposit date:2016-07-13
Release date:2016-12-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the 70S ribosome from human pathogen Staphylococcus aureus.
Nucleic Acids Res., 44, 2016
6YEF
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BU of 6yef by Molmil
70S initiation complex with assigned rRNA modifications from Staphylococcus aureus
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ...
Authors:Fatkhullin, B, Golubev, A, Khusainov, I, Yusupova, G, Yusupov, M.
Deposit date:2020-03-24
Release date:2021-01-27
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 angstrom resolution.
Febs Lett., 594, 2020
8CQW
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BU of 8cqw by Molmil
Crystal structure of the Candida albicans 80S ribosome in complex with Hygromycin B
Descriptor: 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ...
Authors:Kolosova, O, Zgadzay, Y, Yusupov, M.
Deposit date:2023-03-07
Release date:2024-09-18
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
To Be Published
8CRE
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BU of 8cre by Molmil
Crystal structure of the Candida albicans 80S ribosome in complex with geneticin G418
Descriptor: 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ...
Authors:Kolosova, O, Zgadzay, Y, Yusupov, M.
Deposit date:2023-03-08
Release date:2024-09-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
To Be Published
8Q87
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BU of 8q87 by Molmil
Structure of the G. gallus 80S rotated ribosome in complex with eEF2 and SERBP1
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Nurullina, L, Jenner, L, Yusupov, M.
Deposit date:2023-08-18
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural insights into inactive ribosome complexes derived from cold-treated chick embryo cells
To Be Published
8Q7Z
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BU of 8q7z by Molmil
Structure of the G. gallus 80S non-rotated ribosome
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Nurullina, L, Jenner, L, Yusupov, M.
Deposit date:2023-08-17
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural insights into inactive ribosome complexes derived from cold-treated chick embryo cells
To Be Published
2VAZ
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BU of 2vaz by Molmil
Model of the S15-mRNA complex fitted into the cryo-EM map of the 70S entrapment complex.
Descriptor: 30S RIBOSOMAL PROTEIN S15, RPSO MRNA OPERATOR
Authors:Marzi, S, Myasnikov, A.G, Serganov, A, Ehresmann, C, Romby, P, Yusupov, M, Klaholz, B.P.
Deposit date:2007-09-05
Release date:2007-10-02
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structured Mrnas Regulate Translation Initiation by Binding to the Platform of the Ribosome.
Cell(Cambridge,Mass.), 130, 2007
7KWG
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BU of 7kwg by Molmil
Staphylococcus aureus 30S ribosomal subunit in presence of spermidine
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Belinite, M, Khusainov, I, Marzi, S, Romby, P, Yusupov, M, Hashem, Y.
Deposit date:2020-11-30
Release date:2021-01-27
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Stabilization of Ribosomal RNA of the Small Subunit by Spermidine in Staphylococcus aureus .
Front Mol Biosci, 8, 2021
5TBW
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BU of 5tbw by Molmil
Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Konst, Z.A, Szklarski, A.R, Pellegrino, S, Michalak, S.E, Meyer, M, Zanette, C, Cencic, R, Nam, S, Horne, D.A, Pelletier, J, Mobley, D.L, Yusupova, G, Yusupov, M, Vanderwal, C.D.
Deposit date:2016-09-13
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.
Nat Chem, 9, 2017
4V8C
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BU of 4v8c by Molmil
Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex with paromomycin).
Descriptor: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2011-12-07
Release date:2014-07-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
4V88
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BU of 4v88 by Molmil
The structure of the eukaryotic ribosome at 3.0 A resolution.
Descriptor: 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ...
Authors:Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M.
Deposit date:2011-10-11
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the eukaryotic ribosome at 3.0 angstrom resolution.
Science, 334, 2011
4V4Z
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BU of 4v4z by Molmil
70S Thermus thermophilous ribosome functional complex with mRNA and E- and P-site tRNAs at 4.5A.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Jenner, L, Yusupova, G, Rees, B, Moras, D, Yusupov, M.
Deposit date:2006-06-27
Release date:2014-07-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (4.51 Å)
Cite:Structural basis for messenger RNA movement on the ribosome.
Nature, 444, 2006
4V4Y
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BU of 4v4y by Molmil
Crystal structure of the 70S Thermus thermophilus ribosome with translocated and rotated Shine-Dalgarno Duplex.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Jenner, L, Yusupova, G, Rees, B, Moras, D, Yusupov, M.
Deposit date:2006-06-27
Release date:2014-07-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Structural basis for messenger RNA movement on the ribosome.
Nature, 444, 2006
4V9B
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BU of 4v9b by Molmil
Crystal Structure of the 70S ribosome with tigecycline.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Jenner, L, Yusupov, M, Yusupova, G.
Deposit date:2012-07-18
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V8D
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BU of 4v8d by Molmil
Structure analysis of ribosomal decoding (cognate tRNA-tyr complex).
Descriptor: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2011-12-07
Release date:2014-07-09
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
4V87
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BU of 4v87 by Molmil
Crystal structure analysis of ribosomal decoding.
Descriptor: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Demeshkina, N, Jenner, L, Yusupov, M, Yusupova, G.
Deposit date:2011-09-20
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
4V6G
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BU of 4v6g by Molmil
Initiation complex of 70S ribosome with two tRNAs and mRNA.
Descriptor: 16S RRNA (E.COLI NUMBERING), 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Jenner, L.B, Yusupova, G, Yusupov, M.
Deposit date:2009-07-10
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural aspects of messenger RNA reading frame maintenance by the ribosome.
Nat.Struct.Mol.Biol., 17, 2010
4V8E
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BU of 4v8e by Molmil
Crystal structure analysis of ribosomal decoding (near-cognate tRNA-tyr complex).
Descriptor: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2011-12-07
Release date:2014-07-09
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
8Q5I
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BU of 8q5i by Molmil
Structure of Candida albicans 80S ribosome in complex with cephaeline
Descriptor: 18S ribosomal RNA, 25S rRNA, 40S ribosomal protein S0, ...
Authors:Kolosova, O, Zgadzay, Y, Stetsenko, A, Atamas, A, Guskov, A, Yusupov, M.
Deposit date:2023-08-09
Release date:2023-09-13
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy
Biopolym Cell, 2023

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