Author results

1H6M
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COVALENT GLYCOSYL-ENZYME INTERMEDIATE OF HEN EGG WHITE LYSOZYME
分子名称:LYSOZYME C, SODIUM ION, 2-deoxy-2-fluoro-alpha-D-glucopyranose, ...
著者Vocadlo, D.J., Davies, G.J., Laine, R., Withers, S.G.
登録日2001-06-19
公開日2001-08-30
最終更新日2019-03-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Catalysis by Hen Egg-White Lysozyme Proceeds Via a Covalent Intermediate
Nature, 412, 2001
1JAK
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STREPTOMYCES PLICATUS BETA-N-ACETYLHEXOSAMINIDASE IN COMPLEX WITH (2R,3R,4S,5R)-2-ACETAMIDO-3,4-DIHYDROXY-5-HYDROXYMETHYL-PIPERIDINIUM CHLORIDE (IFG)
分子名称:Beta-N-acetylhexosaminidase, SULFATE ION, CHLORIDE ION, ...
著者Mark, B.L., Vocadlo, D.J., Zhao, D., Knapp, S., Withers, S.G., James, M.N.
登録日2001-05-30
公開日2001-11-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Biochemical and structural assessment of the 1-N-azasugar GalNAc-isofagomine as a potent family 20 beta-N-acetylhexosaminidase inhibitor.
J.Biol.Chem., 276, 2001
1M01
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WILDTYPE STREPTOMYCES PLICATUS BETA-HEXOSAMINIDASE IN COMPLEX WITH PRODUCT (GLCNAC)
分子名称:Beta-N-acetylhexosaminidase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
著者J Williams, S., Mark, B.L., Vocadlo, D.J., James, M.N.G., Withers, S.G.
登録日2002-06-11
公開日2003-01-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state.
J.Biol.Chem., 277, 2002
1M03
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MUTANT STREPTOMYCES PLICATUS BETA-HEXOSAMINIDASE (D313A) IN COMPLEX WITH PRODUCT (GLCNAC)
分子名称:Beta-N-acetylhexosaminidase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
著者Williams, S.J., Mark, B.L., Vocadlo, D.J., James, M.N.G., Withers, S.G.
登録日2002-06-11
公開日2002-12-11
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state.
J.Biol.Chem., 277, 2002
1M04
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MUTANT STREPTOMYCES PLICATUS BETA-HEXOSAMINIDASE (D313N) IN COMPLEX WITH PRODUCT (GLCNAC)
分子名称:Beta-N-acetylhexosaminidase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
著者Williams, S.J., Mark, B.L., Vocadlo, D.J., James, M.N.G., Withers, S.G.
登録日2002-06-11
公開日2002-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state.
J.Biol.Chem., 277, 2002
1PX8
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CRYSTAL STRUCTURE OF BETA-D-XYLOSIDASE FROM THERMOANAEROBACTERIUM SACCHAROLYTICUM, A FAMILY 39 GLYCOSIDE HYDROLASE
分子名称:Beta-xylosidase, BETA-D-XYLOPYRANOSE
著者Yang, J.K., Yoon, H.J., Ahn, H.J., Il Lee, B., Pedelacq, J.D., Liong, E.C., Berendzen, J., Laivenieks, M., Vieille, C., Zeikus, G.J., Vocadlo, D.J., Withers, S.G., Suh, S.W.
登録日2003-07-03
公開日2003-12-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of beta-D-xylosidase from Thermoanaerobacterium saccharolyticum, a family 39 glycoside hydrolase.
J.Mol.Biol., 335, 2004
1UHV
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CRYSTAL STRUCTURE OF BETA-D-XYLOSIDASE FROM THERMOANAEROBACTERIUM SACCHAROLYTICUM, A FAMILY 39 GLYCOSIDE HYDROLASE
分子名称:Beta-xylosidase, 1,2-DEOXY-2-FLUORO-XYLOPYRANOSE
著者Yang, J.K., Yoon, H.J., Ahn, H.J., Il Lee, B., Pedelacq, J.D., Liong, E.C., Berendzen, J., Laivenieks, M., Vieille, C., Zeikus, G.J., Vocadlo, D.J., Withers, S.G., Suh, S.W.
登録日2003-07-11
公開日2003-12-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of beta-D-xylosidase from Thermoanaerobacterium saccharolyticum, a family 39 glycoside hydrolase.
J.Mol.Biol., 335, 2004
1ZUN
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CRYSTAL STRUCTURE OF A GTP-REGULATED ATP SULFURYLASE HETERODIMER FROM PSEUDOMONAS SYRINGAE
分子名称:Sulfate adenylyltransferase subunit 2, sulfate adenylate transferase, subunit 1/adenylylsulfate kinase, ...
著者Mougous, J.D., Lee, D.H., Hubbard, S.C., Schelle, M.W., Vocadlo, D.J., Berger, J.M., Bertozzi, C.R.
登録日2005-05-31
公開日2006-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis for g protein control of the prokaryotic ATP sulfurylase.
Mol.Cell, 21, 2006
2CHN
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BACTEROIDES THETAIOTAOMICRON HEXOSAMINIDASE WITH O-GLCNACASE ACTIVITY- NAG-THIAZOLINE COMPLEX
分子名称:GLUCOSAMINIDASE, CALCIUM ION, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, ...
著者Dennis, R.J., Taylor, E.J., Macauley, M.S., Stubbs, K.A., Turkenburg, J.P., Hart, S.J., Black, G.N., Vocadlo, D.J., Davies, G.J.
登録日2006-03-15
公開日2006-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and Mechanism of a Bacterial B-Glucosaminidase Having O-Glcnacase Activity
Nat.Struct.Mol.Biol., 13, 2006
2CHO
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BACTEROIDES THETAIOTAOMICRON HEXOSAMINIDASE WITH O-GLCNACASE ACTIVITY
分子名称:GLUCOSAMINIDASE, CALCIUM ION, ACETATE ION, ...
著者Dennis, R.J., Taylor, E.J., Macauley, M.S., Stubbs, K.A., Turkenburg, J.P., Hart, S.J., Black, G.N., Vocadlo, D.J., Davies, G.J.
登録日2006-03-16
公開日2006-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure and Mechanism of a Bacterial B-Glucosaminidase Having O-Glcnacase Activity
Nat.Struct.Mol.Biol., 13, 2006
2VC9
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FAMILY 89 GLYCOSIDE HYDROLASE FROM CLOSTRIDIUM PERFRINGENS IN COMPLEX WITH 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN
分子名称:ALPHA-N-ACETYLGLUCOSAMINIDASE, 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN, GLYCEROL, ...
著者Ficko-Blean, E., Stubbs, K.A., Berg, O., Vocadlo, D.J., Boraston, A.B.
登録日2007-09-19
公開日2008-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VCA
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FAMILY 89 GLYCOSIDE HYDROLASE FROM CLOSTRIDIUM PERFRINGENS IN COMPLEX WITH BETA-N-ACETYL-D-GLUCOSAMINE
分子名称:ALPHA-N-ACETYLGLUCOSAMINIDASE, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ...
著者Ficko-Blean, E., Stubbs, K.A., Berg, O., Vocadlo, D.J., Boraston, A.B.
登録日2007-09-19
公開日2008-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VCB
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FAMILY 89 GLYCOSIDE HYDROLASE FROM CLOSTRIDIUM PERFRINGENS IN COMPLEX WITH PUGNAC
分子名称:ALPHA-N-ACETYLGLUCOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, CALCIUM ION
著者Ficko-Blean, E., Stubbs, K.A., Berg, O., Vocadlo, D.J., Boraston, A.B.
登録日2007-09-19
公開日2008-03-18
最終更新日2011-08-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VCC
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FAMILY 89 GLYCOSIDE HYDROLASE FROM CLOSTRIDIUM PERFRINGENS
分子名称:ALPHA-N-ACETYLGLUCOSAMINIDASE, GLYCEROL, SULFATE ION, ...
著者Ficko-Blean, E., Stubbs, K.A., Berg, O., Vocadlo, D.J., Boraston, A.B.
登録日2007-09-19
公開日2008-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VVS
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BTGH84 STRUCTURE IN COMPLEX WITH PUGNAC
分子名称:O-GLCNACASE BT_4395, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE
著者Macauley, M.S., Bubb, A., Martinez-Fleites, C., Davies, G.J., Vocadlo, D.J.
登録日2008-06-11
公開日2008-09-30
最終更新日2011-08-24
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Elevation of Global O-Glcnac Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-Glcnacase Does not Induce Insulin Resistance
J.Biol.Chem., 283, 2008
2W91
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STRUCTURE OF A STREPTOCOCCUS PNEUMONIAE FAMILY 85 GLYCOSIDE HYDROLASE, ENDO-D.
分子名称:ENDO-BETA-N-ACETYLGLUCOSAMINIDASE D, PENTAETHYLENE GLYCOL
著者Abbott, D.W., Macauley, M.S., Vocadlo, D.J., Boraston, A.B.
登録日2009-01-21
公開日2009-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Streptococcus Pneumoniae Endohexosaminidase D, Structural and Mechanistic Insight Into Substrate-Assisted Catalysis in Family 85 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
2W92
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STRUCTURE OF A STREPTOCOCCUS PNEUMONIAE FAMILY 85 GLYCOSIDE HYDROLASE, ENDO-D, IN COMPLEX WITH NAG-THIAZOLINE.
分子名称:ENDO-BETA-N-ACETYLGLUCOSAMINIDASE D, PENTAETHYLENE GLYCOL, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL
著者Abbott, D.W., Macauley, M.S., Vocadlo, D.J., Boraston, A.B.
登録日2009-01-21
公開日2009-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Streptococcus Pneumoniae Endohexosaminidase D, Structural and Mechanistic Insight Into Substrate-Assisted Catalysis in Family 85 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
2WAR
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HEN EGG WHITE LYSOZYME E35Q CHITOPENTAOSE COMPLEX
分子名称:LYSOZYME C, N-ACETYL-D-GLUCOSAMINE
著者Davies, G.J., Withers, S.G., Vocadlo, D.J.
登録日2009-02-13
公開日2010-02-09
最終更新日2019-01-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Chitopentaose Complex of a Mutant Hen Egg-White Lysozyme Displays No Distortion of the -1 Sugar Away from a 4C1 Chair Conformation
Aust.J.Chem., 62, 2009
2WMF
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CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE TIGR4 (SP4GH98) IN ITS NATIVE FORM.
分子名称:FUCOLECTIN-RELATED PROTEIN
著者Higgins, M.A., Whitworth, G.E., El Warry, N., Randriantsoa, M., Samain, E., Burke, R.D., Vocadlo, D.J., Boraston, A.B.
登録日2009-06-30
公開日2009-07-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
2WMG
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CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE TIGR4 (SP4GH98) IN COMPLEX WITH THE LEWISY PENTASACCHARIDE BLOOD GROUP ANTIGEN.
分子名称:FUCOLECTIN-RELATED PROTEIN, ALPHA-L-FUCOSE, BETA-D-GALACTOSE, ...
著者Higgins, M.A., Whitworth, G.E., El Warry, N., Randriantsoa, M., Samain, E., Burke, R.D., Vocadlo, D.J., Boraston, A.B.
登録日2009-06-30
公開日2009-07-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
2WMH
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CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE TIGR4 IN COMPLEX WITH THE H- DISACCHARIDE BLOOD GROUP ANTIGEN.
分子名称:FUCOLECTIN-RELATED PROTEIN, BETA-D-GALACTOSE, ALPHA-L-FUCOSE
著者Higgins, M.A., Whitworth, G.E., El Warry, N., Randriantsoa, M., Samain, E., Burke, R.D., Vocadlo, D.J., Boraston, A.B.
登録日2009-06-30
公開日2009-07-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
2WMI
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CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE SP3-BS71 IN COMPLEX WITH THE A-TRISACCHARIDE BLOOD GROUP ANTIGEN.
分子名称:FUCOLECTIN-RELATED PROTEIN, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, BETA-D-GALACTOSE, ...
著者Higgins, M.A., Whitworth, G.E., El Warry, N., Randriantsoa, M., Samain, E., Burke, R.D., Vocadlo, D.J., Boraston, A.B.
登録日2009-06-30
公開日2009-07-14
最終更新日2012-11-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
2WMJ
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CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE SP3-BS71 (SP3GH98) IN COMPLEX WITH THE B-TRISACCHARIDE BLOOD GROUP ANTIGEN.
分子名称:FUCOLECTIN-RELATED PROTEIN, ALPHA D-GALACTOSE, BETA-D-GALACTOSE, ...
著者Higgins, M.A., Whitworth, G.E., El Warry, N., Randriantsoa, M., Samain, E., Burke, R.D., Vocadlo, D.J., Boraston, A.B.
登録日2009-06-30
公開日2009-07-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
2WMK
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CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE SP3-BS71 (SP3GH98) IN COMPLEX WITH THE A-LEWISY PENTASACCHARIDE BLOOD GROUP ANTIGEN.
分子名称:FUCOLECTIN-RELATED PROTEIN, ALPHA-L-FUCOSE, BETA-D-GALACTOSE, ...
著者Higgins, M.A., Whitworth, G.E., El Warry, N., Randriantsoa, M., Samain, E., Burke, R.D., Vocadlo, D.J., Boraston, A.B.
登録日2009-06-30
公開日2009-07-14
最終更新日2012-11-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
2YA0
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CATALYTIC MODULE OF THE MULTI-MODULAR GLYCOGEN-DEGRADING PNEUMOCOCCAL VIRULENCE FACTOR SPUA
分子名称:PUTATIVE ALKALINE AMYLOPULLULANASE, CALCIUM ION, GLYCEROL, ...
著者Lammerts van Bueren, A., Ficko-Blean, E., Pluvinage, B., Hehemann, J.H., Higgins, M.A., Deng, L., Ogunniyi, A.D., Stroeher, U.H., Warry, N.E., Burke, R.D., Czjzek, M., Paton, J.C., Vocadlo, D.J., Boraston, A.B.
登録日2011-02-17
公開日2011-04-20
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Conformation and Function of a Multimodular Glycogen-Degrading Pneumococcal Virulence Factor.
Structure, 19, 2011