PDB: 339 resultsInfo pagesStatus searchChemie searchBIRD

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3S8E	Phosphorylation regulates assembly of the caspase-6 substrate-binding groove Descriptor: Caspase-6 Authors: Velazquez-Delgado, E.M, Hardy, J.A. Deposit date: 2011-05-27 Release date: 2012-04-11 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.88 Å) Cite: Phosphorylation regulates assembly of the caspase-6 substrate-binding groove. Structure, 20, 2012
4AFR	THE STRUCTURE OF METACASPASE 2 (C213A MUTANT) FROM T. BRUCEI Descriptor: METACASPASE Authors: McLuskey, K, Rudolf, J, Isaacs, N.W, Coombs, G.H, Moss, C.X, Mottram, J.C. Deposit date: 2012-01-23 Release date: 2012-05-02 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure of a Trypanosoma Brucei Metacaspase. Proc.Natl.Acad.Sci.USA, 109, 2012
4AFP	The structure of metacaspase 2 from T. brucei determined in the presence of Samarium Descriptor: METACASPASE MCA2, SAMARIUM (III) ION Authors: McLuskey, K, Rudolf, J, Isaacs, N.W, Coombs, G.H, Moss, C.X, Mottram, J.C. Deposit date: 2012-01-23 Release date: 2012-05-02 Last modified: 2017-07-05 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structure of a Trypanosoma Brucei Metacaspase. Proc.Natl.Acad.Sci.USA, 109, 2012
4AF8	The structural basis for metacaspase substrate specificity and activation Descriptor: CHLORIDE ION, METACASPASE MCA2, SODIUM ION Authors: McLuskey, K, Rudolf, J, Isaacs, N.W, Coombs, G.H, Moss, C.X, Mottram, J.C. Deposit date: 2012-01-18 Release date: 2012-05-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal Structure of a Trypanosoma Brucei Metacaspase. Proc.Natl.Acad.Sci.USA, 109, 2012
4AFV	THE STRUCTURE OF METACASPASE 2 FROM T. BRUCEI DETERMINED IN THE PRESENCE OF CALCIUM CHLORIDE Descriptor: METACASPASE MCA2 Authors: McLuskey, K, Rudolf, J, Isaacs, N.W, Coombs, G.H, Moss, C.X, Mottram, J.C. Deposit date: 2012-01-23 Release date: 2012-05-02 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal Structure of a Trypanosoma Brucei Metacaspase. Proc.Natl.Acad.Sci.USA, 109, 2012
4EHL	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.799 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4EHD	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.581 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4EHN	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4EHF	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.655 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4EHK	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.668 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4EHA	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.696 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4EHH	Allosteric Modulation of Caspase-3 through Mutagenesis Descriptor: ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 Authors: Walters, J, Schipper, J.L, Swartz, P.D, Mattos, C, Clark, A.C. Deposit date: 2012-04-02 Release date: 2012-06-06 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Allosteric modulation of caspase 3 through mutagenesis. Biosci.Rep., 32, 2012
4EJF	Allosteric peptides that bind to a caspase zymogen and mediate caspase tetramerization Descriptor: Caspase-6, PHOSPHATE ION, phage-derived peptide 419 Authors: Murray, J.M. Deposit date: 2012-04-06 Release date: 2012-06-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.6465 Å) Cite: Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization. Nat.Chem.Biol., 8, 2012
4F6O	Crystal structure of the yeast metacaspase Yca1 Descriptor: 1,1-diphenylethanol, Metacaspase-1 Authors: Wong, A.H, Yan, C.Y, Shi, Y.G. Deposit date: 2012-05-15 Release date: 2012-07-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.681 Å) Cite: Crystal structure of the yeast metacaspase Yca1. J.Biol.Chem., 287, 2012
4FDL	Crystal structure of Caspase-7 Descriptor: Caspase-7 Authors: Kabaleeswaran, V. Deposit date: 2012-05-28 Release date: 2012-08-01 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.801 Å) Cite: A class of allosteric caspase inhibitors identified by high-throughput screening. Mol.Cell, 47, 2012
4FEA	Crystal structure of CASPASE-7 in Complex with allosteric inhibitor Descriptor: Caspase-7, chloro{methyl hydrogenato(3-)-kappa~2~N,S [pyridin-2-yl(pyridin-2(1H)-ylidene-kappaN)methyl]carbonodithiohydrazonate}copper Authors: Kabaleeswaran, V. Deposit date: 2012-05-29 Release date: 2012-08-01 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.79 Å) Cite: A class of allosteric caspase inhibitors identified by high-throughput screening. Mol.Cell, 47, 2012
4FXO	Zinc-mediated allosteric inhibiton of caspase-6 Descriptor: Caspase-6, ZINC ION Authors: Velazquez-Delgado, E.M, Hardy, J.A. Deposit date: 2012-07-03 Release date: 2012-08-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Zinc-mediated Allosteric Inhibition of Caspase-6. J.Biol.Chem., 287, 2012
4DCP	Crystal Structure of caspase 3, L168F mutant Descriptor: Caspase Inhibitor AC-DEVD-CHO, Caspase-3 subunit p12, Caspase-3 subunit p17 Authors: Chung, S.J, Kang, H.J, Kim, S.J. Deposit date: 2012-01-18 Release date: 2012-12-12 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7 Biosci.Rep., 32, 2012
4DCJ	Crystal structure of caspase 3, L168D mutant Descriptor: Caspase Inhibitor AC-DEVD-CHO, Caspase-3 subunit p12, Caspase-3 subunit p17 Authors: Chung, S.J, Kang, H.J, Kim, S.J. Deposit date: 2012-01-17 Release date: 2012-12-12 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7 Biosci.Rep., 32, 2012
4DCO	Crystal Structure of caspase 3, L168Y mutant Descriptor: Caspase Inhibitor AC-DEVD-CHO, Caspase-3 subunit p12, Caspase-3 subunit p17 Authors: Chung, S.J, Kang, H.J, Kim, S.J. Deposit date: 2012-01-18 Release date: 2012-12-12 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7 Biosci.Rep., 32, 2012
3V3K	Human caspase 9 in complex with bacterial effector protein Descriptor: Caspase-9, Putative uncharacterized protein ECs1815 Authors: Moertl, M, Maskos, K, Steuber, H. Deposit date: 2011-12-13 Release date: 2013-03-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.494 Å) Cite: Human caspase 9 in complex with bacterial effector protein Plos One, 2013
4HVA	Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6 Descriptor: Caspase-6, N-[(2R)-1-(3-cyanophenyl)-3-hydroxypropan-2-yl]-5-(3,4-dimethoxyphenyl)furan-3-carboxamide, VEID Inhibitor Authors: Murray, J.M, Steffek, M. Deposit date: 2012-11-05 Release date: 2013-03-20 Method: X-RAY DIFFRACTION (2.074 Å) Cite: Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6. Plos One, 7, 2012
4F6P	Crystal structure of the yeast metacaspase Yca1 C276A mutant Descriptor: 1,1-diphenylethanol, Metacaspase-1 Authors: Wong, A.H, Yan, C.Y, Shi, Y.G. Deposit date: 2012-05-15 Release date: 2013-03-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.619 Å) Cite: Crystal structure of the metacaspase Yca1 To be Published
4JQZ	Human procaspase-3, crystal form 2 Descriptor: Procaspase-3 Authors: Thomsen, N.D, Wells, J.A. Deposit date: 2013-03-20 Release date: 2013-05-08 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.889 Å) Cite: Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation. Proc.Natl.Acad.Sci.USA, 110, 2013
4JR0	Human procaspase-3 bound to Ac-DEVD-CMK Descriptor: Ac-DEVD-CMK, CHLORIDE ION, Procaspase-3 Authors: Thomsen, N.D, Wells, J.A. Deposit date: 2013-03-20 Release date: 2013-05-08 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.796 Å) Cite: Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation. Proc.Natl.Acad.Sci.USA, 110, 2013

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