4DCJ

Crystal structure of caspase 3, L168D mutant

Summary for 4DCJ

• Entry DOI: 10.2210/pdb4dcj/pdb
• Related: 4DCO 4DCP
• Related PRD ID: PRD_000422
• Descriptor: Caspase-3 subunit p17, Caspase-3 subunit p12, Caspase Inhibitor AC-DEVD-CHO, ... (4 entities in total)
• Functional Keywords: alpha/beta hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P42574 P42574
• Total number of polymer chains: 6
• Total formula weight: 59739.61

Authors

Chung, S.J.,Kang, H.J.,Kim, S.J. (deposition date: 2012-01-17, release date: 2012-12-12)

• Primary citation: Kang, H.J.,Lee, Y.M.,Jeong, M.S.,Kim, M.,Bae, K.H.,Kim, S.J.,Chung, S.J.; Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7; Biosci.Rep., 32:305-313, 2012; PubMed: 22304005; DOI: 10.1042/BSR20120009

Experimental method

X-RAY DIFFRACTION (1.7 Å)