4FXO

Zinc-mediated allosteric inhibiton of caspase-6

Summary for 4FXO

Entry DOI	10.2210/pdb4fxo/pdb
Related	2WDP 3K7E 3NKF 3OD5 3S8E
Descriptor	Caspase-6, ZINC ION (3 entities in total)
Functional Keywords	heterotetramer, hydrolase, cytosol, apoptosis
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P55212
Total number of polymer chains	4
Total formula weight	137013.18
Authors	Velazquez-Delgado, E.M.,Hardy, J.A. (deposition date: 2012-07-03, release date: 2012-08-22, Last modification date: 2023-09-13)
Primary citation	Velazquez-Delgado, E.M.,Hardy, J.A. Zinc-mediated Allosteric Inhibition of Caspase-6. J.Biol.Chem., 287:36000-36011, 2012 Cited by PubMed: 22891250 DOI: 10.1074/jbc.M112.397752 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation