4JUO

A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32

Summary for 4JUO

Entry DOI	10.2210/pdb4juo/pdb
Related	2NOV 3FOE 3FOF 3K9F 3KSA 3KSB 3LTN 3RAD 3RAE 3RAF 4I3H
Descriptor	DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, E-site DNA, ... (8 entities in total)
Functional Keywords	full-length pare, parc55, open n-gate, topoisomerase iia, atp binding, isomerase-dna complex, isomerase/dna
Biological source	Streptococcus pneumoniae More
Cellular location	Cell membrane ; Peripheral membrane protein : P72525
Total number of polymer chains	6
Total formula weight	147276.03
Authors	Laponogov, I.,Veselkov, D.A.,Pan, X.-S.,Crevel, I.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2013-03-25, release date: 2013-08-28, Last modification date: 2023-09-20)
Primary citation	Laponogov, I.,Veselkov, D.A.,Crevel, I.M.,Pan, X.S.,Fisher, L.M.,Sanderson, M.R. Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport. Nucleic Acids Res., 41:9911-9923, 2013 Cited by PubMed: 23965305 DOI: 10.1093/nar/gkt749 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (6.53 Å)

Structure validation