3FOF
Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases
Summary for 3FOF
Entry DOI | 10.2210/pdb3fof/pdb |
Related | 2NOV 3FOE |
Descriptor | DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, DNA (5'-D(P*AP*CP*CP*AP*AP*GP*GP*TP*CP*AP*TP*GP*AP*AP*T)-3'), ... (7 entities in total) |
Functional Keywords | quinolone, topoisomerase, dna, protein-dna cleavage complex, streptococcus pneumoniae, moxifloxacin, cell membrane, dna-binding, isomerase, membrane, atp-binding, nucleotide-binding, isomerase-dna complex, isomerase/dna |
Biological source | Streptococcus pneumoniae More |
Cellular location | Cell membrane; Peripheral membrane protein (By similarity): P72525 |
Total number of polymer chains | 8 |
Total formula weight | 195370.72 |
Authors | Laponogov, I.,Sohi, M.K.,Veselkov, D.A.,Pan, X.-S.,Sawhney, R.,Thompson, A.W.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2008-12-30, release date: 2009-02-24, Last modification date: 2023-11-01) |
Primary citation | Laponogov, I.,Sohi, M.K.,Veselkov, D.A.,Pan, X.-S.,Sawhney, R.,Thompson, A.W.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases Nat.Struct.Mol.Biol., 16:667-669, 2009 Cited by PubMed: 19448616DOI: 10.1038/nsmb.1604 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4 Å) |
Structure validation
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