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3K9F

Detailed structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases

Summary for 3K9F
Entry DOI10.2210/pdb3k9f/pdb
Related2NOV 3FOE 3FOF
DescriptorDNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, DNA (5'-D(*AP*CP*CP*AP*AP*GP*GP*T*CP*AP*TP*GP*AP*AP*T)-3'), ... (9 entities in total)
Functional Keywordsquinolone, topoisomerase, dna, protein-dna cleavage complex, streptococcus pneumoniae, levofloxacin, cell membrane, dna-binding, isomerase, membrane, atp-binding, nucleotide-binding, isomerase-dna complex, isomerase/dna
Biological sourceStreptococcus pneumoniae
More
Cellular locationCell membrane; Peripheral membrane protein (By similarity): P72525
Total number of polymer chains8
Total formula weight195339.21
Authors
Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2009-10-15, release date: 2009-10-27, Last modification date: 2023-11-01)
Primary citationLaponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R.
Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases
Plos One, 5:e11338-e11338, 2010
Cited by
PubMed: 20596531
DOI: 10.1371/journal.pone.0011338
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

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