3RAF

Quinazolinedione-DNA cleavage complex of type IV topoisomerase from S. pneumoniae

Summary for 3RAF

• Entry DOI: 10.2210/pdb3raf/pdb
• Related: 2NOV 3FOE 3FOF 3K9F 3KSA 3KSB 3LTN 3RAD 3RAE
• Descriptor: DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, 5'-D(*CP*AP*TP*GP*AP*AP*T)-3', ... (9 entities in total)
• Functional Keywords: protein-dna cleavage complex, topoisomerase iia, quinazolinedione pd 0305970, isomerase-dna-antibiotic complex, isomerase/dna/antibiotic
• Biological source: Streptococcus pneumoniae; More
• Cellular location: Cell membrane; Peripheral membrane protein (By similarity): P72525
• Total number of polymer chains: 8
• Total formula weight: 185503.59

Authors

Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2011-03-28, release date: 2012-03-28)

• Primary citation: Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R.; Inhibitor-stabilised cleavage complexes of topoisomerase IIa: structural analysis of drug-dependent inter- and intramolecular interactions; To be Published,

Experimental method

X-RAY DIFFRACTION (3.24 Å)