2JYW
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SOLUTION STRUCTURE OF C-TERMINAL DOMAIN OF APOBEC3G
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G (E.C.3.5.4.-)
Authors:Chen, K., Harjes, E., Gross, P.J., Fahmy, A., Lu, Y., Shindo, K., Harris, R.S., Matsuo, H.
Deposit date:2007-12-20
Release date:2008-02-26
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G.
Nature, 452, 2008
2KBO
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STRUCTURE, INTERACTION, AND REAL-TIME MONITORING OF THE ENZYMATIC REACTION OF WILD TYPE APOBEC3G
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G (E.C.3.5.4.-)
Authors:Furukawa, A., Nagata, T., Matsugami, A., Habu, Y., Sugiyama, R., Hayashi, F., Kobayashi, N., Yokoyama, S., Takaku, H., Katahira, M.
Deposit date:2008-12-04
Release date:2009-02-03
Modification date:2009-04-07
Method:SOLUTION NMR
Cite:Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G
Embo J., 28, 2009
2KEM
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EXTENDED STRUCTURE OF CITIDINE DEAMINASE DOMAIN OF APOBEC3G
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G (E.C.3.5.4.-)
Authors:Harjes, E., Gross, P.J., Chen, K., Lu, Y., Shindo, K., Nowarski, R., Gross, J.D., Kotler, M., Harris, R.S., Matsuo, H.
Deposit date:2009-01-30
Release date:2009-06-02
Modification date:2009-07-07
Method:SOLUTION NMR
Cite:An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model
J.Mol.Biol., 389, 2009
2M65
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NMR STRUCTURE OF HUMAN RESTRICTION FACTOR APOBEC3A
Descriptor:Probable DNA dC->dU-editing enzyme APOBEC-3A (E.C.3.5.4.-)
Authors:Byeon, I.L., Byeon, C., Ahn, J., Gronenborn, A.M.
Deposit date:2013-03-21
Release date:2013-05-22
Modification date:2013-06-19
Method:SOLUTION NMR
Cite:NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity.
Nat Commun, 4, 2013
2NYT
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THE APOBEC2 CRYSTAL STRUCTURE AND FUNCTIONAL IMPLICATIONS FOR AID
Descriptor:APOBEC2
Authors:Prochnow, C., Bransteitter, R., Klein, M., Goodman, M., Chen, X.
Deposit date:2006-11-21
Release date:2007-01-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The APOBEC-2 crystal structure and functional implications for the deaminase AID.
Nature, 445, 2007
3E1U
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THE CRYSTAL STRUCTURE OF THE ANTI-VIRAL APOBEC3G CATALYTIC DOMAIN
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G (E.C.3.5.4.-)
Authors:Holden, L., Prochnow, C., Chang, Y.P., Bransteitter, R., Chelico, L., Sen, U., Stevens, R.C., Goodman, R.F., Chen, X.S.
Deposit date:2008-08-04
Release date:2008-10-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Nature, 456, 2008
3IQS
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CRYSTAL STRUCTURE OF THE ANTI-VIRAL APOBEC3G CATALYTIC DOMAIN
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G (E.C.3.5.4.-)
Authors:Holden, L.G., Prochnow, C., Chang, Y.P., Bransteitter, R., Chelico, L., Sen, U., Stevens, R.C., Goodman, R.F., Chen, X.S.
Deposit date:2009-08-20
Release date:2009-11-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Nature, 456, 2008
3IR2
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CRYSTAL STRUCTURE OF THE APOBEC3G CATALYTIC DOMAIN
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G (E.C.3.5.4.-)
Authors:Shandilya, S.M.D., Schiffer, C.A.
Deposit date:2009-08-21
Release date:2010-01-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces.
Structure, 18, 2010
3V4J
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FIRST-IN-CLASS SMALL MOLECULE INHIBITORS OF THE SINGLE-STRAND DNA CYTOSINE DEAMINASE APOBEC3G
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G (E.C.3.5.4.-)
Authors:Shandilya, S.M.D., Ali, A., Schiffer, C.A.
Deposit date:2011-12-15
Release date:2012-02-01
Modification date:2012-03-28
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G.
Acs Chem.Biol., 7, 2012
3V4K
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FIRST-IN-CLASS SMALL MOLECULE INHIBITORS OF THE SINGLE-STRAND DNA CYTOSINE DEAMINASE APOBEC3G
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G (E.C.3.5.4.-)
Authors:Shandilya, S.M.D., Ali, A., Schiffer, C.A.
Deposit date:2011-12-15
Release date:2012-01-25
Modification date:2012-03-28
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G.
Acs Chem.Biol., 7, 2012
4ROV
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THE CRYSTAL STRUCTURE OF NOVEL APOBEC3G CD2 HEAD-TO-TAIL DIMER SUGGESTS THE BINDING MODE OF FULL-LENGTH APOBEC3G TO HIV-1 SSDNA
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G (E.C.3.5.4.-)
Authors:Lu, X., Zhang, T., Xu, Z., Liu, S., Zhao, B., Lan, W., Wang, C., Ding, J., Cao, C.
Deposit date:2014-10-29
Release date:2014-12-31
Modification date:2016-02-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
J.Biol.Chem., 290, 2015
4ROW
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THE CRYSTAL STRUCTURE OF NOVEL APOBEC3G CD2 HEAD-TO-TAIL DIMER SUGGESTS THE BINDING MODE OF FULL-LENGTH APOBEC3G TO HIV-1 SSDNA
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G (E.C.3.5.4.-)
Authors:Lu, X., Zhang, T., Xu, Z., Liu, S., Zhao, B., Lan, W., Wang, C., Ding, J., Cao, C.
Deposit date:2014-10-29
Release date:2014-12-31
Modification date:2016-02-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
J.Biol.Chem., 290, 2015
4XXO
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CRYSTAL STRUCTURE OF HUMAN APOBEC3A
Descriptor:APOBEC3A (E.C.3.5.4,-)
Authors:Bohn, M.F., Shandilya, S.M.D., Schiffer, C.A.
Deposit date:2015-01-30
Release date:2015-04-29
Modification date:2015-05-20
Method:X-RAY DIFFRACTION (2.843 Å)
Cite:The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.
Structure, 23, 2015
5CQD
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CRYSTAL STRUCTURE OF THE CANCER GENOMIC DNA MUTATOR APOBEC3B
Descriptor:DNA dC-dU-editing enzyme APOBEC-3B (E.C.3.5.4.-)
Authors:Shi, K., Kurahashi, K., Aihara, H.
Deposit date:2015-07-21
Release date:2015-10-07
Modification date:2015-12-02
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
J.Biol.Chem., 290, 2015
5CQH
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CRYSTAL STRUCTURE OF THE CANCER GENOMIC DNA MUTATOR APOBEC3B
Descriptor:DNA dC-dU-editing enzyme APOBEC-3B (E.C.3.5.4.-)
Authors:Shi, K., Kurahashi, K., Aihara, H.
Deposit date:2015-07-21
Release date:2015-10-07
Modification date:2015-12-02
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
J.Biol.Chem., 290, 2015
5CQI
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CRYSTAL STRUCTURE OF THE CANCER GENOMIC DNA MUTATOR APOBEC3B
Descriptor:DNA dC-dU-editing enzyme APOBEC-3B (E.C.3.5.4.-)
Authors:Shi, K., Kurahashi, K., Aihara, H.
Deposit date:2015-07-21
Release date:2015-10-07
Modification date:2015-12-02
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
J.Biol.Chem., 290, 2015
5CQK
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CRYSTAL STRUCTURE OF THE CANCER GENOMIC DNA MUTATOR APOBEC3B
Descriptor:DNA dC-dU-editing enzyme APOBEC-3B (E.C.3.5.4.-)
Authors:Shi, K., Kurahashi, K., Aihara, H.
Deposit date:2015-07-21
Release date:2015-10-07
Modification date:2015-12-02
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
J.Biol.Chem., 290, 2015
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